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Boroun, Arman, Gholamhosseinian, Hamid, Montazerabadi, Alireza, Molana, Seyed Hadi, Pashaei, Fakhereh. (1402). Optimizing the Radiation Treatment Planning of Brain Tumors by Integration of Functional MRI and White Matter Tractography. سامانه مدیریت نشریات علمی, 13(3), 239-250. doi: 10.31661/jbpe.v0i0.2210-1547
Arman Boroun; Hamid Gholamhosseinian; Alireza Montazerabadi; Seyed Hadi Molana; Fakhereh Pashaei. "Optimizing the Radiation Treatment Planning of Brain Tumors by Integration of Functional MRI and White Matter Tractography". سامانه مدیریت نشریات علمی, 13, 3, 1402, 239-250. doi: 10.31661/jbpe.v0i0.2210-1547
Boroun, Arman, Gholamhosseinian, Hamid, Montazerabadi, Alireza, Molana, Seyed Hadi, Pashaei, Fakhereh. (1402). 'Optimizing the Radiation Treatment Planning of Brain Tumors by Integration of Functional MRI and White Matter Tractography', سامانه مدیریت نشریات علمی, 13(3), pp. 239-250. doi: 10.31661/jbpe.v0i0.2210-1547
Boroun, Arman, Gholamhosseinian, Hamid, Montazerabadi, Alireza, Molana, Seyed Hadi, Pashaei, Fakhereh. Optimizing the Radiation Treatment Planning of Brain Tumors by Integration of Functional MRI and White Matter Tractography. سامانه مدیریت نشریات علمی, 1402; 13(3): 239-250. doi: 10.31661/jbpe.v0i0.2210-1547

Optimizing the Radiation Treatment Planning of Brain Tumors by Integration of Functional MRI and White Matter Tractography

Journal of Biomedical Physics and Engineering
دوره 13، شماره 3، شهریور 2023، صفحه 239-250    اصل مقاله (1.35 M)
نوع مقاله: Original Research
شناسه دیجیتال (DOI): 10.31661/jbpe.v0i0.2210-1547
نویسندگان
Arman Boroun1؛ Hamid Gholamhosseinian2؛ Alireza Montazerabadi2؛ Seyed Hadi Molana3؛ Fakhereh Pashaei* 1
1Radiation Sciences Research Center (RSRC), Aja University of Medical Sciences, Tehran, Iran
2Medical Physics Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
3Department of Radiation Oncology, Aja University of Medical Sciences, Tehran, Iran
چکیده
Background: Diffusion tensor imaging (DTI) and functional magnetic resonance imaging (fMRI) present the ability to selectively protect functional regions and fiber tracts of the brain when brain tumors are treated with radiotherapy.
Objective: This study aimed to assess whether the incorporation of fMRI and DTI data into the radiation treatment planning process of brain tumors could prevent the neurological parts of the brain from high doses of radiation.
Material and Methods: In this investigational theoretical study, the fMRI and DTI data were obtained from eight glioma patients. This patient-specific fMRI and DTI data were attained based on tumor location, the patient’s general conditions, and the importance of the functional and fiber tract areas. The functional regions, fiber tracts, anatomical organs at risk, and the tumor were contoured for radiation treatment planning. Finally, the radiation treatment planning with and without fMRI & DTI information was obtained and compared.
Results: The mean dose to the functional areas and the maximum doses were reduced by 25.36% and 18.57% on fMRI & DTI plans compared with the anatomical plans. In addition, 15.59% and 20.84% reductions were achieved in the mean and maximum doses of the fiber tracts, respectively. 
Conclusion: This study demonstrated the feasibility of using fMRI and DTI data in radiation treatment planning to maximize radiation protection of the functional cortex and fiber tracts. The mean and maximum doses significantly decreased to neurologically relevant brain regions, resulting in reducing the neuro-cognitive complications and improving the patient’s quality of life.
