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Shamsdin, Seyedeh Azra, Akrami, Hassan, Nikmanesh, yousef, samani, hasti, Fattahi, mohammadjavad. (1402). Investigation of Serum PIVKA-II Levels in Patients with Helicobacter pylori Infection and Normal Group. سامانه مدیریت نشریات علمی, 11(2), -. doi: 10.30476/acrr.2023.99923.1184
Seyedeh Azra Shamsdin; Hassan Akrami; yousef Nikmanesh; hasti samani; mohammadjavad Fattahi. "Investigation of Serum PIVKA-II Levels in Patients with Helicobacter pylori Infection and Normal Group". سامانه مدیریت نشریات علمی, 11, 2, 1402, -. doi: 10.30476/acrr.2023.99923.1184
Shamsdin, Seyedeh Azra, Akrami, Hassan, Nikmanesh, yousef, samani, hasti, Fattahi, mohammadjavad. (1402). 'Investigation of Serum PIVKA-II Levels in Patients with Helicobacter pylori Infection and Normal Group', سامانه مدیریت نشریات علمی, 11(2), pp. -. doi: 10.30476/acrr.2023.99923.1184
Shamsdin, Seyedeh Azra, Akrami, Hassan, Nikmanesh, yousef, samani, hasti, Fattahi, mohammadjavad. Investigation of Serum PIVKA-II Levels in Patients with Helicobacter pylori Infection and Normal Group. سامانه مدیریت نشریات علمی, 1402; 11(2): -. doi: 10.30476/acrr.2023.99923.1184

Investigation of Serum PIVKA-II Levels in Patients with Helicobacter pylori Infection and Normal Group

Iranian Journal of Colorectal Research
دوره 11، شماره 2، شهریور 2023    اصل مقاله (721.79 K)
نوع مقاله: Research/Original Article
شناسه دیجیتال (DOI): 10.30476/acrr.2023.99923.1184
نویسندگان
Seyedeh Azra Shamsdin* 1؛ Hassan Akrami2؛ yousef Nikmanesh3؛ hasti samani4؛ mohammadjavad Fattahi* 5
1Gasteroenterohepatology Research Center Shiraz University of Medical Sciences Shiraz, Iran
2Gastroenterohepatology Research Center, Shiraz University of Medical Sciences, Shiraz, IranShiraz
3Gastroenterohepatology Research Center, Shiraz University of Medical Sciences, Fars, Shiraz, Iran
4Gastroenterohepatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
5Institute for Cancer Research, Shiraz University of Medical Science, Shiraz, Iran
چکیده
Abstract
Background: Helicobacter pylori is one of the most common microorganisms known in humans, and as a risk factor it can result in gastric cancer, therefore we decided to evaluate the serum level of PIVKA-II in patients with Helicobacter pylori (H. pylori) infection and normal group.
Materials and Methods: This study was performed on 90 patients (45 patients with H. pylori infection and 45 patients in the control group). After recording demographic information, serum level of PIVKA-II was measured in two groups by ELISA method.
Results: The findings of our study showed no significant difference between the serum level of PIVKA-II in patients with H. pylori compared to those without infection (p = 0.08) but at the age of less than 40 years, the mean serum level of PIVKA-II in patients with H. pylori was significantly lower than the control group (p = 0.026), Also in men infected by H. pylori the mean serum level of PIVKA-II was significantly less than the control group. (p = 0.04)
Conclusion: The results of the present study indicate that the serum level of PIVKA-II in infected men as well as in people under 40 years of age with H. pylori infection, was significantly lower than the control group. Also, serum PIVKA-II levels in patients were significantly lower in men than women and in those under 40 years of age compared with those over 40 years of age.
کلیدواژه‌ها
Helicobacter pylori؛ PIVKA-II؛ Gastritis؛ Infection
مراجع
 

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