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Bevelacqua, Joseph John, Ghadimi Moghadam, Abdolkarim, Mortazavi, Seyed Alireza, Jafarzadeh, Abdollah, Haghani, Masoud, Kaveh-Ahangar, Azim, Ghadimi-Moghadam, Ali. (1403). Time Reveals the Truth! What Treatments for COVID-19 Were Quickly Abandoned, and Which Methods, Contrary to Popular Belief, Are Still Flourishing?. سامانه مدیریت نشریات علمی, 14(6), 599-606. doi: 10.31661/jbpe.v0i0.2206-1514
Joseph John Bevelacqua; Abdolkarim Ghadimi Moghadam; Seyed Alireza Mortazavi; Abdollah Jafarzadeh; Masoud Haghani; Azim Kaveh-Ahangar; Ali Ghadimi-Moghadam. "Time Reveals the Truth! What Treatments for COVID-19 Were Quickly Abandoned, and Which Methods, Contrary to Popular Belief, Are Still Flourishing?". سامانه مدیریت نشریات علمی, 14, 6, 1403, 599-606. doi: 10.31661/jbpe.v0i0.2206-1514
Bevelacqua, Joseph John, Ghadimi Moghadam, Abdolkarim, Mortazavi, Seyed Alireza, Jafarzadeh, Abdollah, Haghani, Masoud, Kaveh-Ahangar, Azim, Ghadimi-Moghadam, Ali. (1403). 'Time Reveals the Truth! What Treatments for COVID-19 Were Quickly Abandoned, and Which Methods, Contrary to Popular Belief, Are Still Flourishing?', سامانه مدیریت نشریات علمی, 14(6), pp. 599-606. doi: 10.31661/jbpe.v0i0.2206-1514
Bevelacqua, Joseph John, Ghadimi Moghadam, Abdolkarim, Mortazavi, Seyed Alireza, Jafarzadeh, Abdollah, Haghani, Masoud, Kaveh-Ahangar, Azim, Ghadimi-Moghadam, Ali. Time Reveals the Truth! What Treatments for COVID-19 Were Quickly Abandoned, and Which Methods, Contrary to Popular Belief, Are Still Flourishing?. سامانه مدیریت نشریات علمی, 1403; 14(6): 599-606. doi: 10.31661/jbpe.v0i0.2206-1514

Time Reveals the Truth! What Treatments for COVID-19 Were Quickly Abandoned, and Which Methods, Contrary to Popular Belief, Are Still Flourishing?

Journal of Biomedical Physics and Engineering
دوره 14، شماره 6، اسفند 2024، صفحه 599-606    اصل مقاله (632.14 K)
نوع مقاله: Commentary
شناسه دیجیتال (DOI): 10.31661/jbpe.v0i0.2206-1514
نویسندگان
Joseph John Bevelacqua1؛ Abdolkarim Ghadimi Moghadam2؛ Seyed Alireza Mortazavi3؛ Abdollah Jafarzadeh4؛ Masoud Haghani* 5؛ Azim Kaveh-Ahangar6؛ Ali Ghadimi-Moghadam7
1Bevelacqua Resources, Richland, WA, United States
2Pediatric Infectious Ward, Yasuj University of Medical Sciences, Yasuj, Iran
3School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
4Department of Immunology, School of Medicine, Kerman University of Medical Sciences, Kerman, Iran
5Department of Radiology, School of Paramedical Sciences, Shiraz University of Medical Sciences, Shiraz, Iran
6Vice-chancellery for Research, Shiraz University of Medical Sciences, Shiraz, Iran
7Faculty of Medicine, Szeged University, Szeged, Hungary
چکیده
During the early days of the COVID-19 pandemic, low dose radiation therapy (LDRT) was proposed as a potentially effective treatment method. To minimize potential toxicity, the initial treatment approach involved a few mGy of adapting radiation followed by a single 250 mGy whole lung challenging dose. However, antiviral drugs were also introduced as a promising treatment option, which were thought to have the potential to revolutionize the management of the crisis. Despite early warnings, many physicians did not fully consider the key point that, in contrast with LDRT, antiviral drug treatments can result in strong selective pressure on the virus. This can lead to the emergence of new SARS-CoV-2 variants, a phenomenon that can have serious global consequences. After more than two years, the truth has been revealed: the WHO Guideline Development Group has advised against the use of remdesivir, a widely used antiviral medication, for COVID-19. Meanwhile, a growing body of evidence suggests that LDRT can be a promising, low-risk approach for avoiding or delaying invasive respiratory support in COVID-19 patients. Although there is substantial supporting documentation, more high-quality, controlled, and randomized double-blind clinical trials are needed to further investigate the efficacy and potential therapeutic mechanisms of LDRT for COVID-19.

تازه های تحقیق

Joseph John Bevelacqua (PubMed)

Masoud Haghani (Google Scholar)

کلیدواژه‌ها
COVID-19؛ SARS-CoV-2؛ Pneumonia؛ Low Dose Radiation؛ Remdesivir
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