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The Prevalence of Metabolic Syndrome in Patients with Non-Alcoholic Fatty Liver Disease in Ahvaz, Iran | ||
| International Journal of Nutrition Sciences | ||
| مقاله 2، دوره 8، شماره 4، اسفند 2023، صفحه 207-215 اصل مقاله (1015.57 K) | ||
| نوع مقاله: Original Article | ||
| شناسه دیجیتال (DOI): 10.30476/ijns.2023.99502.1245 | ||
| نویسندگان | ||
| Alireza Jahanshahi* ؛ Homeira Rashidi؛ Arian Ezzatpanah؛ Saeed Hessam؛ Eskandar Hajiani؛ Fatemeh Amiri | ||
| Diabetes Research Center, Health Research Institute, Ahvaz Jundishapur University of medical sciences, Ahvaz, Iran | ||
| چکیده | ||
| Background: Previous studies have shown that there may be a link between metabolic syndrome (MetS) and non-alcoholic fatty liver disease (NAFLD). Therefore, the present study was designed with the aim of investigating the prevalence of metabolic syndrome in patients with NAFLD. Methods: One hundred and fourteen patients with NAFLD were recruited to the study in Ahvaz, Iran. The Metabolic Syndrome Severity Score (MSSS) was used in an online calculator from available information. The NAFLD determined based on clinical or laboratory symptoms, and liver ultrasonography. The determination of its severity was made using liver elastography. Univariate and multivariate analyses were used to correlate the collected parameters. Receiver operating characteristic (ROC) curve was used to evaluate the cutoff value of fibrograde and steagrade that predicts fibrosis and steatosis. Results: Totally, 69 patients (60.5%) had MetS. The chance of higher grade of steatosis in patients with MetS was 3.76 times higher than that of patients without MetS (p=0.003). Moreover, the correlation coefficient between MSSS and osteoscore was 0.274 (p=0.023). MSSS had the predictive power to detect steagrade (0:1, 2, 3) with 83.78% sensitivity and 59.38% specificity (p=0.005) and a cutoff point of 0.45. Conclusion: MSSS was shown to have the predictive power to detect steatosis grades. However, further studies are required to determine whether fibrosis has a relationship with severity of MetS. | ||
تازه های تحقیق | ||
Alireza Jahanshahi (Google Scholar) | ||
| کلیدواژه‌ها | ||
| Non-alcoholic fatty liver disease؛ Metabolic syndrome؛ Liver steatosis؛ Iran | ||
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