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Spontaneous Hemoperitoneum Caused by Malignant Gastrointestinal Stromal Tumor: A Case Report | ||
Iranian Journal of Medical Sciences | ||
مقاله 7، دوره 50، شماره 2، اردیبهشت 2025، صفحه 124-128 اصل مقاله (1.32 M) | ||
نوع مقاله: Case Report(s) | ||
شناسه دیجیتال (DOI): 10.30476/ijms.2024.104038.3751 | ||
نویسندگان | ||
Nivetha Munuswamy1؛ Pola Govardhan Kumar* 1؛ Rajendran Shanmugasundaram2؛ Sreedevi B. Venkatesh1 | ||
1Department of General Surgery, Sree Balaji Medical College and Hospital, Chennai, India | ||
2Department of Surgical Gastroenterology, Sree Balaji Medical College and Hospital, Chennai, India | ||
چکیده | ||
Gastrointestinal stromal tumors (GIST) are less prevalent mesenchymal tumors, accounting for 1% of gastrointestinal malignancies. Spontaneous hemoperitoneum (SH) following gastric GIST rupture is a rare occurrence. The present study described a case of a 67-year-old female who presented with acute onset abdominal pain. Vital signs at the time of presentation were unstable. Contrast-enhanced computed tomography (CECT) of the abdomen revealed a mixed-density mass lesion with multiple hyperdense areas within. A hemogram indicated a low hemoglobin level. An emergency laparotomy revealed a ruptured pedunculated, friable mass with active bleeding arising from the lesser curvature of the stomach. A wedge resection was carried out to achieve a gross negative margin of the mass. Final pathology confirmed GIST epitheloid type with positive margins (pT3N0M0-pathologically tumor size within 10 cm with no nodal or distant metastasis) and positive for CD117, DOG1. Given the tumor rupture and positive margins, the patient was started on imatinib mesylate therapy. As demonstrated in this case, GIST rarely ruptures, resulting in hemoperitoneum. The primary treatment approach is surgical exploration and resection. | ||
کلیدواژهها | ||
Gastrointestinal stromal tumors؛ Hemoperitoneum؛ Rupture | ||
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