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Zeinalpour, Adel, Taleghani, Mostafa, Rostami, Tayebe, Ebrahimibagha, Hamed. (1402). Factors Affecting 5-Year Mortality of Colon Cancer in a Single Center. سامانه مدیریت نشریات علمی, 11(4), 134-138. doi: 10.30476/acrr.2024.99969.1187
Adel Zeinalpour; Mostafa Taleghani; Tayebe Rostami; Hamed Ebrahimibagha. "Factors Affecting 5-Year Mortality of Colon Cancer in a Single Center". سامانه مدیریت نشریات علمی, 11, 4, 1402, 134-138. doi: 10.30476/acrr.2024.99969.1187
Zeinalpour, Adel, Taleghani, Mostafa, Rostami, Tayebe, Ebrahimibagha, Hamed. (1402). 'Factors Affecting 5-Year Mortality of Colon Cancer in a Single Center', سامانه مدیریت نشریات علمی, 11(4), pp. 134-138. doi: 10.30476/acrr.2024.99969.1187
Zeinalpour, Adel, Taleghani, Mostafa, Rostami, Tayebe, Ebrahimibagha, Hamed. Factors Affecting 5-Year Mortality of Colon Cancer in a Single Center. سامانه مدیریت نشریات علمی, 1402; 11(4): 134-138. doi: 10.30476/acrr.2024.99969.1187

Factors Affecting 5-Year Mortality of Colon Cancer in a Single Center

Iranian Journal of Colorectal Research
مقاله 4، دوره 11، شماره 4، اسفند 2023، صفحه 134-138    اصل مقاله (610.11 K)
نوع مقاله: Research/Original Article
شناسه دیجیتال (DOI): 10.30476/acrr.2024.99969.1187
نویسندگان
Adel Zeinalpour1؛ Mostafa Taleghani2؛ Tayebe Rostami3؛ Hamed Ebrahimibagha* 2
1Department of General Surgery, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
2Shahid Beheshti University of Medical Sciences, Tehran, Iran
3Department of Pathology, Shahid Beheshti University of Medical sciences, Tehran, Iran
چکیده
Introduction: Colon cancer is considered one of the most lethal cancers globally, and various factors are thought to be associated with the survival rate of this disease. Identifying these factors is helpful in better management, efficient treatment, and increased patient survival. Therefore, this study aimed to investigate the relationship between demographic, clinical, and laboratory findings of colon cancer patients and their 5-year mortality rates.
Methods: A retrospective study was conducted on 54 patients diagnosed with colon cancer, and their demographic data, comorbidities, clinical and laboratory data were collected. The Spearman non-parametric statistical correlation test was utilized to analyze the relationships between these variables and the 5-year mortality of colon cancer. A P-value<0.05 was considered statistically significant. 
Results: The mean age of the patients was 60±12 years. A significant relationship was detected between carcinoembryonic antigen (CEA) level, recent significant weight loss, and pathological stage with the 5-year mortality of colon cancer. However, no statistically significant relationship was found between the 5-year mortality of colon cancer and comorbidities, age, gender, anatomical location of cancer, number of postoperative chemotherapy sessions, type of surgery, degree of tumor differentiation, lymphocyte count, serum albumin level, hemoglobin level, or need for emergency surgery.
Conclusion: CEA level, significant weight loss, and pathological stage of tumors may affect the 5-year mortality of colon cancer. 
کلیدواژه‌ها
Colon Cancer؛ Mortality؛ Survival Rate
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