The Impact of Social Networks on Enhancing Safety and Efficacy Outcomes in Low-Dose Rituximab Treatment for Central Nervous System Demyelinating Diseases | ||
| Interdisciplinary Journal of Virtual Learning in Medical Sciences | ||
| مقاله 4، دوره 14، شماره 3 - شماره پیاپی 54، پاییز 2023، صفحه 206-215 اصل مقاله (596.52 K) | ||
| نوع مقاله: Original Article | ||
| شناسه دیجیتال (DOI): 10.30476/ijvlms.2023.99354.1240 | ||
| نویسندگان | ||
| Mohsen Nabiuni1؛ Mahisa Mokhtari2؛ Jaber Hatam3؛ Maziar Emamikhah4؛ Meysam Abolmaali5؛ Elaheh Amini4؛ Parisa Saiyarsarai6، 7؛ Mehdi Moghaddasi* 4؛ Maryam Milanifard8؛ Sana Nabiuni9؛ Hosna Nabiuni10 | ||
| 1Assistant Professor and Chief of Neurosurgery Department, School of Medicine, Iran University of Medical Sciences, Tehran, Iran | ||
| 2Assistant Professor of Neurology Department, School of Medicine, Iran University of Medical Sciences, Tehran, Iran | ||
| 3Assistant Professor of Neurosurgery Department, School of Medicine, Iran University of Medical Sciences, Tehran, Iran | ||
| 4Department of Neurology, Rasool-e Akram Hospital, School of Medicine, Iran University of Medical Sciences, Tehran, Iran | ||
| 5Shefa Neuroscience Research Center, Khatam Al Anbia Hospital, Tehran, Iran | ||
| 6Department of Pharmacoeconomics and Pharmaceutical Administration, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran | ||
| 7The Institute of Pharmaceutical Sciences, Tehran University of Medical Sciences, Tehran, Iran | ||
| 8Department of Anatomical Sciences, School of Medicine, Iran university of Medical Sciences, Tehran, Iran | ||
| 9Pharmacist, University College London, England, London | ||
| 10Medical Student, Iran university of Medical Sciences, Tehran, Iran | ||
| چکیده | ||
| Background: In the realm of healthcare, the symbiotic relationship between social networks and medical advancements has attracted significant attention. This study aimed to explore the effectiveness and safety of this approach, with a particular focus on the role of social networks in disseminating information and shaping patient experiences. Methods: In a prospective single-arm interventional study, we examined the effects of integrating social networks – Skype and WhatsApp – to enhance the safety and efficacy outcomes of low-dose Rituximab treatment for CNS Demyelinating Diseases. A total of 99 patients eligible for treatment were recruited, and ethical consent was secured. The intervention involved informative Skype groups, led by medical experts, providing education and follow-up, and WhatsApp groups for peer support and question-answer sessions. Clinical data and interaction metrics were collected to evaluate treatment outcomes and engagement levels. Results: A total of 99 patients received rituximab, with 42 diagnosed with RRMS, 43 with SPMS, and 14 with Neuromyelitis Optica Spectrum Disorder (NMOSD). The treatment period ranged from 12 to 40 months. Among the Relapsing-remitting Multiple Sclerosis (RRMS) patients, 8 (19%) experienced new attacks, while 10 (23%) of the Secondary-progressive Multiple Sclerosis (SPMS) patients and 1 (7%) of the NMOSD patients had new attacks. In cases of RRMS and NMOSD, there was a decrease in Expanded Disability Status Scale (EDSS) scores. Additionally, SPMS and NMOSD patients showed a decrement in serum IgG levels. Two cases of drug adverse events were reported. Mean EDSS variability had a decrease in RRMS (-0.32, P=0.06) and NMOSD (-0.57, P=0.004) and had a slight increase among patients with SPMS (+0.19, P=0.23). Conclusion: Recognizing the influence of social networks can enhance patient care and create customized support systems. By combining findings from clinical evaluations with insights gained from social media interactions, we could provide a multifaceted perspective on safety and effectiveness. | ||
| کلیدواژهها | ||
| Distance؛ Social Networking؛ Teaching؛ Multiple Sclerosis | ||
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