LinkedIn

 آمار

تعداد نشریات20
تعداد شماره‌ها1,149
تعداد مقالات10,518
تعداد مشاهده مقاله45,415,488
تعداد دریافت فایل اصل مقاله11,291,280
Ghapanchi, Janan, Farahmand, Hanieh, Bazargani, Abdollah, Zekavat, Seyed Omidreza, Lavaee, Fatemeh, Ojaghi, Amir Hossein. (1402). Evaluation of Staphylococcus Aureus and Pseudomonas Aeruginosa in Saliva of Patients with Acute Myeloid Leukemia. سامانه مدیریت نشریات علمی, 25(1), 45-50. doi: 10.30476/dentjods.2023.97098.1989
Janan Ghapanchi; Hanieh Farahmand; Abdollah Bazargani; Seyed Omidreza Zekavat; Fatemeh Lavaee; Amir Hossein Ojaghi. "Evaluation of Staphylococcus Aureus and Pseudomonas Aeruginosa in Saliva of Patients with Acute Myeloid Leukemia". سامانه مدیریت نشریات علمی, 25, 1, 1402, 45-50. doi: 10.30476/dentjods.2023.97098.1989
Ghapanchi, Janan, Farahmand, Hanieh, Bazargani, Abdollah, Zekavat, Seyed Omidreza, Lavaee, Fatemeh, Ojaghi, Amir Hossein. (1402). 'Evaluation of Staphylococcus Aureus and Pseudomonas Aeruginosa in Saliva of Patients with Acute Myeloid Leukemia', سامانه مدیریت نشریات علمی, 25(1), pp. 45-50. doi: 10.30476/dentjods.2023.97098.1989
Ghapanchi, Janan, Farahmand, Hanieh, Bazargani, Abdollah, Zekavat, Seyed Omidreza, Lavaee, Fatemeh, Ojaghi, Amir Hossein. Evaluation of Staphylococcus Aureus and Pseudomonas Aeruginosa in Saliva of Patients with Acute Myeloid Leukemia. سامانه مدیریت نشریات علمی, 1402; 25(1): 45-50. doi: 10.30476/dentjods.2023.97098.1989

Evaluation of Staphylococcus Aureus and Pseudomonas Aeruginosa in Saliva of Patients with Acute Myeloid Leukemia

Journal of Dentistry
مقاله 6، دوره 25، شماره 1 - شماره پیاپی 82، خرداد 2024، صفحه 45-50    اصل مقاله (188.23 K)
نوع مقاله: Original Article
شناسه دیجیتال (DOI): 10.30476/dentjods.2023.97098.1989
نویسندگان
Janan Ghapanchi1؛ Hanieh Farahmand2؛ Abdollah Bazargani3؛ Seyed Omidreza Zekavat4؛ Fatemeh Lavaee* 5؛ Amir Hossein Ojaghi6
1Oral and Dental Diseases Research Center, Dept. of Oral Medicine, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.
2Post Graduate Student, Dept. of Oral and Maxillofacial Medicine, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.
3Dept. of Medicine of Microbiology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
4Associate professor,Pediatric Department, Division of Pediatric Hematology and oncology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
5Dep.t of Pediatric, Division of Pediatric Hematology and oncology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
6Dental Research Committee, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.
چکیده
Statement of the Problem: Patients with leukemia are prone to infectious and often life-threatening complications. Evidence suggests that a specific oral microbiota may contribute to septicemia, which can delay antineoplastic treatment, compromise treatment efficacy, or even endanger patients' lives
Purpose: This study investigated the prevalence of Staphylococcus aureus and Pseudomonas aeruginosa in the saliva of patients with acute myeloid leukemia who were candidates for bone marrow transplantation.
Materials and Method: This cross-sectional study was conducted in 2019 in the Hematology-Oncology Department of Namazi Hospital, Shiraz University of Medical Sciences. The study included 28 patients with acute myeloid leukemia eligible for bone marrow transplantation as the case group and age- and sex-matched healthy individuals as the control group. Unstimulated saliva samples were collected to determine the frequency of Staphylococcus aureus and Pseudomonas aeruginosa. Data were analyzed using SPSS version 18, the chi-square test, and the independent t-test.
Results: In the patients with acute myeloid leukemia, 26 (86%) were positive for Staph-ylococcus aureus and 18 (60%) were positive for Pseudomonas aeruginosa. In the healthy group, 11 (22.9%) were positive for Staphylococcus aureus and 3 (6.2%) were positive for Pseudomonas aeruginosa. The frequency of Pseudomonas aeruginosa and Staphylococcus aureus in the saliva samples of patients with acute myeloid leukemia was significantly higher than in the healthy control subjects (p value < 0.05). Chi-square test showed no significant association between age and the frequency of bacteria (p value= 0.27).
Conclusion: In the current study, the frequency of Staphylococcus aureus and Pseudomonas aeruginosa in the saliva of patients with acute myeloid leukemia was higher than in the healthy control group.

