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Yonemura, Yutaka, Ishibashi, Haruaki, Mizumoto, Akiyoshi, Fujita, Takuji, Liu, Yang, Wakama, Satoshi, Sako, Syouzou, Takao, Nobuyuki, Kitai, Toshiyuki, Katayama, Kanji, Kamada, Yasuyuki, Taniguchi, Keizou, Fujimoto, Daisuke. (1401). Indications for Cytoreductive Surgery Plus HIPEC in Patients with Colorectal Cancer and Peritoneal Metastasis. سامانه مدیریت نشریات علمی, 11(1), 22-32. doi: 10.30476/acrr.2023.98167.1172
Yutaka Yonemura; Haruaki Ishibashi; Akiyoshi Mizumoto; Takuji Fujita; Yang Liu; Satoshi Wakama; Syouzou Sako; Nobuyuki Takao; Toshiyuki Kitai; Kanji Katayama; Yasuyuki Kamada; Keizou Taniguchi; Daisuke Fujimoto. "Indications for Cytoreductive Surgery Plus HIPEC in Patients with Colorectal Cancer and Peritoneal Metastasis". سامانه مدیریت نشریات علمی, 11, 1, 1401, 22-32. doi: 10.30476/acrr.2023.98167.1172
Yonemura, Yutaka, Ishibashi, Haruaki, Mizumoto, Akiyoshi, Fujita, Takuji, Liu, Yang, Wakama, Satoshi, Sako, Syouzou, Takao, Nobuyuki, Kitai, Toshiyuki, Katayama, Kanji, Kamada, Yasuyuki, Taniguchi, Keizou, Fujimoto, Daisuke. (1401). 'Indications for Cytoreductive Surgery Plus HIPEC in Patients with Colorectal Cancer and Peritoneal Metastasis', سامانه مدیریت نشریات علمی, 11(1), pp. 22-32. doi: 10.30476/acrr.2023.98167.1172
Yonemura, Yutaka, Ishibashi, Haruaki, Mizumoto, Akiyoshi, Fujita, Takuji, Liu, Yang, Wakama, Satoshi, Sako, Syouzou, Takao, Nobuyuki, Kitai, Toshiyuki, Katayama, Kanji, Kamada, Yasuyuki, Taniguchi, Keizou, Fujimoto, Daisuke. Indications for Cytoreductive Surgery Plus HIPEC in Patients with Colorectal Cancer and Peritoneal Metastasis. سامانه مدیریت نشریات علمی, 1401; 11(1): 22-32. doi: 10.30476/acrr.2023.98167.1172

Indications for Cytoreductive Surgery Plus HIPEC in Patients with Colorectal Cancer and Peritoneal Metastasis

Iranian Journal of Colorectal Research
مقاله 3، دوره 11، شماره 1، خرداد 2023، صفحه 22-32    اصل مقاله (788.39 K)
نوع مقاله: Research/Original Article
شناسه دیجیتال (DOI): 10.30476/acrr.2023.98167.1172
نویسندگان
Yutaka Yonemura* 1، 2، 3؛ Haruaki Ishibashi2؛ Akiyoshi Mizumoto3؛ Takuji Fujita2؛ Yang Liu2؛ Satoshi Wakama2؛ Syouzou Sako2؛ Nobuyuki Takao3؛ Toshiyuki Kitai2؛ Kanji Katayama2؛ Yasuyuki Kamada2؛ Keizou Taniguchi4؛ Daisuke Fujimoto4
1Asian School of Peritoneal Surface Malignancy Treatment, Kyoto City, Kyoto Prefecture, Japan
2Department of Regional Cancer Therapy, Peritoneal Surface Malignancy Treatment Center, Kishiwada Tokushukai Hospital, Kishiwada City, Osaka Prefecture, Japan
3Department of Regional Cancer Therapy, Peritoneal Dissemination Center, Kusatsu General Hospital, Kusatsu City, Shiga Prefecture, Japan
4Department of Surgery, Mizonokuchi Hospital, Teikyo University, School of Medicine, Kawasaki, Kanagawa, Japan
چکیده
Background: Comprehensive treatment (COMPT) consisting of cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) improves survival in selected patients with peritoneal metastasis (PM) from colorectal cancer (CRC). The present study aimed to clarify clinicopathologic parameters that are indications for COMPT in CRC patients with PM.
Methods: Between 2006 and 2021, 447 patients were eligible for COMPT among 906 CRC patients with PM. Clinicopathologic parameters contributing to long-term survival and cure were analyzed.
