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Alipanah, Maryam, Yousefi, Gholamhossein, Sobhani, Zahra, Jahromi, Mohammad Ali, Zarshenas, Mohammad. (1403). Design, formulation and antimicrobial assessment of a traditional Iranian antiperspirant formula from Rosa damascena flowers and Myrtus communis leaves.. سامانه مدیریت نشریات علمی, 10(4), 299-312. doi: 10.30476/tips.2024.103236.1247
Maryam Alipanah; Gholamhossein Yousefi; Zahra Sobhani; Mohammad Ali Farboodniay Jahromi; Mohammad Mehdi Zarshenas. "Design, formulation and antimicrobial assessment of a traditional Iranian antiperspirant formula from Rosa damascena flowers and Myrtus communis leaves.". سامانه مدیریت نشریات علمی, 10, 4, 1403, 299-312. doi: 10.30476/tips.2024.103236.1247
Alipanah, Maryam, Yousefi, Gholamhossein, Sobhani, Zahra, Jahromi, Mohammad Ali, Zarshenas, Mohammad. (1403). 'Design, formulation and antimicrobial assessment of a traditional Iranian antiperspirant formula from Rosa damascena flowers and Myrtus communis leaves.', سامانه مدیریت نشریات علمی, 10(4), pp. 299-312. doi: 10.30476/tips.2024.103236.1247
Alipanah, Maryam, Yousefi, Gholamhossein, Sobhani, Zahra, Jahromi, Mohammad Ali, Zarshenas, Mohammad. Design, formulation and antimicrobial assessment of a traditional Iranian antiperspirant formula from Rosa damascena flowers and Myrtus communis leaves.. سامانه مدیریت نشریات علمی, 1403; 10(4): 299-312. doi: 10.30476/tips.2024.103236.1247

Design, formulation and antimicrobial assessment of a traditional Iranian antiperspirant formula from Rosa damascena flowers and Myrtus communis leaves.

Trends in Pharmaceutical Sciences
مقاله 4، دوره 10، شماره 4، اسفند 2024، صفحه 299-312    اصل مقاله (639.44 K)
نوع مقاله: Original Article
شناسه دیجیتال (DOI): 10.30476/tips.2024.103236.1247
نویسندگان
Maryam Alipanah1، 2؛ Gholamhossein Yousefi3؛ Zahra Sobhani4؛ Mohammad Ali Farboodniay Jahromi* 2؛ Mohammad Mehdi Zarshenas* 5، 2
1Department of Phytopharmaceuticals (Traditional Pharmacy), School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.
2Medicinal Plants Processing Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
3Department of Pharmaceutics, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.
4Department of Quality Control, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.
5Department of Phytopharmacuticals (Traditional Pharmacy), School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.
چکیده
This study deals with the design and preparation of an antiperspirant formulation from traditional Iranian medicine containing aqueous decoctions of Rosa damascena Mill flowers and Myrtus communis L. leaves. The resulting product was evaluated for phytochemical content as well as physical, macroscopic, and rheological characteristics. Total tannin, total phenol, and total flavonoid contents were determined using standard spectrophotometric methods. The dilution method was used to reduce the concentration of antimicrobial protective components in the formulation and neutralize any residual activity. Most of the resulting formulated suspension products showed consistency in texture, a light brown appearance, and a pH value of 5.15. The total phenol content of R. damascena flower extract was determined as 219.1±3.42 mg GAE/g (mg gallic acid equivalent/gram of extract), and those of M. communis leaf extract and the final product were found to be 361.15±1.61 and 306.69 ±0.43 mg GAE/g respectively. Total flavonoid was 10.83±0.83 mg QE/g (mg quercetin equivalent/gram of extract) for R. damascena flower extract, 19.66±0.08 mg QE/g for M. Communis leaf extract, and 18.92±0.66 mg QE/g for the final product. The total tannin content of R. damascena flower extract was 137.92±1.17 mg QE/g, and those of M. communis leaf extract and the final product were 78.37±0.29 and 107.72±1.28 mg TA/g (mg tannic acid equivalent per gram of extract) respectively. The microbial threshold of the product was found to be quite perfectly within the permissible limit. Following pharmacopoeial and quality control assessments, the present formulation can be considered as a new health-therapeutic natural alternative for treating hyperhidrosis disorders.

تازه های تحقیق

Zahra Sobhani (Google Scholar)

Mohammad Ali Farboodniay Jahromi (Google Scholar)

کلیدواژه‌ها
Antiperspirant formulation؛ Rosa damascena؛ Myrtus communis
مراجع
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