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Zamani, Amirhossein, Alipour, Aida, Zarshenas, Mohammad M., Ashrafi, Hajar. (1403). Design and Preparing a Topical Semi-solid Formulation of a Combination of Plantago ovata seeds and Rosehip oil to Provide an Analgesic and Anti-inflammatory Medicine. سامانه مدیریت نشریات علمی, 10(4), 343-354. doi: 10.30476/tips.2025.104471.1264
Amirhossein Zamani; Aida Alipour; Mohammad M. Zarshenas; Hajar Ashrafi. "Design and Preparing a Topical Semi-solid Formulation of a Combination of Plantago ovata seeds and Rosehip oil to Provide an Analgesic and Anti-inflammatory Medicine". سامانه مدیریت نشریات علمی, 10, 4, 1403, 343-354. doi: 10.30476/tips.2025.104471.1264
Zamani, Amirhossein, Alipour, Aida, Zarshenas, Mohammad M., Ashrafi, Hajar. (1403). 'Design and Preparing a Topical Semi-solid Formulation of a Combination of Plantago ovata seeds and Rosehip oil to Provide an Analgesic and Anti-inflammatory Medicine', سامانه مدیریت نشریات علمی, 10(4), pp. 343-354. doi: 10.30476/tips.2025.104471.1264
Zamani, Amirhossein, Alipour, Aida, Zarshenas, Mohammad M., Ashrafi, Hajar. Design and Preparing a Topical Semi-solid Formulation of a Combination of Plantago ovata seeds and Rosehip oil to Provide an Analgesic and Anti-inflammatory Medicine. سامانه مدیریت نشریات علمی, 1403; 10(4): 343-354. doi: 10.30476/tips.2025.104471.1264

Design and Preparing a Topical Semi-solid Formulation of a Combination of Plantago ovata seeds and Rosehip oil to Provide an Analgesic and Anti-inflammatory Medicine

Trends in Pharmaceutical Sciences
مقاله 7، دوره 10، شماره 4، اسفند 2024، صفحه 343-354    اصل مقاله (506.98 K)
نوع مقاله: Original Article
شناسه دیجیتال (DOI): 10.30476/tips.2025.104471.1264
نویسندگان
Amirhossein Zamani1، 2؛ Aida Alipour1، 2؛ Mohammad M. Zarshenas* 3؛ Hajar Ashrafi4
1Student Research Committee, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.
2Medicinal Plants Processing Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
3Department of Phytopharmaceuticals (Traditional Pharmacy), School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.
4Department of Pharmaceutics, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.
چکیده
Considering the importance of pain, this study aims to present a standard topical formulation for pain control. In the texts of traditional Persian pharmaceutical books, many verbs, and citrus fruits are mentioned as pain relievers. In this study, the Plantago ovata Forsk. plant was selected from the book of Makhzen al-Adviyah, and related aqueous and acidic extractions were yielded in rose oil. After microscopic characterization and determining the identification number of the plant and FTIR test, Plantago ovata Forsk seed extract was prepared with different acidic and aqueous types, and the mucilage was prepared after evaluating several cream formulations, finally, the proportion of 70% oil and 30% stearic acid contained 65% extract. It was chosen as the appropriate formulation, which was more suitable for appearance characteristics (uniform texture and proper spreading without feeling rough on the skin). The final semi-solid formulation was examined in terms of the uniformity and integrity of the cream and the examination of rubability and cream consistency tests, the examination of spreadability, pH measurement, and the examination of viscosity and rheology properties, and the results showed that this formulation in terms of pharmaceutics tests and the total saccharide content was in the acceptable range. After passing the clinical trials, the mentioned product can be effective as a product derived from herbal compounds for pain control.

تازه های تحقیق

Mohammad M. Zarshenas (Google Scholar)

Hajar Ashrafi (Google Scholar)

کلیدواژه‌ها
Analgesic؛ Medicinal plants؛ Pain؛ Topical
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