تعداد نشریات | 20 |
تعداد شمارهها | 1,053 |
تعداد مقالات | 9,691 |
تعداد مشاهده مقاله | 12,896,280 |
تعداد دریافت فایل اصل مقاله | 6,144,851 |
Investigation of Serum PIVKA-II Levels in Patients with Helicobacter pylori Infection and Normal Group | ||
Iranian Journal of Colorectal Research | ||
دوره 11، شماره 2، شهریور 2023 اصل مقاله (721.79 K) | ||
نوع مقاله: Research/Original Article | ||
شناسه دیجیتال (DOI): 10.30476/acrr.2023.99923.1184 | ||
نویسندگان | ||
Seyedeh Azra Shamsdin* 1؛ Hassan Akrami2؛ yousef Nikmanesh3؛ hasti samani4؛ mohammadjavad Fattahi* 5 | ||
1Gasteroenterohepatology Research Center Shiraz University of Medical Sciences Shiraz, Iran | ||
2Gastroenterohepatology Research Center, Shiraz University of Medical Sciences, Shiraz, IranShiraz | ||
3Gastroenterohepatology Research Center, Shiraz University of Medical Sciences, Fars, Shiraz, Iran | ||
4Gastroenterohepatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran | ||
5Institute for Cancer Research, Shiraz University of Medical Science, Shiraz, Iran | ||
چکیده | ||
Abstract Background: Helicobacter pylori is one of the most common microorganisms known in humans, and as a risk factor it can result in gastric cancer, therefore we decided to evaluate the serum level of PIVKA-II in patients with Helicobacter pylori (H. pylori) infection and normal group. Materials and Methods: This study was performed on 90 patients (45 patients with H. pylori infection and 45 patients in the control group). After recording demographic information, serum level of PIVKA-II was measured in two groups by ELISA method. Results: The findings of our study showed no significant difference between the serum level of PIVKA-II in patients with H. pylori compared to those without infection (p = 0.08) but at the age of less than 40 years, the mean serum level of PIVKA-II in patients with H. pylori was significantly lower than the control group (p = 0.026), Also in men infected by H. pylori the mean serum level of PIVKA-II was significantly less than the control group. (p = 0.04) Conclusion: The results of the present study indicate that the serum level of PIVKA-II in infected men as well as in people under 40 years of age with H. pylori infection, was significantly lower than the control group. Also, serum PIVKA-II levels in patients were significantly lower in men than women and in those under 40 years of age compared with those over 40 years of age. | ||
کلیدواژهها | ||
Helicobacter pylori؛ PIVKA-II؛ Gastritis؛ Infection | ||
مراجع | ||
| ||
آمار تعداد مشاهده مقاله: 39 تعداد دریافت فایل اصل مقاله: 64 |