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An Infrared Non-Invasive System for Measuring Blood Glucose: A Primary Study using Serum Samples | ||
| Journal of Biomedical Physics and Engineering | ||
| مقالات آماده انتشار، اصلاح شده برای چاپ، انتشار آنلاین از تاریخ 26 فروردین 1403 اصل مقاله (1.13 M) | ||
| نوع مقاله: Original Research | ||
| نویسندگان | ||
| Ramin Jokari1؛ Zahra Mahyari2؛ Mohammad Javad Moulodi2، 3؛ Seyyed Mohammad Fatemi Ghiri2؛ Hadi Tajalizadeh2، 3؛ Ali Loloee Jahromi2؛ Alireza Nakhostin2؛ Gholamreza Abdollahifard4؛ Hossein Parsaei* 5، 6 | ||
| 1Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran | ||
| 2Basamad Azma Novin Pars Co. Ltd, Innovation and Acceleration Center, Shiraz University of Medical Sciences, Shiraz, Iran | ||
| 3Substance Abuse and Mental Health Research Center, Shiraz University of Medical Sciences, Shiraz, Iran | ||
| 4Department of Community Medicine, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran | ||
| 5Department of Medical Physics and Engineering, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran | ||
| 6Shiraz Neuroscience Research Center, Shiraz University of Medical Sciences, Shiraz, Iran | ||
| چکیده | ||
| Background: Diabetes is a global concern, with an estimated 2 million individuals expected to be affected by the condition by 2024. Non-invasive glucose monitoring devices can greatly enhance patient care and management. Objective: This study aimed to develop an instrument capable of non-invasively measuring blood glucose levels using an infrared transmitter and receiver, with data processing performed by a dedicated processor. Material and Methods: This analytical study develops a glucometer that incorporates a power supply, a light source, a light detector, a sampler, and signal processing components to enable non-invasive glucose measurements. The instrument was calibrated using sugar solution samples with known glucose concentrations. It was then tested using serum samples from diabetic patients with accuracy, which was evaluated using Clarke’s grid analysis. Results: Testing of the designed glucometer revealed that 83% of the serum samples fell within zone A of Clarke’s grid analysis, indicating high accuracy. The remaining 17% of samples were classified in zone B, with no samples falling in zones C, D, or E. Conclusion: The developed glucometer demonstrated higher accuracy in measuring glucose concentrations above 200 mg/dl. Despite the use of serum samples in this experiment, 83% of the results were located in zone A leads to the capability of non-invasively measuring blood glucose levels. Further studies are required to validate the device’s accuracy in a larger population and assess its utility in clinical practice. | ||
| کلیدواژه‌ها | ||
| Blood Glucose؛ Blood Glucose Self-Monitoring؛ Continuous Glucose Monitoring؛ Diabetes؛ Glucometer؛ Non-Invasive Blood Glucose Measurement | ||
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آمار تعداد مشاهده مقاله: 4,954 تعداد دریافت فایل اصل مقاله: 11 |
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