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Evaluation of the Effect of Benzydamine Hydrochloride on the Intensity of Gag Reflex: A Randomized Single-Blind Clinical Trial | ||
Journal of Dentistry | ||
مقالات آماده انتشار، پذیرفته شده، انتشار آنلاین از تاریخ 06 شهریور 1402 اصل مقاله (398.95 K) | ||
نوع مقاله: Original Article | ||
شناسه دیجیتال (DOI): 10.30476/dentjods.2023.97675.2032 | ||
نویسندگان | ||
Mohammad Mehdi Torabi1؛ Reyhaneh Shoorgashti2؛ Farnaz Hajifattahi3؛ Simin Lesan* 4 | ||
1Dentist. Tehran, Iran | ||
2Dentist, Tehran, Iran. | ||
3Assistant Professor, Oral Medicine Department, Islamic Azad University of Medical Sciences, Dental branch, Tehran, Iran. | ||
4Assistant Professor, Oral Medicine Department, Islamic Azad University of Medical Sciences, Dental branch, Tehran, Iran | ||
چکیده | ||
Statement of the Problem: Gag reflex is among the most common problems during dental and endoscopic procedures. Benzydamine hydrochloride is a non-steroidal anti-inflammatory medica-tion and a local anesthetic that might be useful in reducing the gag reflex. Purpose: This study aimed to evaluate the effects of benzydamine hydrochloride mouthwash on the intensity of the gag reflex. Materials and Method: In this randomized clinical trial study, 30 participants aged 21-26 with a gag trigger point index (GTPI) higher than 2 were divided into 2 groups. In the case group, 15 ml of 0.15% benzydamine hydrochloride mouthwash was gargled for 1 minute, and after 10 minutes GTPI test was conducted. In the control group, 4 puffs of 10% lidocaine spray were applied to the mucosa of the targeted area, and after 5 minutes, GTPI was measured. Participants were asked about the taste and smell of the medications. Results: GTPI was significantly reduced in both groups. In the lidocaine group, the GTPI score changed from 4.47 to 2.00 (P<0.001), and that for the benzydamine group was 4.20 to 1.47 (P<0.001). The variance rate of the gag reflex was -2.73 and -2.47 in the benzydamine group and lidocaine group, respectively. However, this reduction was not statistically significant between the two groups. Also, benzydamine mouthwash has a significantly better taste and smell than lido-caine (P= 0.001). Conclusion: The results of this study showed that benzydamine mouthwash could be used quite effectively in reducing the gag reflex. | ||
کلیدواژهها | ||
Reflex؛ Gagging؛ Benzydamine؛ Local anesthetic؛ lidocaine | ||
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