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Mehdizadeh, Mohammad, Lotfi, Ali, Atarbashi-Moghadam, Saede, Eftekhari-Moghadam, Parsa. (1403). Mandibular Metastatic Breast Cancer: A Rare Case Report with Diagnostic Challenge. سامانه مدیریت نشریات علمی, (), -. doi: 10.30476/dentjods.2025.103764.2475
Mohammad Mehdizadeh; Ali Lotfi; Saede Atarbashi-Moghadam; Parsa Eftekhari-Moghadam. "Mandibular Metastatic Breast Cancer: A Rare Case Report with Diagnostic Challenge". سامانه مدیریت نشریات علمی, , , 1403, -. doi: 10.30476/dentjods.2025.103764.2475
Mehdizadeh, Mohammad, Lotfi, Ali, Atarbashi-Moghadam, Saede, Eftekhari-Moghadam, Parsa. (1403). 'Mandibular Metastatic Breast Cancer: A Rare Case Report with Diagnostic Challenge', سامانه مدیریت نشریات علمی, (), pp. -. doi: 10.30476/dentjods.2025.103764.2475
Mehdizadeh, Mohammad, Lotfi, Ali, Atarbashi-Moghadam, Saede, Eftekhari-Moghadam, Parsa. Mandibular Metastatic Breast Cancer: A Rare Case Report with Diagnostic Challenge. سامانه مدیریت نشریات علمی, 1403; (): -. doi: 10.30476/dentjods.2025.103764.2475

Mandibular Metastatic Breast Cancer: A Rare Case Report with Diagnostic Challenge

Journal of Dentistry
مقالات آماده انتشار، پذیرفته شده، انتشار آنلاین از تاریخ 30 دی 1403    اصل مقاله (683.44 K)
نوع مقاله: Case Report
شناسه دیجیتال (DOI): 10.30476/dentjods.2025.103764.2475
نویسندگان
Mohammad Mehdizadeh1؛ Ali Lotfi2؛ Saede Atarbashi-Moghadam* 2؛ Parsa Eftekhari-Moghadam3
1Dept. of Oral and Maxillofacial Surgery, School of Dentistry, Qom University of Medical Sciences, Qom, Iran.
2Dept. of Oral and Maxillofacial Pathology, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
3Undergraduate Student, Research Committee, School of Dentistry, Shahid Beheshti, University of Medical Sciences, Tehran, Iran.
چکیده
Jawbone metastatic lesions are a diagnostic challenge because of their rarity and variable clinical, radiographic, and histopathologic characteristics. This paper presents a 57-year-old female with a chief complaint of lower face swelling. Cone beam computed tomography (CBCT) showed a multilocular radiolucency with right angle septa in the left mandibular area with cortical destruction. She had a history of right breast cancer about six years ago. Histopathologic examination revealed sheets of malignant small round cells. Immunohistochemistry (IHC) was only positive for cytokeratin (CK) and GATA3. CA15-3 tumor marker was higher than the normal range. Based on the aforementioned data, the diagnosis of metastatic breast carcinoma was performed. The whole-body and computed tomography (CT) scan showed just involvement in the left mandibular area. The radiographic appearance of metastatic lesions might be misleading, and microscopic sections might be poorly differentiated, therefore, a precise past medical history, IHC staining, and tumor markersre valuable issues in diagnosing oral cavity metastasis.
کلیدواژه‌ها
Metastasis؛ Breast cancer؛ Mandible؛ Oral cavity
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