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Current Speculations on the Low Incidence Rate of the COVID-19 among Children | ||
| International Journal of School Health | ||
| مقاله 8، دوره 7، شماره 2 - شماره پیاپی 25، تیر 2020، صفحه 61-62 اصل مقاله (162.28 K) | ||
| نوع مقاله: Letter to Editor | ||
| شناسه دیجیتال (DOI): 10.30476/intjsh.2020.85997.1066 | ||
| نویسندگان | ||
| Dana Khdr Sabir1؛ Karzan R Sidiq1، 2؛ Shakhawan M Ali* 3 | ||
| 1Department of Medical Laboratory Sciences, Charmo University, 46023, Chamchamal, Sulaimani, Kurdistan Region, Iraq | ||
| 2Charmo Centre for Research, Training and Consultancy, Charmo University, 46023 Chamchamal, Sulaimani, Kurdistan Region, Iraq | ||
| 3Department of Oral and Maxillofacial Surgery, School of Medicine, Faculty of Dentistry, University of Sulaimani, Kurdistan Region, Iraq | ||
| چکیده | ||
| First reported in Wuhan, China on December 2019, the coronavirus disease 2019 (COVID-19) is a contagious viral infection of the respiratory system caused by SARS-CoV-2 (1). As of April 26, 2020, more than 2.5 million people have contracted the disease with nearly 200,000 deaths (2). The data published on the mortality and morbidity of the disease suggest that children under 10 years of age are generally less vulnerable to the virus and are usually asymptomatic or show milder symptoms (3). On the other hand, adults and the elderly, particularly those with underlying health conditions, appear to be more susceptible to the disease (4). It is not clear why children are more immune to COVID-19. However, we have an idea which we would like to share with the general public and scientific communities, hoping this would hinder the further spread of the disease. | ||
| کلیدواژه‌ها | ||
| COVID-19؛ SARS-CoV-2؛ Children؛ Immunity؛ Immunization؛ Vaccination | ||
| مراجع | ||
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1. Zhu N, Zhang D, Wang W, Li X, Yang B1, Song J, et al.. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med.2020; 20;382(8):727-733. doi: 10.1056/NEJMoa2001017. [PMID: 31978945]; [PubMed Central: PMC7092803]. ## 2. World Health Organization, Coronavirus disease 2019 (COVID-19): situation report, Situation report- 97. 2020. ## 3. Brodin P. Why is COVID-19 so mild in children?. Acta Paediatr. 2020;04.001,(2020)doi:10.1111/apa.15271 4. Zhonghua Liu Xing Bing Xue Za Zhi. The epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases (COVID-19) in China. Bing Xue Za Zhi. 2020. 41(2):145-151. doi:10.3760/cma.j.issn.0254-6450.2020.02.003. [PubMed: 32064853]. ## 5. Ahmed, S.F., A.A. Quadeer, M.R. McKay, Preliminary Identification of Potential Vaccine Targets for the COVID-19 Coronavirus (SARS-CoV-2) Based on SARS-CoV Immunological Studies. Viruses, 2020; 12(3). [PubMed: 32106567]. [PubMed Central:PMC7150947]. ## 6. Ahmadpoor P, L, Rostaing, Why the immune system fails to mount an adaptive immune response to a Covid-19 infection. Transplant International, 2020. doi: 10.1111/tri.13611. ## 7. Fan Wu, Aojie Wang, Mei Liu, Qimin Wang, Jun Chen, Shuai Xia, et al. Neutralizing antibody responses to SARS-CoV-2 in a COVID-19 recovered patient cohort and their implications. medRxiv. doi: 10.1101/2020.03.30.20047365. ## 8. Thapa, P. and D.L. Farber, The Role of the Thymus in the Immune Response. Thorac Surg Clin, 2019; 29(2):123-131. doi: 10.1016/j.thorsurg.2018.12.001. [PubMed: 32106567]. [PubMed Central: PMC6446584]. ## 9. Atabani SF, Obeid OE, Chargelegue D, Aaby P, Whittle H, Steward MW. Identification of an immunodominant neutralizing and protective epitope from measles virus fusion protein by using human sera from acute infection. J Virol, 1997; 71(10): 7240-5. [PMID: 9311797]; [PubMed Central: PMC192064] ## 10. Medina, R. A, Manicassamy, B, Stertz, S, Seibert, C. W, Hai, R, Belshe, R. B, et al. Pandemic 2009 H1N1 vaccine protects against 1918 Spanish influenza virus. Nat Commun, 2010; 1(3),28. 10.1038/ncomms1026 (2010). ## | ||
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