Results: A log-rank test showed a significant survival difference for peritoneal cancer index (PCI) (≤12 vs. ≥13, P<0.0001), completeness of cytoreduction (CCR) score (CCR-0 vs. CCR-1, P<0.0001), small bowel (SB)-PCI (≤2 vs. ≥3), liver/lung metastasis (LLM) (negative vs. positive, P=0.002), histologic type (differentiated type vs. signet ring cell (SRC) subtype, P=0.008), number of involved peritoneal sectors (≤6 vs. ≥7), HIPEC (done vs. not done) and postoperative complication (grades 0–2 vs. grades 3–5, P<0.0001). Muti-variate analyses revealed that CCR score (CCR-0 vs. CCR-1, P<0.0001), SB-PCI score (≤2 vs. ≥3, P<0.005), LLM (negative vs. positive, P=0.002), and HIPEC (performed vs. not done) were independent prognostic factors. The incidence of postoperative grade 3–5 complications was 19.0% (85/447), and the mortality rate was 2.0% (9/447). One hundred seventy patients fulfilled the following clinicopathologic factors: PCI≤12, SB-PCI≤2, number of involved peritoneal sectors ≤6, no LLM, differentiated histologic type, and CCR-0. The median survival time of these patients was 5.5 years, and five and ten-year survival rates were 57.8% and 24.6%, respectively. Postoperative grade 3, 4, and 5 complications in these 170 patients occurred in 9 (5.3%), 15 (8.8%), and 1 (0.6%), respectively. Cured patients were defined as those alive without recurrence more than five years after CRS. All of the cured patients underwent CCR-0 resection. The PCI and SB-PCI of these 23 patients were ≤12 and ≤2, respectively.
Conclusion: Among CRC patients with PM, COMPT with CCR-0 resection is indicated for PCI ≤12, SB-PCI ≤2, number of involved peritoneal sectors ≤6, no LLM, and differentiated histologic type. 
کلیدواژه‌ها
Peritoneal metastasis؛ Colorectal cancer؛ Peritoneal Neoplasms؛ Percutaneous Coronary Intervention؛ Hyperthermic Intraperitoneal Chemotherapy
مراجع
  1. Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA: a cancer journal for clinicians. 2021;71 (3):209-49.
  2. Koppe MJ, Boerman OC, Oyen WJ, Bleichrodt RP. Peritoneal carcinomatosis of colorectal origin: incidence and current treatment strategies. Annals of surgery. 2006;243 (2):212-22.
  3. Franko J, Shi Q, Goldman CD, Pockaj BA, Nelson GD, Goldberg RM, et al. Treatment of colorectal peritoneal carcinomatosis with systemic chemotherapy: a pooled analysis of north central cancer treatment group phase III trials N9741 and N9841. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2012;30 (3):263-7.
  4. Franko J, Shi Q, Meyers JP, Maughan TS, Adams RA, Seymour MT, et al. Prognosis of patients with peritoneal metastatic colorectal cancer given systemic therapy: an analysis of individual patient data from prospective randomised trials from the Analysis and Research in Cancers of the Digestive System (ARCAD) database. The Lancet Oncology. 2016;17 (12):1709-19.
  5. Klaver YL, Leenders BJ, Creemers GJ, Rutten HJ, Verwaal VJ, Lemmens VE, et al. Addition of biological therapies to palliative chemotherapy prolongs survival in patients with peritoneal carcinomatosis of colorectal origin. American journal of clinical oncology. 2013;36 (2):157-61.
  6. Sugarbaker PH. Peritonectomy procedures. Annals of surgery. 1995;221 (1):29-42.
  7. Sugarbaker PH, Jablonski KA. Prognostic features of 51 colorectal and 130 appendiceal cancer patients with peritoneal carcinomatosis treated by cytoreductive surgery and intraperitoneal chemotherapy. Annals of surgery. 1995;221 (2):124-32.
  8. Witkamp AJ, de Bree E, Van Goethem R, Zoetmulder FA. Rationale and techniques of intra-operative hyperthermic intraperitoneal chemotherapy. Cancer treatment reviews. 2001;27 (6):365-74.
  9. Elias D, Bonnay M, Puizillou JM, Antoun S, Demirdjian S, El OA, et al. Heated intra-operative intraperitoneal oxaliplatin after complete resection of peritoneal carcinomatosis: pharmacokinetics and tissue distribution. Annals of oncology : official journal of the European Society for Medical Oncology. 2002;13 (2):267-72.
  10. Issels RD. Hyperthermia adds to chemotherapy. European journal of cancer (Oxford, England : 1990). 2008;44 (17):2546-54.
