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Torabi, Mohammad Mehdi, Shoorgashti, Reyhaneh, Haji Fattahi, Farnaz, Lesan, Simin. (1403). Evaluation of the Effect of Benzydamine Hydrochloride on the Intensity of Gag Reflex: A Randomized Single-Blind Clinical Trial. سامانه مدیریت نشریات علمی, 25(2), 162-168. doi: 10.30476/dentjods.2023.97675.2032
Mohammad Mehdi Torabi; Reyhaneh Shoorgashti; Farnaz Haji Fattahi; Simin Lesan. "Evaluation of the Effect of Benzydamine Hydrochloride on the Intensity of Gag Reflex: A Randomized Single-Blind Clinical Trial". سامانه مدیریت نشریات علمی, 25, 2, 1403, 162-168. doi: 10.30476/dentjods.2023.97675.2032
Torabi, Mohammad Mehdi, Shoorgashti, Reyhaneh, Haji Fattahi, Farnaz, Lesan, Simin. (1403). 'Evaluation of the Effect of Benzydamine Hydrochloride on the Intensity of Gag Reflex: A Randomized Single-Blind Clinical Trial', سامانه مدیریت نشریات علمی, 25(2), pp. 162-168. doi: 10.30476/dentjods.2023.97675.2032
Torabi, Mohammad Mehdi, Shoorgashti, Reyhaneh, Haji Fattahi, Farnaz, Lesan, Simin. Evaluation of the Effect of Benzydamine Hydrochloride on the Intensity of Gag Reflex: A Randomized Single-Blind Clinical Trial. سامانه مدیریت نشریات علمی, 1403; 25(2): 162-168. doi: 10.30476/dentjods.2023.97675.2032

Evaluation of the Effect of Benzydamine Hydrochloride on the Intensity of Gag Reflex: A Randomized Single-Blind Clinical Trial

Journal of Dentistry
مقاله 14، دوره 25، شماره 2 - شماره پیاپی 83، شهریور 2024، صفحه 162-168    اصل مقاله (308.99 K)
نوع مقاله: Original Article
شناسه دیجیتال (DOI): 10.30476/dentjods.2023.97675.2032
نویسندگان
Mohammad Mehdi Torabi1؛ Reyhaneh Shoorgashti2؛ Farnaz Haji Fattahi3؛ Simin Lesan* 3
1Dentist. Tehran, Iran
2Dentist, Tehran, Iran.
3Dept. of Oral Medicine, Islamic Azad University of Medical Sciences, Dental Branch, Tehran, Iran.
چکیده
Statement of the Problem: Gag reflex is among the most common problems during dental and endoscopic procedures. Benzydamine hydrochloride is a non-steroidal anti-inflammatory medica-tion and a local anesthetic that might be useful in reducing the gag reflex.

Purpose: This study aimed to evaluate the effects of benzydamine hydrochloride mouthwash on the intensity of the gag reflex.

Materials and Method: In this randomized clinical trial study, 30 participants aged 21-26 with a gag trigger point index (GTPI) higher than 2 were divided into 2 groups. In the case group, 15 ml of 0.15% benzydamine hydrochloride mouthwash was gargled for 1 minute, and after 10 minutes GTPI test was conducted. In the control group, 4 puffs of 10% lidocaine spray were applied to the mucosa of the targeted area, and after 5 minutes, GTPI was measured. Participants were asked about the taste and smell of the medications.

Results: GTPI was significantly reduced in both groups. In the lidocaine group, the GTPI score changed from 4.47 to 2.00 (P<0.001), and that for the benzydamine group was 4.20 to 1.47 (P<0.001). The variance rate of the gag reflex was -2.73 and -2.47 in the benzydamine group and lidocaine group, respectively. However, this reduction was not statistically significant between the two groups. Also, benzydamine mouthwash has a significantly better taste and smell than lido-caine (P= 0.001).

Conclusion: The results of this study showed that benzydamine mouthwash could be used quite effectively in reducing the gag reflex.
کلیدواژه‌ها
Reflex؛ Gagging؛ Benzydamine؛ Local anesthetic؛ lidocaine
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