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Nabiuni, Mohsen, Mokhtari, Mahisa, Hatam, Jaber, Emamikhah, Maziar, Abolmaali, Meysam, Amini, Elaheh, Saiyarsarai, Parisa, Moghaddasi, Mehdi, Milanifard, Maryam, Nabiuni, Sana, Nabiuni, Hosna. (1402). The Impact of Social Networks on Enhancing Safety and Efficacy Outcomes in Low-Dose Rituximab Treatment for Central Nervous System Demyelinating Diseases. سامانه مدیریت نشریات علمی, 14(3), 206-215. doi: 10.30476/ijvlms.2023.99354.1240
Mohsen Nabiuni; Mahisa Mokhtari; Jaber Hatam; Maziar Emamikhah; Meysam Abolmaali; Elaheh Amini; Parisa Saiyarsarai; Mehdi Moghaddasi; Maryam Milanifard; Sana Nabiuni; Hosna Nabiuni. "The Impact of Social Networks on Enhancing Safety and Efficacy Outcomes in Low-Dose Rituximab Treatment for Central Nervous System Demyelinating Diseases". سامانه مدیریت نشریات علمی, 14, 3, 1402, 206-215. doi: 10.30476/ijvlms.2023.99354.1240
Nabiuni, Mohsen, Mokhtari, Mahisa, Hatam, Jaber, Emamikhah, Maziar, Abolmaali, Meysam, Amini, Elaheh, Saiyarsarai, Parisa, Moghaddasi, Mehdi, Milanifard, Maryam, Nabiuni, Sana, Nabiuni, Hosna. (1402). 'The Impact of Social Networks on Enhancing Safety and Efficacy Outcomes in Low-Dose Rituximab Treatment for Central Nervous System Demyelinating Diseases', سامانه مدیریت نشریات علمی, 14(3), pp. 206-215. doi: 10.30476/ijvlms.2023.99354.1240
Nabiuni, Mohsen, Mokhtari, Mahisa, Hatam, Jaber, Emamikhah, Maziar, Abolmaali, Meysam, Amini, Elaheh, Saiyarsarai, Parisa, Moghaddasi, Mehdi, Milanifard, Maryam, Nabiuni, Sana, Nabiuni, Hosna. The Impact of Social Networks on Enhancing Safety and Efficacy Outcomes in Low-Dose Rituximab Treatment for Central Nervous System Demyelinating Diseases. سامانه مدیریت نشریات علمی, 1402; 14(3): 206-215. doi: 10.30476/ijvlms.2023.99354.1240

The Impact of Social Networks on Enhancing Safety and Efficacy Outcomes in Low-Dose Rituximab Treatment for Central Nervous System Demyelinating Diseases

Interdisciplinary Journal of Virtual Learning in Medical Sciences
مقاله 4، دوره 14، شماره 3 - شماره پیاپی 54، آذر 2023، صفحه 206-215    اصل مقاله (537.55 K)
نوع مقاله: Original Article
شناسه دیجیتال (DOI): 10.30476/ijvlms.2023.99354.1240
نویسندگان
Mohsen Nabiuni1؛ Mahisa Mokhtari2؛ Jaber Hatam3؛ Maziar Emamikhah4؛ Meysam Abolmaali5؛ Elaheh Amini4؛ Parisa Saiyarsarai6، 7؛ Mehdi Moghaddasi* 4؛ Maryam Milanifard8؛ Sana Nabiuni9؛ Hosna Nabiuni10
1Assistant Professor and Chief of Neurosurgery Department, School of Medicine, Iran University of Medical Sciences, Tehran, Iran
2Assistant Professor of Neurology Department, School of Medicine, Iran University of Medical Sciences, Tehran, Iran
3Assistant Professor of Neurosurgery Department, School of Medicine, Iran University of Medical Sciences, Tehran, Iran
4Department of Neurology, Rasool-e Akram Hospital, School of Medicine, Iran University of Medical Sciences, Tehran, Iran
5Shefa Neuroscience Research Center, Khatam Al Anbia Hospital, Tehran, Iran
6Department of Pharmacoeconomics and Pharmaceutical Administration, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
7The Institute of Pharmaceutical Sciences, Tehran University of Medical Sciences, Tehran, Iran
8Department of Anatomical Sciences, School of Medicine, Iran university of Medical Sciences, Tehran, Iran
9Pharmacist, University College London, England, London
10Medical Student, Iran university of Medical Sciences, Tehran, Iran
چکیده
Background: In the realm of healthcare, the symbiotic relationship between social networks and medical advancements has attracted significant attention. This study aimed to explore the effectiveness and safety of this approach, with a particular focus on the role of social networks in disseminating information and shaping patient experiences.
Methods: In a prospective single-arm interventional study, we examined the effects of integrating social networks – Skype and WhatsApp – to enhance the safety and efficacy outcomes of low-dose Rituximab treatment for CNS Demyelinating Diseases. Patients eligible for treatment were recruited, and ethical consent was secured. The intervention involved informative Skype groups, led by medical experts, providing education and follow-up, and WhatsApp groups for peer support and question-answer sessions. Clinical data and interaction metrics were collected to evaluate treatment outcomes and engagement levels. 
Results: A total of 99 patients received rituximab, with 42 diagnosed with RRMS, 43 with SPMS, and 14 with NMOSD. The treatment period ranged from 12 to 40 months. Among the RRMS patients, 8 (19%) experienced new attacks, while 10 (23%) of the SPMS patients and 1 (7%) of the NMOSD patients had new attacks. In cases of RRMS and NMOSD, there was a decrease in EDSS scores. Additionally, SPMS and NMOSD patients showed a decrement in serum IgG levels. Two cases of drug adverse events were reported. Mean EDSS variability had a decrease in RRMS (-0.32, P=0.06) and NMOSD (-0.57, P=0.004) and had a slight increase among patients with SPMS (+0.19, P=0.23).
Conclusion: Recognizing the impact of social networks can lead to improved patient care and tailored support systems.
کلیدواژه‌ها
Distance؛ Social networking؛ Teaching؛ Multiple sclerosis
مراجع
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