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Prognostic Nutritional Index as a Predictor of Postoperative Outcome in Patients with Gastrointestinal Malignancies | ||
| International Journal of Nutrition Sciences | ||
| مقاله 8، دوره 10، شماره 1، فروردین 2025، صفحه 74-80 اصل مقاله (584.59 K) | ||
| نوع مقاله: Original Article | ||
| شناسه دیجیتال (DOI): 10.30476/ijns.2025.102597.1324 | ||
| نویسندگان | ||
| Udayanilavan Padmanaban1؛ Avinash Ramakrishnan2؛ Abhinaya Reddy* 2؛ Rajeshwari Murugesan3؛ Chilaka Suresh2؛ Uday Shamrao Kumbhar2؛ Ankit Jain2؛ Sreenath Gubbi Shamanna2 | ||
| 1Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India | ||
| 2Department of Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India | ||
| 3Department of Biostatistics, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India | ||
| چکیده | ||
| Background: Nutritional status of patients plays an important role in post-operative recovery. A preoperative index can help predict the post-operative morbidity and in optimizing the patient’s status. This study was done to evaluate the usefulness of prognostic nutritional index (PNI) in identifying patients who are at high risk for developing postoperative morbidity. Methods: In a retrospective study, data were collected from databases during January 2019 and December 2022 by including all patients who underwent surgery for gastrointestinal malignancies with a curative intent. Univariate and multiple logistic analyses were performed to evaluate the factors which affect the postoperative morbidity. Results: Data of 182 patients was retrieved from the database. Stomach carcinoma was the most common gastrointestinal cancer of our study. Surgical site infection was the most common complication noted among 33.5% (n=61) of patients. On univariate analysis of the factors which contributed to post-operative morbidity, PNI and American Society of Anaesthesiologists score was found to be significant in assessments. On multiple regression analysis, only PNI was found to be helpful in predicting postoperative morbidity. The area under curve for predicting the postoperative complications in our study was 0.608 (95%CI, 0.525-0.690, p=0.012). The cut-off value of PNI was 72.9 with a sensitivity and specificity of 62% and 53.3%. Conclusion: Encouraging the routine use of PNI in preoperative assessments for patients undergoing gastrointestinal cancer surgery can potentially lead to a better risk stratification, more targeted perioperative management, and ultimately improved surgical outcome. | ||
| کلیدواژه‌ها | ||
| Prognostic nutritional index؛ Gastrointestinal malignancies؛ Postoperative outcome؛ Cancer؛ Nutrition | ||
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آمار تعداد مشاهده مقاله: 36,849 تعداد دریافت فایل اصل مقاله: 18 |
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