تازه های تحقیق

Fatemeh Lavaee (Google Scholar)

کلیدواژه‌ها
Staphylococcus aureus؛ Pseudomonas aeruginosa؛ Saliva؛ Acute myeloid leukemia
سایر فایل های مرتبط با مقاله
مراجع
  • Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global cancer statistics 2020: Globocan Estimates of Incidence and Mortality World wide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71: 209-249.
  • Sorror ML, Storer BE, Nyland J, Estey EH. Revised acute myeloid leukemia composite model using the 2017 European LeukemiaNet risk classification. JAMA Oncol. 2019; 5: 1062-1064.
  • Taicz M, Pérez MG, Reijtman V, Mastroianni A, Escarra F, García ME, et al. Epidemiology and risk factors for prolonged hospital length of stay in children with leukemia and bacteremia. Cohort study. Rev Chilena Infectol. 2018; 35: 233-238.
  • Shi W, Tian J, Xu H, Zhou Q, Qin M. Distinctions and associations between the microbiota of saliva and supragingival plaque of permanent and deciduous teeth. PLoS One. 2018; 13: e0200337.
  • Graves DT, Corrêa JD, Silva TA. The oral microbiota is modified by systemic diseases. J Dent Res. 2019; 98: 148-156.
  • Ndlovu KCZ, Swe Swe-Han K, Assounga A. Association of staphylococcus nasal colonization and HIV in end-stage renal failure patients undergoing peritoneal dialysis. Ren Fail. 2019; 41: 303-313.
  • Pitt TL, Simpson AJ. Pseudomonas aeruginosa and Bu-rkholderia spp. In: Hawkey PM, Gillespie SH, editors. Principles and Practice of Clinical Bacteriology. 1th ed. Chichester: John Wiley and Sons; 2006. p. 426-443.
  • Diggle SP, Whiteley M. Microbe Profile: Pseudomonas aeruginosa: opportunistic pathogen and lab rat. Microbiology. 2020; 166: 30.
  • Qin S, Xiao W, Zhou C, Pu Q, Deng X, Lan L, et al. Pseudomonas aeruginosa: pathogenesis, virulence factors, antibiotic resistance, interaction with host, technology advances and emerging therapeutics. Signal Transduct Target Ther. 2022; 7: 199.
  • Satlin MJ, Walsh TJ. Multidrug-resistant Enterobacteriaceae, Pseudomonas aeruginosa, and vancomycin-resistant Enterococcus: Three major threats to hematopoietic stem cell transplant recipients. Transpl Infect Dis. 2017; 19: 10.1111/tid.12762. 
  • Kulkarni HS, Tsui K, Sunder S, Ganninger A, Tague LK, Witt CA, et al. Pseudomonas aeruginosa and acute rejection independently increase the risk of donor-specific antibodies after lung transplantation. Am J Transplant. 2020; 20: 1028-1038.
  • Collin BA, Leather HL, Wingard JR, Ramphal R. Evolution, incidence, and susceptibility of bacterial bloodstream isolates from 519 bone marrow transplant patients. Clin Infect Dis. 2001; 33: 947-953.
  • Olszewska K, Mielnik-Błaszczak M. An assessment of the number of cariogenic bacteria in the saliva of children with chemotherapy-induced neutropenia. Adv Clin Exp Med. 2016; 25: 11-19.
  • Vozza I, Caldarazzo V, Ottolenghi L. Changes in microflora in dental plaque from cancer patients undergoing chemotherapy and the relationship of these changes with mucositis: A pilot study. Med Oral Patol Oral Cir Bucal. 2015; 20: e259-e266. 
  • Jackson MS. Staphylococci in the oral flora of healthy children and those receiving treatment for malignant disease. Microbial Ecol Health and Dis.2000; 12: 60-64.
  • Schimpff SC, Greene WH, Young VM, Wiernik PH. Significance of Pseudomonas aeruginosa in the patient with leukemia or lymphoma. J Infect Dis. 1974; 130(Supplement): S24-S31.
