|تعداد مشاهده مقاله||12,794,568|
|تعداد دریافت فایل اصل مقاله||6,126,748|
Evaluation of the Effect of Benzydamine Hydrochloride on the Intensity of Gag Reflex: A Randomized Single-Blind Clinical Trial
|Journal of Dentistry|
|مقالات آماده انتشار، پذیرفته شده، انتشار آنلاین از تاریخ 06 شهریور 1402 اصل مقاله (398.95 K)|
|نوع مقاله: Original Article|
|شناسه دیجیتال (DOI): 10.30476/dentjods.2023.97675.2032|
|Mohammad Mehdi Torabi1؛ Reyhaneh Shoorgashti2؛ Farnaz Hajifattahi3؛ Simin Lesan* 4|
|1Dentist. Tehran, Iran|
|2Dentist, Tehran, Iran.|
|3Assistant Professor, Oral Medicine Department, Islamic Azad University of Medical Sciences, Dental branch, Tehran, Iran.|
|4Assistant Professor, Oral Medicine Department, Islamic Azad University of Medical Sciences, Dental branch, Tehran, Iran|
|Statement of the Problem: Gag reflex is among the most common problems during dental and endoscopic procedures. Benzydamine hydrochloride is a non-steroidal anti-inflammatory medica-tion and a local anesthetic that might be useful in reducing the gag reflex. |
Purpose: This study aimed to evaluate the effects of benzydamine hydrochloride mouthwash on the intensity of the gag reflex.
Materials and Method: In this randomized clinical trial study, 30 participants aged 21-26 with a gag trigger point index (GTPI) higher than 2 were divided into 2 groups. In the case group, 15 ml of 0.15% benzydamine hydrochloride mouthwash was gargled for 1 minute, and after 10 minutes GTPI test was conducted. In the control group, 4 puffs of 10% lidocaine spray were applied to the mucosa of the targeted area, and after 5 minutes, GTPI was measured. Participants were asked about the taste and smell of the medications.
Results: GTPI was significantly reduced in both groups. In the lidocaine group, the GTPI score changed from 4.47 to 2.00 (P<0.001), and that for the benzydamine group was 4.20 to 1.47 (P<0.001). The variance rate of the gag reflex was -2.73 and -2.47 in the benzydamine group and lidocaine group, respectively. However, this reduction was not statistically significant between the two groups. Also, benzydamine mouthwash has a significantly better taste and smell than lido-caine (P= 0.001).
Conclusion: The results of this study showed that benzydamine mouthwash could be used quite effectively in reducing the gag reflex.
|Reflex؛ Gagging؛ Benzydamine؛ Local anesthetic؛ lidocaine|
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