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Ebadati, Sahar, Sahebari, Maryam, Ahmadzadeh, Amir Mahmoud, Emadzadeh, Maryam, Khoroushi, Farzaneh, Ragati Haghi, Hedieh, Giti, Ramesh, Aminzadeh, Behzad. (1402). Correlation of US-7 and US-9 Scores with Disease Activity Score using 28 Joint Counts (DAS28) in Patients with Rheumatoid Arthritis. سامانه مدیریت نشریات علمی, 49(3), 167-175. doi: 10.30476/ijms.2023.97776.2996
Sahar Ebadati; Maryam Sahebari; Amir Mahmoud Ahmadzadeh; Maryam Emadzadeh; Farzaneh Khoroushi; Hedieh Ragati Haghi; Ramesh Giti; Behzad Aminzadeh. "Correlation of US-7 and US-9 Scores with Disease Activity Score using 28 Joint Counts (DAS28) in Patients with Rheumatoid Arthritis". سامانه مدیریت نشریات علمی, 49, 3, 1402, 167-175. doi: 10.30476/ijms.2023.97776.2996
Ebadati, Sahar, Sahebari, Maryam, Ahmadzadeh, Amir Mahmoud, Emadzadeh, Maryam, Khoroushi, Farzaneh, Ragati Haghi, Hedieh, Giti, Ramesh, Aminzadeh, Behzad. (1402). 'Correlation of US-7 and US-9 Scores with Disease Activity Score using 28 Joint Counts (DAS28) in Patients with Rheumatoid Arthritis', سامانه مدیریت نشریات علمی, 49(3), pp. 167-175. doi: 10.30476/ijms.2023.97776.2996
Ebadati, Sahar, Sahebari, Maryam, Ahmadzadeh, Amir Mahmoud, Emadzadeh, Maryam, Khoroushi, Farzaneh, Ragati Haghi, Hedieh, Giti, Ramesh, Aminzadeh, Behzad. Correlation of US-7 and US-9 Scores with Disease Activity Score using 28 Joint Counts (DAS28) in Patients with Rheumatoid Arthritis. سامانه مدیریت نشریات علمی, 1402; 49(3): 167-175. doi: 10.30476/ijms.2023.97776.2996

Correlation of US-7 and US-9 Scores with Disease Activity Score using 28 Joint Counts (DAS28) in Patients with Rheumatoid Arthritis

Iranian Journal of Medical Sciences
مقاله 4، دوره 49، شماره 3، خرداد 2024، صفحه 167-175    اصل مقاله (1.56 M)
نوع مقاله: Original Article(s)
شناسه دیجیتال (DOI): 10.30476/ijms.2023.97776.2996
نویسندگان
Sahar Ebadati1؛ Maryam Sahebari2؛ Amir Mahmoud Ahmadzadeh3، 4؛ Maryam Emadzadeh5؛ Farzaneh Khoroushi4؛ Hedieh Ragati Haghi6؛ Ramesh Giti1؛ Behzad Aminzadeh* 4
1Department of Radiology, Medical Imaging Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
2Rheumatic Diseases Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
3Transplant Research Center, Clinical Research Institute, Mashhad University of Medical Sciences, Mashhad, Iran
4Department of Radiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
5Clinical Research Development Unit, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran
6Department of Radiology, Brigham and Women’s Hospital, Boston, MA 02215, USA
چکیده
Background: The attentive management of rheumatoid arthritis (RA) has attracted particular attention. The German 7-joint Ultrasound (US-7) is the first scoring system that combines bone erosions and soft tissue lesions in a single composite scoring system. This study aimed to assess the correlation between US-7 and Disease Activity Score Using 28 Joint Counts (DAS28) in clinically active RA patients. The efficacy of a novel ultrasound score-based system, the US-9 score (joints assessed with US-7 plus knees), was also compared with the standard US-7 score.
Methods: All the RA patients referred to the outpatient rheumatology clinic of Ghaem Hospital, Mashhad, Iran, during 2019-2020 were included. 28 joints were clinically examined to calculate DAS28. Nine joints were assessed comprising the German US-7 plus knees using grayscale ultrasonography (GSUS) and power Doppler ultrasonography (PDUS). Retrieved data were analyzed by SPSS software, version 22. The Spearman Correlation test was used to find the correlation between DAS28 and ultrasonographic findings. The statistical significance level was set at P<0.05. 
Results: This study was composed of thirty-five RA patients with a mean age of 49.1±12.0 years. US-7 synovitis scores in GSUS and PDUS were significantly correlated with DAS28 (P=0.02, r=0.38 and P=0.003, r=0.48, respectively). US-9 synovitis scores in GSUS and PDUS were also significantly correlated with DAS28 (P=0.003, r=0.49 and P=0.006, r=0.45, respectively). The synovitis score measured by GSUS was significantly correlated with the GSUS knee synovial score (P=0.01, r=0.42).
Conclusion: Ultrasound assessment of large joints such as knees can be an effective approach to determining RA severity. However, it can be proposed that adding more involved joints into the sonographic assessment does not necessarily provide a better clinical correlation.
کلیدواژه‌ها
Arthritis, rheumatoid؛ Ultrasonography؛ Joints؛ Ultrasonography, doppler
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