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The Role of Medicinal Plants in Diabetes Mellitus and Oxidative Stress: A Review | ||
| International Journal of Nutrition Sciences | ||
| مقاله 2، دوره 8، شماره 2، شهریور 2023، صفحه 74-83 اصل مقاله (414.89 K) | ||
| نوع مقاله: Review Article | ||
| شناسه دیجیتال (DOI): 10.30476/ijns.2023.97688.1217 | ||
| نویسندگان | ||
| Emuesiri Goodies Moke* 1؛ Emuesiri Kohworho Umukoro2؛ Sinodukoo Eziuzo Okafo3؛ Jerome Ndudi Asiwe4؛ Anthony Taghogho Eduviere1؛ Lisa Iziegbe Omorodion1، 5؛ Earnest Oghenesuvwe Erhirhie6؛ Adaeze Phina Uchendu7؛ Nkechi Precious Isibor1؛ Ruth Eboye1 | ||
| 1Department of Pharmacology, Faculty of Basic Medical Sciences, Delta State University, Abraka, Nigeria | ||
| 2Department of Pharmacology and Therapeutics, Faculty of Basic Clinical Sciences, Delta State University, Abraka, Nigeria | ||
| 3Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Delta State University, Abraka, Nigeria | ||
| 4Department of Human Physiology, Faculty of Basic Medical Sciences, Delta State University, Abraka, Nigeria | ||
| 5Graduate Program in Pharmacology and Drug Development, Graduate School of Biomedical Sciences, School of Medicine, Tufts University, Boston, MA, USA | ||
| 6Department of Pharmacology and Toxicology, Faculty of Pharmaceutical Sciences, Chukwuemeka Odumegwu Ojukwu University, Igbariam, Anambra State, Nigeria | ||
| 7Department of Pharmacology and Toxicology, Faculty of Pharmacy, University of Benin, Benin City, Nigeria | ||
| چکیده | ||
| Diabetes mellitus is an endocrinology disorder of great global concern. It results from an irregularity in the secretion or action of insulin. It is a metabolic condition characterized by chronic hyperglycemia. Oxidative stress plays a critical role in the pathophysiology of some diseases such as diabetes, aging, cancer, cardiovascular disease, as well as liver and lung diseases. Oxidative stress occurs due to an imbalance between radical generation and radical scavenging. One of the main mechanisms for the development of diabetes complications is via oxidative stress. Oxidative stress is a main upstream occurrence for diabetes complications as well as the development of insulin resistivity. Medicinal plants can be useful in the treatment of numerous diseases and some of their healthful effects are due to their antioxidant activity. Their antihyperglycemic effect is very much linked to their antioxidant potential. This review summarized the antidiabetic potential of some medicinal plants in animal models. There is a continuous need to explore the medicinal capability of herbal products with antioxidant effects in the management of diabetes mellitus. | ||
| کلیدواژه‌ها | ||
| Medicinal plants؛ Herbals؛ Phytochemicals؛ Antioxidant؛ Diabetes | ||
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آمار تعداد مشاهده مقاله: 1,486 تعداد دریافت فایل اصل مقاله: 751 |
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