کلیدواژه‌ها
Brain Neoplasms؛ fMRI؛ Diffusion Tensor Imaging؛ Radiation Therapy؛ Glioma؛ MRI
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مراجع
  1. Sontheimer H. Brain Tumors. In: Diseases of the Nervous System. San Diego: Academic Press; 2015. p. 259-88.
  2. Pignatti F, Van Den Bent M, Curran D, Debruyne C, Sylvester R, Therasse P, et al. Prognostic factors for survival in adult patients with cerebral low-grade glioma. J Clin Oncol. 2002;20(8):2076-84. doi: 10.1200/JCO.2002.08.121. PubMed PMID: 11956268.
  3. Chang J, Narayana A. Functional MRI for radiotherapy of gliomas. Technol Cancer Res Treat. 2010;9(4):347-58. doi: 10.1177/153303461000900405. PubMed PMID: 20626201.
  4. Wang M, Ma H, Wang X, Guo Y, Xia X, Xia H, et al. Integration of BOLD-fMRI and DTI into radiation treatment planning for high-grade gliomas located near the primary motor cortexes and corticospinal tracts. Radiat Oncol. 2015;10:64. doi: 10.1186/s13014-015-0364-1. PubMed PMID: 25884395. PubMed PMCID: PMC4357178.
  5. Makale MT, McDonald CR, Hattangadi-Gluth JA, Kesari S. Mechanisms of radiotherapy-associated cognitive disability in patients with brain tumours. Nat Rev Neurol. 2017;13(1):52-64. doi: 10.1038/nrneurol.2016.185. PubMed PMID: 27982041. PubMed PMCID: PMC5805381.
  6. Baron Nelson M, Compton P, Patel SK, Jacob E, Harper R. Central nervous system injury and neurobiobehavioral function in children with brain tumors: a review of the literature. Cancer Nurs. 2013;36(2):E31-47. doi: 10.1097/NCC.0b013e31825d1eb0. PubMed PMID: 22781957. PubMed PMCID: PMC5964978.
  7. Son Y, Yang M, Wang H, Moon C. Hippocampal dysfunctions caused by cranial irradiation: a review of the experimental evidence. Brain Behav Immun. 2015;45:287-96. doi: 10.1016/j.bbi.2015.01.007. PubMed PMID: 25596174.
  8. Liu R, Page M, Solheim K, Fox S, Chang SM. Quality of life in adults with brain tumors: current knowledge and future directions. Neuro Oncol. 2009;11(3):330-9. doi: 10.1215/15228517-2008-093. PubMed PMID: 19001097. PubMed PMCID: PMC2718978.
  9. McDuff SG, Taich ZJ, Lawson JD, Sanghvi P, Wong ET, Barker FG, et al. Neurocognitive assessment following whole brain radiation therapy and radiosurgery for patients with cerebral metastases. J Neurol Neurosurg Psychiatry. 2013;84(12):1384-91. doi: 10.1136/jnnp-2013-305166. PubMed PMID: 23715918.
  10. Bailey CC, Gnekow A, Wellek S, Jones M, Round C, Brown J, et al. Prospective randomised trial of chemotherapy given before radiotherapy in childhood medulloblastoma. International Society of Paediatric Oncology (SIOP) and the (German) Society of Paediatric Oncology (GPO): SIOP II. Med Pediatr Oncol. 1995;25(3):166-78. doi: 10.1002/mpo.2950250303. PubMed PMID: 7623725.
  11. Gkogkou P, Ajithkumar TV. Advances in Radiotherapy for Pediatric Brain Tumours. In: Pediatric Neurosurgery for Clinicians. Cham: Springer International Publishing; 2022. p. 813-38.
  12. Padovani L, André N, Constine LS, Muracciole X. Neurocognitive function after radiotherapy for paediatric brain tumours. Nat Rev Neurol. 2012;8(10):578-88. doi: 10.1038/nrneurol.2012.182. PubMed PMID: 22964509.
  13. Macedoni-Luksic M, Jereb B, Todorovski L. Long-term sequelae in children treated for brain tumors: impairments, disability, and handicap. Pediatr Hematol Oncol. 2003;20(2):89-101. doi: 10.1080/0880010390158595. PubMed PMID: 12554520.
