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Qujeq, Durdi, Abbasi Natajomrani, Roya, Hajihosseini, Reza, Hosseini, Vahid, Kazemi Veisari, Arash, Hoznian, Khadijeh. (1403). The Clinical Utility of Biochemical Biomarkers in Colorectal Cancer. سامانه مدیریت نشریات علمی, 15(4), 272-280. doi: 10.30476/mejc.2024.98579.1910
Durdi Qujeq; Roya Abbasi Natajomrani; Reza Hajihosseini; Vahid Hosseini; Arash Kazemi Veisari; Khadijeh Hoznian. "The Clinical Utility of Biochemical Biomarkers in Colorectal Cancer". سامانه مدیریت نشریات علمی, 15, 4, 1403, 272-280. doi: 10.30476/mejc.2024.98579.1910
Qujeq, Durdi, Abbasi Natajomrani, Roya, Hajihosseini, Reza, Hosseini, Vahid, Kazemi Veisari, Arash, Hoznian, Khadijeh. (1403). 'The Clinical Utility of Biochemical Biomarkers in Colorectal Cancer', سامانه مدیریت نشریات علمی, 15(4), pp. 272-280. doi: 10.30476/mejc.2024.98579.1910
Qujeq, Durdi, Abbasi Natajomrani, Roya, Hajihosseini, Reza, Hosseini, Vahid, Kazemi Veisari, Arash, Hoznian, Khadijeh. The Clinical Utility of Biochemical Biomarkers in Colorectal Cancer. سامانه مدیریت نشریات علمی, 1403; 15(4): 272-280. doi: 10.30476/mejc.2024.98579.1910

The Clinical Utility of Biochemical Biomarkers in Colorectal Cancer

Middle East Journal of Cancer
مقاله 2، دوره 15، شماره 4 - شماره پیاپی 60، دی 2024، صفحه 272-280    اصل مقاله (841.84 K)
نوع مقاله: Review Article(s)
شناسه دیجیتال (DOI): 10.30476/mejc.2024.98579.1910
نویسندگان
Durdi Qujeq1؛ Roya Abbasi Natajomrani* 2؛ Reza Hajihosseini3؛ Vahid Hosseini4؛ Arash Kazemi Veisari4؛ Khadijeh Hoznian5
1Department of Clinical Biochemistry, Faculty of Medicine, Babol University of Medical Sciences, Babol, Iran
2Department of Food and Drug Deputy, Mazandaran University of Medical Sciences, Sari, Iran
3Department of Biochemistry, Payame Noor University, Tehran, Iran
4Non-communicable Diseases Institute, Gut and Liver Research Center, Mazandaran University of Medical Sciences, Sari, Iran
5Imam Khomeini Educational Hospital, Mazandaran University of Medical Sciences, Sari, Iran
چکیده
Colorectal cancer (CRC) ranks as the third most prevalent cancer worldwide and is a leading cause of cancer-related mortality. Since many colon cancers present no significant clinical symptoms, identifying new biomarkers or a set of biological indicators significant for clinical trials is crucial for the early detection of CRC. This advancement also aids in establishing new objectives for interventional therapeutic strategies against the disease. Currently, research is exploring various proteins, glycoproteins, and cellular and humoral substances involved in cellular homeostasis mechanisms as potential cancer markers. This review examines the potential utility of fucosylation and sialylation processes, as well as sex hormones, as biomarkers in the diagnosis and prognosis of CRC. A comprehensive search was conducted in PUBMED, MEDLINE, and Google Scholar, supplemented by a manual search of relevant journals. The keywords were L-fucose, sialic acid, fucosyltransferase-4, galectin-3, and steroid hormones in CRCs.

تازه های تحقیق

Durdi Qujeq (Google Scholar)

Roya Abbasi Natajomrani (Google Scholar)

کلیدواژه‌ها
Glycoproteins؛ Fucosyltransferase؛ Galectin؛ L-fucose؛ Sialic acid
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