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Yazdanpanah, Mohammad Javad, Sharifi Sistani, Noorieh, Hosseini, Elnaz, Vosoughi, Elham, Hosseini, Seyed Saeid, Khajedaluee, Mohammad, Amel Jamehdar, Saeid. (1399). Assessment of the Relationship between Human Papilloma Virus Infections and Cutaneous Squamous Cell Carcinoma. سامانه مدیریت نشریات علمی, 11(2), 185-191. doi: 10.30476/mejc.2019.78660.0
Mohammad Javad Yazdanpanah; Noorieh Sharifi Sistani; Elnaz Hosseini; Elham Vosoughi; Seyed Saeid Hosseini; Mohammad Khajedaluee; Saeid Amel Jamehdar. "Assessment of the Relationship between Human Papilloma Virus Infections and Cutaneous Squamous Cell Carcinoma". سامانه مدیریت نشریات علمی, 11, 2, 1399, 185-191. doi: 10.30476/mejc.2019.78660.0
Yazdanpanah, Mohammad Javad, Sharifi Sistani, Noorieh, Hosseini, Elnaz, Vosoughi, Elham, Hosseini, Seyed Saeid, Khajedaluee, Mohammad, Amel Jamehdar, Saeid. (1399). 'Assessment of the Relationship between Human Papilloma Virus Infections and Cutaneous Squamous Cell Carcinoma', سامانه مدیریت نشریات علمی, 11(2), pp. 185-191. doi: 10.30476/mejc.2019.78660.0
Yazdanpanah, Mohammad Javad, Sharifi Sistani, Noorieh, Hosseini, Elnaz, Vosoughi, Elham, Hosseini, Seyed Saeid, Khajedaluee, Mohammad, Amel Jamehdar, Saeid. Assessment of the Relationship between Human Papilloma Virus Infections and Cutaneous Squamous Cell Carcinoma. سامانه مدیریت نشریات علمی, 1399; 11(2): 185-191. doi: 10.30476/mejc.2019.78660.0

Assessment of the Relationship between Human Papilloma Virus Infections and Cutaneous Squamous Cell Carcinoma

Middle East Journal of Cancer
مقاله 7، دوره 11، شماره 2 - شماره پیاپی 42، تیر 2020، صفحه 185-191    اصل مقاله (869.92 K)
نوع مقاله: Original Article(s)
شناسه دیجیتال (DOI): 10.30476/mejc.2019.78660.0
نویسندگان
Mohammad Javad Yazdanpanah1؛ Noorieh Sharifi Sistani2؛ Elnaz Hosseini1؛ Elham Vosoughi1؛ Seyed Saeid Hosseini3؛ Mohammad Khajedaluee4؛ Saeid Amel Jamehdar* 5
1Cutaneous Leishmaniasis Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
2Department of Pathology, Ghaem Hospital, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
3Department of Otorhinolaryngology, Ghaem Hospital, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
4Department of Biostatistics and Epidemiology, School of Health, Mashhad University of Medical Sciences, Mashhad, Iran
5Cancer Molecular Pathology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
چکیده
Background: The relationship between HPV infection and skin squamous cell carcinoma (SCC) development in immunocompetent individuals is unclear. Therefore, the purpose of this study was to assess the association between HPV infection and skin SCC.
Methods: HPV DNA prevalence was evaluated in the paraffin embedded specimens of 70 immunocompetent patients, of which 35 patients had skin SCC and 35 had normal skin. PCR technique and GP6/5 primers were utilized for HPV DNA detection.
Result: Based on this study, 14.3% of the cases (5 of 35, 2 with low risk and 3 with high risk viruses) and 2.9% of the controls (1 of 35 with low risk virus) had papilloma viruses. However, there was no significant statistical relationship between the HPV DNA presence and the SCC development in skin.
Conclusion: The direct effect of HPV on skin cancerogenesis remains questionable.
کلیدواژه‌ها
Human papilloma virus؛ Non-melanoma skin cancers؛ Squamous cell carcinoma
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