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Aitmagambetova, Marzhan, Tulyayeva, Anar, Koishybaev, Arip, Zholdybayeva, Elena, Balmagambetova, Saule, Kereyeva, Nurgul, Zholmukhamedova, Dinara, Ablakimova, Nurgul. (1403). The First CDH1 Gene Mutation Gastric Cancer Case in Kazakhstan: Implications for Genetic Screening; A Letter to the Editor. سامانه مدیریت نشریات علمی, 50(3), 199-201. doi: 10.30476/ijms.2025.104223.3778
Marzhan Aitmagambetova; Anar Tulyayeva; Arip Koishybaev; Elena Zholdybayeva; Saule Balmagambetova; Nurgul Kereyeva; Dinara Zholmukhamedova; Nurgul Ablakimova. "The First CDH1 Gene Mutation Gastric Cancer Case in Kazakhstan: Implications for Genetic Screening; A Letter to the Editor". سامانه مدیریت نشریات علمی, 50, 3, 1403, 199-201. doi: 10.30476/ijms.2025.104223.3778
Aitmagambetova, Marzhan, Tulyayeva, Anar, Koishybaev, Arip, Zholdybayeva, Elena, Balmagambetova, Saule, Kereyeva, Nurgul, Zholmukhamedova, Dinara, Ablakimova, Nurgul. (1403). 'The First CDH1 Gene Mutation Gastric Cancer Case in Kazakhstan: Implications for Genetic Screening; A Letter to the Editor', سامانه مدیریت نشریات علمی, 50(3), pp. 199-201. doi: 10.30476/ijms.2025.104223.3778
Aitmagambetova, Marzhan, Tulyayeva, Anar, Koishybaev, Arip, Zholdybayeva, Elena, Balmagambetova, Saule, Kereyeva, Nurgul, Zholmukhamedova, Dinara, Ablakimova, Nurgul. The First CDH1 Gene Mutation Gastric Cancer Case in Kazakhstan: Implications for Genetic Screening; A Letter to the Editor. سامانه مدیریت نشریات علمی, 1403; 50(3): 199-201. doi: 10.30476/ijms.2025.104223.3778

The First CDH1 Gene Mutation Gastric Cancer Case in Kazakhstan: Implications for Genetic Screening; A Letter to the Editor

Iranian Journal of Medical Sciences
مقاله 8، دوره 50، شماره 3، خرداد 2025، صفحه 199-201    اصل مقاله (1.36 M)
نوع مقاله: Letter(s) to the Editor
شناسه دیجیتال (DOI): 10.30476/ijms.2025.104223.3778
نویسندگان
Marzhan Aitmagambetova1؛ Anar Tulyayeva1؛ Arip Koishybaev1؛ Elena Zholdybayeva2؛ Saule Balmagambetova1؛ Nurgul Kereyeva1؛ Dinara Zholmukhamedova1؛ Nurgul Ablakimova* 3، 4
1Department of Oncology, West Kazakhstan Marat Ospanov Medical University, Aktobe, Kazakhstan
2National Center for Biotechnology, Astana, Kazakhstan
3Department of Pharmacology, West Kazakhstan Marat Ospanov Medical University, Aktobe, Kazakhstan
4Department of Hospital Pharmacy, Regional Perinatal Center, Aktobe, Kazakhstan
چکیده
Despite significant advances in medicine, food preservation methods, and Helicobacter pylori (H. pylori) treatment, gastric cancer remains the fifth most common type of cancer and the fourth leading cause of cancer-related deaths worldwide, accounting for over a million new cases and nearly 770,000 deaths in 2020.
کلیدواژه‌ها
E-cadherin؛ Gastric carcinoma؛ Heredity؛ Genetic predisposition
مراجع
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  2. Corso G, Magnoni F, Massari G, Trovato CM, De Scalzi AM, Vicini E, et al. CDH1 germline mutations in healthy individuals from families with the hereditary diffuse gastric cancer syndrome. J Med Genet. 2022;59:313-7. doi: 10.1136/jmedgenet-2021-108226. PubMed PMID: 34952833.
  3. Li J. Gastric Cancer in Young Adults: A Different Clinical Entity from Carcinogenesis to Prognosis. Gastroenterol Res Pract. 2020;2020:9512707. doi: 10.1155/2020/9512707. PubMed PMID: 32190044; PubMed Central PMCID: PMCPMC7071806.
  4. Luo W, Fedda F, Lynch P, Tan D. CDH1 Gene and Hereditary Diffuse Gastric Cancer Syndrome: Molecular and Histological Alterations and Implications for Diagnosis And Treatment. Front Pharmacol. 2018;9:1421. doi: 10.3389/fphar.2018.01421. PubMed PMID: 30568591; PubMed Central PMCID: PMCPMC6290068.
  5. Moehler M, Al-Batran SE, Andus T, Arends J, Arnold D, Baretton G, et al. S3-Leitlinie Magenkarzinom – Diagnostik und Therapie der Adenokarzinome des Magens und des ösophagogastralen Übergangs – Langversion 2.0 – August 2019. AWMF-Registernummer: 032/009OL. Z Gastroenterol. 2019;57:1517-632. doi: 10.1055/a-1018-2516. PubMed PMID: 31826284.
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تعداد مشاهده مقاله: 50
تعداد دریافت فایل اصل مقاله: 41


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