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Igder, Somayeh, Zamani, Mozhdeh, Vakili, Omid, Siri, Morvarid, Rashidi, Mojtaba, Hosseini, Seyed Vahid, Mokarram, Pooneh. (1401). Where do liver injuries stand in the post-COVID-19 era? A review of the connection between long COVID and liver diseases. سامانه مدیریت نشریات علمی, 11(1), 1-14. doi: 10.30476/acrr.2023.98911.1179
Somayeh Igder; Mozhdeh Zamani; Omid Vakili; Morvarid Siri; Mojtaba Rashidi; Seyed Vahid Hosseini; Pooneh Mokarram. "Where do liver injuries stand in the post-COVID-19 era? A review of the connection between long COVID and liver diseases". سامانه مدیریت نشریات علمی, 11, 1, 1401, 1-14. doi: 10.30476/acrr.2023.98911.1179
Igder, Somayeh, Zamani, Mozhdeh, Vakili, Omid, Siri, Morvarid, Rashidi, Mojtaba, Hosseini, Seyed Vahid, Mokarram, Pooneh. (1401). 'Where do liver injuries stand in the post-COVID-19 era? A review of the connection between long COVID and liver diseases', سامانه مدیریت نشریات علمی, 11(1), pp. 1-14. doi: 10.30476/acrr.2023.98911.1179
Igder, Somayeh, Zamani, Mozhdeh, Vakili, Omid, Siri, Morvarid, Rashidi, Mojtaba, Hosseini, Seyed Vahid, Mokarram, Pooneh. Where do liver injuries stand in the post-COVID-19 era? A review of the connection between long COVID and liver diseases. سامانه مدیریت نشریات علمی, 1401; 11(1): 1-14. doi: 10.30476/acrr.2023.98911.1179

Where do liver injuries stand in the post-COVID-19 era? A review of the connection between long COVID and liver diseases

Iranian Journal of Colorectal Research
مقاله 1، دوره 11، شماره 1، خرداد 2023، صفحه 1-14    اصل مقاله (2.39 M)
نوع مقاله: Review Article
شناسه دیجیتال (DOI): 10.30476/acrr.2023.98911.1179
نویسندگان
Somayeh Igder1؛ Mozhdeh Zamani2؛ Omid Vakili3؛ Morvarid Siri4؛ Mojtaba Rashidi5؛ Seyed Vahid Hosseini6؛ Pooneh Mokarram* 7
1Department of Clinical Biochemistry, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
2Autophagy research center, Shiraz University of medical sciences, Shiraz, Iran
3Department of Clinical Biochemistry, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran
4Autophagy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
5Department of Clinical Biochemistry, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
6Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
7Autophagy Research center, Shiraz University of Medical Sciences, shiraz, Iran.
چکیده
Context: The uninterrupted dissemination and transmission of COVID-19 brought enormous jeopardy and public-health urgency during past three years. Some patients, who recovered from the infection, develop persistent symptoms and organ dysfunction for weeks or even months; conditions that are called long COVID. Among multiple COVID-related complications, positive individuals suffer from lesser to greater degrees of intrahepatic and extrahepatic complications that principally mediated by ACE2 receptors. Evidence acquisition: We reviewed manuscripts from PubMed, Google Scholar and Web of Science on underlying COVID-19-linked clinical relevance and potential pathogenesis of liver complications during short COVID, as well as long COVID with no time limitation. Results: Liver impairment needs a large-scale and persistent follow-up as it may be multivariate in nature. During COVID-19, physicians must assess whether hepatopathy is associated with hepatic disorders, medications utilized for the COVID-19 therapy, viral antigenic outcomes progression to a complicated course. In the context of COVID-19, physicians report that potential pathophysiological approaches to hepatic failure in critical patients further could be leading to deep vein thrombosis, myocardial infarction, venous thromboembolism, and acute kidney injury. These complications might be either reversible, or irreversible with extended manifestations that mostly occur as a consequence of long COVID in the post-COVID era. Moreover, pre-existing cardiovascular and digestive tract problems tend to be highly correlated with adverse clinical outcomes and the highest fatality rate. Potential drug-disease interactions adversely influencing COVID-19 subjects and persistent comorbidities are also getting a major consideration. Conclusion: The assessment of whether the upshot of hepatic-associated co-morbidities in COVID-19 status can improve an acceptable personalized therapeutic strategy considering these specific tropisms.
کلیدواژه‌ها
COVID-19 infection؛ Hepatic diseases؛ Post-COVID syndrome
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