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Abtahian, Ameneh, Rezaei, Behzad, Moradpour, Gholamreza, Aghakhani, Ladan, Aghapoor, Avkan, Banihashemi, Seyed Hesamaddin, Izadi, Saeideh, Mohammadi, Zahra, Haghighat, Neda. (1402). The Effect of Bariatric Surgery on Polycystic Ovary Syndrome (PCOS) Symptoms and Related Hormones Improvement in Women with Morbid Obesity. سامانه مدیریت نشریات علمی, 8(3), 144-149. doi: 10.30476/ijns.2023.99503.1246
Ameneh Abtahian; Behzad Rezaei; Gholamreza Moradpour; Ladan Aghakhani; Avkan Aghapoor; Seyed Hesamaddin Banihashemi; Saeideh Izadi; Zahra Mohammadi; Neda Haghighat. "The Effect of Bariatric Surgery on Polycystic Ovary Syndrome (PCOS) Symptoms and Related Hormones Improvement in Women with Morbid Obesity". سامانه مدیریت نشریات علمی, 8, 3, 1402, 144-149. doi: 10.30476/ijns.2023.99503.1246
Abtahian, Ameneh, Rezaei, Behzad, Moradpour, Gholamreza, Aghakhani, Ladan, Aghapoor, Avkan, Banihashemi, Seyed Hesamaddin, Izadi, Saeideh, Mohammadi, Zahra, Haghighat, Neda. (1402). 'The Effect of Bariatric Surgery on Polycystic Ovary Syndrome (PCOS) Symptoms and Related Hormones Improvement in Women with Morbid Obesity', سامانه مدیریت نشریات علمی, 8(3), pp. 144-149. doi: 10.30476/ijns.2023.99503.1246
Abtahian, Ameneh, Rezaei, Behzad, Moradpour, Gholamreza, Aghakhani, Ladan, Aghapoor, Avkan, Banihashemi, Seyed Hesamaddin, Izadi, Saeideh, Mohammadi, Zahra, Haghighat, Neda. The Effect of Bariatric Surgery on Polycystic Ovary Syndrome (PCOS) Symptoms and Related Hormones Improvement in Women with Morbid Obesity. سامانه مدیریت نشریات علمی, 1402; 8(3): 144-149. doi: 10.30476/ijns.2023.99503.1246

The Effect of Bariatric Surgery on Polycystic Ovary Syndrome (PCOS) Symptoms and Related Hormones Improvement in Women with Morbid Obesity

International Journal of Nutrition Sciences
مقاله 2، دوره 8، شماره 3، آذر 2023، صفحه 144-149    اصل مقاله (379.74 K)
نوع مقاله: Original Article
شناسه دیجیتال (DOI): 10.30476/ijns.2023.99503.1246
نویسندگان
Ameneh Abtahian1؛ Behzad Rezaei2؛ Gholamreza Moradpour2؛ Ladan Aghakhani2؛ Avkan Aghapoor3؛ Seyed Hesamaddin Banihashemi4؛ Saeideh Izadi2؛ Zahra Mohammadi2؛ Neda Haghighat* 5
1Department of Obstetrics and Gynecology, School of Medicine, Shahid Beheshti University Of Medical Sciences, Tehran, Iran
2Laparascopy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
3Iranian Hospital Dubai, Iranian Red Crescent Society, Dubai, United Arab Emirates
4Department of surgery, School of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran
5Laparoscopy Research Center, Shiraz University of medical sciences, Shiraz, Iran
چکیده
Background: Obesity is associated with developing polycystic ovary syndrome (PCOS). The present study investigated whether weight loss after bariatric surgery could improve symptoms and related hormones in women with morbid obesity.
Methods: In a retrospective observational study, 50 women aged 18-40 years with body mass index (BMI)=42.3 kg/m2 who underwent laparoscopic Roux-en-Y gastric bypass (RYGB) were enrolled. Evaluation of anthropometric data, serum testosterone, luteinizing hormone (LH), follicle-stimulating hormone (FSH), prolactin (PRL), fasting plasma
glucose (FPG), and lipid profile were measured preoperatively and at 1-year follow-up
Results: Of 50 women, 32 (64%) women were diagnosed to have PCOS. The mean BMI at 1-year follow-up was 27.05 kg/m2. Hirsutism and irregular menstruation resolved entirely among 68.8% (11/16) and 100% (18/18) at 1-year follow-up. There was a significant decrease in total serum testosterone (2.1±0.2 to 0.9±0.1 ng/mL) and LH (8.5±3.36 to 5.02±2.4 mIU/mL) at 1-year follow-up, whether changes in levels of serum FSH, PRL were not significant.
Conclusion: Bariatric surgery was effective in weight loss and improvement of PCOS symptoms and related hormones in women with morbid obesity. Thus, women with PCOS and morbid obesity should be eligible for bariatric surgery.

تازه های تحقیق

Neda Haghighat (Google Scholar)

کلیدواژه‌ها
Polycystic ovary syndrome؛ Obesity؛ Bariatric surgery؛ Weight loss؛ Iran
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