  11. Verwaal VJ, van Ruth S, de Bree E, van Sloothen GW, van Tinteren H, Boot H, et al. Randomized trial of cytoreduction and hyperthermic intraperitoneal chemotherapy versus systemic chemotherapy and palliative surgery in patients with peritoneal carcinomatosis of colorectal cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2003;21 (20):3737-43.
  12. Elias D, Blot F, El Otmany A, Antoun S, Lasser P, Boige V, et al. Curative treatment of peritoneal carcinomatosis arising from colorectal cancer by complete resection and intraperitoneal chemotherapy. Cancer. 2001;92 (1):71-6.
  13. Shen P, Hawksworth J, Lovato J, Loggie BW, Geisinger KR, Fleming RA, et al. Cytoreductive surgery and intraperitoneal hyperthermic chemotherapy with mitomycin C for peritoneal carcinomatosis from nonappendiceal colorectal carcinoma. Annals of surgical oncology. 2004;11 (2):178-86.
  14. Glehen O, Kwiatkowski F, Sugarbaker PH, Elias D, Levine EA, De Simone M, et al. Cytoreductive surgery combined with perioperative intraperitoneal chemotherapy for the management of peritoneal carcinomatosis from colorectal cancer: a multi-institutional study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2004;22 (16):3284-92.
  15. Verwaal VJ, van Ruth S, Witkamp A, Boot H, van Slooten G, Zoetmulder FA. Long-term survival of peritoneal carcinomatosis of colorectal origin. Annals of surgical oncology. 2005;12 (1):65-71.
  16. Elias D, Lefevre JH, Chevalier J, Brouquet A, Marchal F, Classe JM, et al. Complete cytoreductive surgery plus intraperitoneal chemohyperthermia with oxaliplatin for peritoneal carcinomatosis of colorectal origin. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2009;27 (5):681-5.
  17. Yonemura Y, Tsukiyama G, Miyata R, Sako S, Endou Y, Hirano M, et al. Indication of peritonectomy for peritoneal dissemination. Gan to kagaku ryoho Cancer & chemotherapy. 2010;37 (12):2306-11.
  18. Yonemura Y, Elnemr A, Endou Y, Ishibashi H, Mizumoto A, Miura M, et al. Surgical results of patients with peritoneal carcinomatosis treated with cytoreductive surgery using a new technique named aqua dissection. Gastroenterology research and practice. 2012;2012:521487.
  19. Sapareto SA, Dewey WC. Thermal dose determination in cancer therapy. International journal of radiation oncology, biology, physics. 1984;10 (6):787-800.
  20. Jacquet P, Sugarbaker PH. Clinical research methodologies in diagnosis and staging of patients with peritoneal carcinomatosis. Cancer treatment and research. 1996;82:359-74.
  21. Dindo D, Demartines N, Clavien PA. Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Annals of surgery. 2004;240 (2):205-13.
  22. National Comprehensive Cancer Network.Colon Cancer (version 1.2022) [cited 2022. Available from: https://www.nccn.org/guidelines/guidelines-detail?category=1&id=1428. Accessed March 3, 2022. .
  23. Li J, Wang AR, Chen XD, Zhang YX, Pan H, Li SQ. Effect of hyperthermic intraperitoneal chemotherapy in combination with cytoreductive surgery on the prognosis of patients with colorectal cancer peritoneal metastasis: a systematic review and meta-analysis. World journal of surgical oncology. 2022;20 (1):200.
  24. Spiliotis J, Kalles V, Kyriazanos I, Terra A, Prodromidou A, Raptis A, et al. CRS and HIPEC in patients with peritoneal metastasis secondary to colorectal cancer: The small-bowel PCI score as a predictor of survival. Pleura and peritoneum. 2019;4 (4):20190018.
  25. Frøysnes IS, Larsen SG, Spasojevic M, Dueland S, Flatmark K. Complete cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for colorectal peritoneal metastasis in Norway: Prognostic factors and oncologic outcome in a national patient cohort. Journal of surgical oncology. 2016;114 (2):222-7.
  26. Yonemura Y, Prabhu A, Sako S, Ishibashi H, Hirano M, Mizumoto A, et al. Effects of Cytoreductive Surgery Combined with Perioperative Chemotherapy on Long-Term Survivals of Colorectal Cancer Patients with Peritoneal Metastasis, with Special Reference to the Involved Peritoneal Sectors and Organs. Gan to kagaku ryoho Cancer & chemotherapy. 2019;46 (13):1917-21.