  • Balletto E, Mikulska M. Bacterial infections in hematopoietic stem cell transplant recipients. Mediterr J Hematol Infect Dis. 2015; 7: e2015045.
  • Association WM. World medical association declaration of Helsinki. Available at: http://www.wma.net/en/30publications/10policies/b3/index html.
  • Relvas M, López-Jarana P, Monteiro L, Pacheco JJ, Braga AC, Salazar F. Study of Prevalence, Severity and Risk Factors of Periodontal Disease in a Portuguese Population. J Clin Med. 2022; 11: 3728.
  • Bellagambi FG, Lomonaco T, Salvo P, Vivaldi F, Hangouët M, Ghimenti S, et al. Saliva sampling: methods and devices. An Overview. TrAC Trends Anal. Chem. 2020; 124: 115781.
  • Gooch JW. Streak Plate Method. In: Gooch JW, editor. Encyclopedic Dictionary of Polymers. 1th ed. New York, NY: Springer New York; 2011. p. 926.
  • Bogusławska-Kapała A, Hałaburda K, Rusyan E, Gołąbek H, Strużycka I. Oral health of adult patients undergoing hematopoietic cell transplantation. Pre-transplant assessment and care. Ann Hematol. 2017; 96: 1135-1145.
  • Al-Kuhla HWA, Al-Aswad FD. Oral manifestations, microbial study and salivary IgA study in lymphoma patients receiving chemotherapy. J Baghdad Coll Dent. 2011; 23: 56-60.
  • Eduardo FdP, Bezinelli LM, Gobbi M, Santos V, Maluf F, Corrêa L. Severe oral infection caused by Pseudomon as aeruginosa effectively treated with methylene bluem-ediated photodynamic inactivation. Photodiagnosis Photodyn Ther. 2019; 26: 284-286.
  • Kang CK, Kwak YG, Park Y, Song KH, Kim ES, Jung SI, et al. Gender affects prognosis of methicillin-resistant Staphylococcus aureus bacteremia differently depending on the severity of underlying disease. Eur J Clin Microbiol Infect Dis. 2018; 37: 1119-1123.
  • Villafuerte KRV, Martinez CdJH, Dantas FT, Carrara HHA, Dos Reis FJC, Palioto DB. The impact of chemotherapeutic treatment on the oral microbiota of patients with cancer: a systematic review. Oral Surg Oral Med Oral Pathol Oral Radio. 2018; 125: 552-566.
  • Napeñas JJ, Brennan MT, Bahrani-Mougeot FK, Fox PC, Lockhart PB. Relationship between mucositis and changes in oral microflora during cancer chemotherapy. Oral Surg Oral Med Oral Patho Oral Radio Endo. 2007; 103: 48-59.
  • Mathews J, Patel M. Bacterial endotoxins and microorganisms in the oral cavities of patients on cancer therapy. Microb Pathog. 2018;123:190-5.
  • Wingard JR, Majhail NS, Brazauskas R, Wang Z, Sobocinski KA, Jacobsohn D, et al. Long-term survival and late deaths after allogeneic hematopoietic cell transplantation. J Clin Oncol. 2011; 29: 2230.
  • Georgakopoulou EA, Achtari MD, Afentoulide N. Dental management of patients before and after renal transplantation. Stomatologija. 2011; 13: 107-112.
  • Párkányi L, Vályi P, Nagy K, Fráter M. Odontogenic foci and systemic diseases: A review. Orv Hetil. 2018; 159: 415-422.
  • Laheij AM, de*Soet JJ, von*dem Borne PA, Kuijper EJ, Kraneveld EA, van*Loveren C, et al. Oral bacteria and yeasts in relationship to oral ulcerations in hematopoietic stem cell transplant recipients. Support Care Cancer. 2012; 20: 3231-3240. 
  • Mawardi H, Treister N, Felemban O, Alamoudi W, Algohary G, Alsultan A, et al. Current practice of oral care for hematopoietic stem cell transplant patients: A survey of the Eastern Mediterranean Blood and Marrow transplantation group. Hematol Oncol Stem Cell Ther. 2023; 16: 42-51.
آمار
تعداد مشاهده مقاله: 3,068
تعداد دریافت فایل اصل مقاله: 457


سامانه مدیریت نشریات علمی. قدرت گرفته از سیناوب