  14. Ajithkumar T, Price S, Horan G, Burke A, Jefferies S. Prevention of radiotherapy-induced neurocognitive dysfunction in survivors of paediatric brain tumours: the potential role of modern imaging and radiotherapy techniques. Lancet Oncol. 2017;18(2):e91-100. doi: 10.1016/S1470-2045(17)30030-X. PubMed PMID: 28214420.
  15. Rutkowski S, Bode U, Deinlein F, Ottensmeier H, Warmuth-Metz M, Soerensen N, et al. Treatment of early childhood medulloblastoma by postoperative chemotherapy alone. N Engl J Med. 2005;352(10):978-86. doi: 10.1056/NEJMoa042176. PubMed PMID: 15758008.
  16. Pantelis E, Papadakis N, Verigos K, Stathochristopoulou I, Antypas C, Lekas L, et al. Integration of functional MRI and white matter tractography in stereotactic radiosurgery clinical practice. Int J Radiat Oncol Biol Phys. 2010;78(1):257-67. doi: 10.1016/j.ijrobp.2009.10.064. PubMed PMID: 20421146.
  17. Stancanello J, Cavedon C, Francescon P, Causin F, Avanzo M, Colombo F, et al. BOLD fMRI integration into radiosurgery treatment planning of cerebral vascular malformations. Med Phys. 2007;34(4):1176-84. doi: 10.1118/1.2710326. PubMed PMID: 17500448.
  18. Maruyama K, Kamada K, Shin M, Itoh D, Masutani Y, Ino K, et al. Optic radiation tractography integrated into simulated treatment planning for Gamma Knife surgery. J Neurosurg. 2007;107(4):721-6. doi: 10.3171/JNS-07/10/0721. PubMed PMID: 17937214.
  19. Maruyama K, Kamada K, Ota T, Koga T, Itoh D, Ino K, et al. Tolerance of pyramidal tract to gamma knife radiosurgery based on diffusion-tensor tractography. Int J Radiat Oncol Biol Phys. 2008;70(5):1330-5. doi: 10.1016/j.ijrobp.2007.08.010. PubMed PMID: 17935904.
  20. Sun L, Qu B, Wang J, Ju Z, Zhang Z, Cui Z, et al. Integration of Functional MRI and White Matter Tractography in CyberKnife Radiosurgery. Technol Cancer Res Treat. 2017;16(6):850-6. doi: 10.1177/1533034617705283. PubMed PMID: 28425348; PMCID: PMC5762040.
  21. Fisicaro R, Nicole M. Functional MRI: Petrovich Brennan and Andrei I Holodny. Chapter 29. In Handbook of Neuro-Oncology Neuroimaging. 2nd Edition. San Diego: Academic Press; 2016. p. 317-325.
  22. Shevzov-Zebrun N, Brennan NM, Peck KK, Holodny AI. Advanced Functional Imaging: fMRI, PET, and MEG. In: Image-Guided Neurosurgery. Academic Press; 2015. p. 63-89.
  23. Mahdavi A, Houshmand S, Oghabian MA, Zarei M, Mahdavi A, Shoar MH, Ghanaati H. Developing optimized fMRI protocol for clinical use: comparison of different language paradigms. J Magn Reson Imaging. 2011;34(2):413-9. doi: 10.1002/jmri.22604. PubMed PMID: 21780233.
  24. Liu WC, Schulder M, Narra V, Kalnin AJ, Cathcart C, Jacobs A, et al. Functional magnetic resonance imaging aided radiation treatment planning. Med Phys. 2000;27(7):1563-72. doi: 10.1118/1.599022. PubMed PMID: 10947259.
  25. Sours Rhodes C, Zhang H, Patel K, Mistry N, Kwok Y, D’Souza WD, et al. The Feasibility of Integrating Resting-State fMRI Networks into Radiotherapy Treatment Planning. J Med Imaging Radiat Sci. 2019;50(1):119-28. doi: 10.1016/j.jmir.2018.09.003. PubMed PMID: 30777232.
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