  27. Torkzad MR, Casta N, Bergman A, Ahlström H, Påhlman L, Mahteme H. Comparison between MRI and CT in prediction of peritoneal carcinomatosis index (PCI) in patients undergoing cytoreductive surgery in relation to the experience of the radiologist. Journal of surgical oncology. 2015;111 (6):746-51.
  28. Passot G, Dumont F, Goéré D, Arvieux C, Rousset P, Regimbeau JM, et al. Multicentre study of laparoscopic or open assessment of the peritoneal cancer index (BIG-RENAPE). The British journal of surgery. 2018;105 (6):663-7.
  29. Acs M, Dadras A, Blaj S, Leebmann H, Piso P. Selection Criteria for Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy With Special Emphasis on Laparoscopy as an Efficient Tool. In vivo (Athens, Greece). 2022;36 (3):1367-74.
  30. Alzahrani N, Ung L, Valle SJ, Liauw W, Morris DL. Synchronous liver resection with cytoreductive surgery for the treatment of liver and peritoneal metastases from colon cancer: results from an Australian centre. ANZ journal of surgery. 2017;87 (11):E167-e72.
  31. Alzahrani NA, Valle SJ, Fisher OM, Sugarbaker PH, Yonemura Y, Glehen O, et al. Iterative cytoreductive surgery with or without hyperthermic intraperitoneal chemotherapy for colorectal peritoneal metastases: A multi-institutional experience. Journal of surgical oncology. 2019;119 (3):336-46.
  32. Nagata H, Ishihara S, Hata K, Murono K, Kaneko M, Yasuda K, et al. Survival and Prognostic Factors for Metachronous Peritoneal Metastasis in Patients with Colon Cancer. Annals of surgical oncology. 2017;24 (5):1269-80.
  33. van de Vlasakker VCJ, Lurvink RJ, Cashin PH, Ceelen W, Deraco M, Goéré D, et al. The impact of PRODIGE 7 on the current worldwide practice of CRS-HIPEC for colorectal peritoneal metastases: A web-based survey and 2021 statement by Peritoneal Surface Oncology Group International (PSOGI). European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology. 2021;47 (11):2888-92.
  34. Quénet F, Elias D, Roca L, Goéré D, Ghouti L, Pocard M, et al. Cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy versus cytoreductive surgery alone for colorectal peritoneal metastases (PRODIGE 7): a multicentre, randomised, open-label, phase 3 trial. The Lancet Oncology. 2021;22 (2):256-66.
  35. Prabhu A, Brandl A, Wakama S, Sako S, Ishibashi H, Mizumoto A, et al. Effect of oxaliplatin-based chemotherapy on chemosensitivity in patients with peritoneal metastasis from colorectal cancer treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: proof-of-concept study. BJS open. 2021;5 (2).
  36. Pereira F, Serrano A, Manzanedo I, Pérez-Viejo E, González-Moreno S, González-Bayón L, et al. GECOP-MMC: phase IV randomized clinical trial to evaluate the efficacy of hyperthermic intraperitoneal chemotherapy (HIPEC) with mytomicin-C after complete surgical cytoreduction in patients with colon cancer peritoneal metastases. BMC cancer. 2022;22 (1):536.
  37. Kirstein MN, Root SA, Moore MM, Wieman KM, Williams BW, Jacobson PA, et al. Exposure-response relationships for oxaliplatin-treated colon cancer cells. Anti-cancer drugs. 2008;19 (1):37-44.
  38. da Silva RG, Sugarbaker PH. Analysis of prognostic factors in seventy patients having a complete cytoreduction plus perioperative intraperitoneal chemotherapy for carcinomatosis from colorectal cancer. Journal of the American College of Surgeons. 2006;203 (6):878-86.
  39. Prabhu A, Brandl A, Wakama S, Sako S, Ishibashi H, Mizumoto A, et al. Retrospective Analysis of Patients with Signet Ring Subtype of Colorectal Cancer with Peritoneal Metastasis Treated with CRS & HIPEC. Cancers. 2020;12 (9).
  40. Elias D, Gilly F, Boutitie F, Quenet F, Bereder JM, Mansvelt B, et al. Peritoneal colorectal carcinomatosis treated with surgery and perioperative intraperitoneal chemotherapy: retrospective analysis of 523 patients from a multicentric French study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2010;28 (1):63-8.
  41. Glehen O, Gilly FN, Boutitie F, Bereder JM, Quenet F, Sideris L, et al. Toward curative treatment of peritoneal carcinomatosis from nonovarian origin by cytoreductive surgery combined with perioperative intraperitoneal chemotherapy: a multi-institutional study of 1,290 patients. Cancer. 2010;116 (24):5608-18.
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تعداد مشاهده مقاله: 111
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