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Zheng, Jie, Luo, Gang, Deng, Ming Ming. (1403). Clinical Analysis of Sinistral Portal Hypertension. سامانه مدیریت نشریات علمی, 49(8), 487-493. doi: 10.30476/ijms.2023.99570.3164
Jie Zheng; Gang Luo; Ming Ming Deng. "Clinical Analysis of Sinistral Portal Hypertension". سامانه مدیریت نشریات علمی, 49, 8, 1403, 487-493. doi: 10.30476/ijms.2023.99570.3164
Zheng, Jie, Luo, Gang, Deng, Ming Ming. (1403). 'Clinical Analysis of Sinistral Portal Hypertension', سامانه مدیریت نشریات علمی, 49(8), pp. 487-493. doi: 10.30476/ijms.2023.99570.3164
Zheng, Jie, Luo, Gang, Deng, Ming Ming. Clinical Analysis of Sinistral Portal Hypertension. سامانه مدیریت نشریات علمی, 1403; 49(8): 487-493. doi: 10.30476/ijms.2023.99570.3164

Clinical Analysis of Sinistral Portal Hypertension

Iranian Journal of Medical Sciences
مقاله 3، دوره 49، شماره 8، آبان 2024، صفحه 487-493    اصل مقاله (825.56 K)
نوع مقاله: Original Article(s)
شناسه دیجیتال (DOI): 10.30476/ijms.2023.99570.3164
نویسندگان
Jie Zheng؛ Gang Luo؛ Ming Ming Deng*
Department of Gastroenterology, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan 646000, China
چکیده
Background: Sinistral portal hypertension (SPH) is the only type of portal hypertension that is entirely curable. However, it can easily cause varicose veins in the esophagus and/or stomach, as well as upper gastrointestinal hemorrhage. This study aimed to investigate the clinical characteristics and treatments of sinistral portal hypertension. 
Methods: All patients with pancreatic disease were included in this retrospective cohort study at the Affiliated Hospital of Southwest Medical University (Luzhou, China) from September 2019 to September 2021. The required information including the patient’s demographics, serum laboratory indicators, imaging and endoscopy examinations, and clinical features were gathered and evaluated. The results were expressed as numbers and percentages.
Results: Out of the 830 patients with pancreatic diseases, 61 (7.3%) developed SPH. The most common cause of SPH was acute pancreatitis (80.3%), followed by chronic pancreatitis (11.5%). The splenic vein was the most frequently affected vein in patients (45/61, 73.8%). The findings of the contrast-enhanced computed tomography (CECT) indicated that  51 cases (83.6%) had gastric fundal-body varices, and three cases had combined gastric and esophageal varices. In the perigastric collateral channel formation, gastroepiploic varices (43/61, 70.5%) most frequently occurred in patients with SPH. Splenomegaly was a prevalent manifestation in SPH patients (45.9%). Five cases had gastrointestinal variceal hemorrhage.
Conclusion: SPH was associated with the patency of the splenic vein and the formation of distinctive perigastric collateral veins. Surgery and/or endoscopic treatment were recommended, particularly for patients who have experienced a significant amount of gastrointestinal bleeding and have failed conservative treatment. 
کلیدواژه‌ها
Pancreatic diseases؛ Sinistral portal hypertension؛ Varicose veins
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مراجع
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