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Derakhshan, Zahra, Bahmanpour, Soghra, Alaee, Sanaz, Fallahi, Jafar, Tabei, Seyed Mohammad Bagher. (1402). The Role of Circular RNAs in Male Infertility and Reproductive Cancers: A Narrative Review. سامانه مدیریت نشریات علمی, 48(6), 527-541. doi: 10.30476/ijms.2022.95302.2661
Zahra Derakhshan; Soghra Bahmanpour; Sanaz Alaee; Jafar Fallahi; Seyed Mohammad Bagher Tabei. "The Role of Circular RNAs in Male Infertility and Reproductive Cancers: A Narrative Review". سامانه مدیریت نشریات علمی, 48, 6, 1402, 527-541. doi: 10.30476/ijms.2022.95302.2661
Derakhshan, Zahra, Bahmanpour, Soghra, Alaee, Sanaz, Fallahi, Jafar, Tabei, Seyed Mohammad Bagher. (1402). 'The Role of Circular RNAs in Male Infertility and Reproductive Cancers: A Narrative Review', سامانه مدیریت نشریات علمی, 48(6), pp. 527-541. doi: 10.30476/ijms.2022.95302.2661
Derakhshan, Zahra, Bahmanpour, Soghra, Alaee, Sanaz, Fallahi, Jafar, Tabei, Seyed Mohammad Bagher. The Role of Circular RNAs in Male Infertility and Reproductive Cancers: A Narrative Review. سامانه مدیریت نشریات علمی, 1402; 48(6): 527-541. doi: 10.30476/ijms.2022.95302.2661

The Role of Circular RNAs in Male Infertility and Reproductive Cancers: A Narrative Review

Iranian Journal of Medical Sciences
مقاله 2، دوره 48، شماره 6، بهمن و اسفند 2023، صفحه 527-541    اصل مقاله (1.47 M)
نوع مقاله: Review Article
شناسه دیجیتال (DOI): 10.30476/ijms.2022.95302.2661
نویسندگان
Zahra Derakhshan1؛ Soghra Bahmanpour2؛ Sanaz Alaee1، 3؛ Jafar Fallahi4؛ Seyed Mohammad Bagher Tabei* 5، 6
1Department of Reproductive Biology, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, Iran
2Department of Anatomy and Reproductive Biology, School of Medical Sciences, Shiraz University of Medical Sciences, Shiraz, Iran
3Stem Cells Technology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
4Department of Molecular Medicine, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, Iran
5Department of Medical Genetics, School of Medical Sciences, Shiraz University of Medical Sciences, Shiraz, Iran
6Maternal-Fetal Medicine Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
چکیده
Infertility is a global health problem affecting about 15% of all couples, of which 50% are due to male infertility. Although the etiology of infertility is known in most infertile men, idiopathic male infertility remains a challenge. Therefore, there is a need for novel diagnostic methods to detect the underlying mechanisms and develop appropriate therapies. Recent studies have focused on the role of non-coding RNAs (ncRNAs) in male infertility. Circular RNAs (CircRNAs), a type of ncRNAs, are found to play a key role in the development of some pathological conditions, including cardiovascular diseases, diabetes, cancers, autoimmune diseases, etc. Several studies have reported the presence of CircRNAs and their target genes in the human reproductive system. In addition, their expression in testicular tissues, sperm cells, and seminal fluid has been identified. Abnormal expression of CircRNAs has been associated with azoospermia and asthenozoospermia in infertile men. The present narrative review provides a brief description of the role of CircRNAs in spermatogenic cells, male infertility, and reproductive cancers. In addition, some CircRNAs have been identified as potential biomarkers for disease detection and treatment. 

تازه های تحقیق

Zahra Derakhshan (Google Scholar)

Seyed Mohammad Bagher Tabei (Google Scholar)

کلیدواژه‌ها
RNA؛ Circular؛ Infertility؛ Spermatozoa
سایر فایل های مرتبط با مقاله
مراجع
  1. Glazer CH, Eisenberg ML, Tottenborg SS, Giwercman A, Flachs EM, Brauner EV, et al. Male factor infertility and risk of death: a nationwide record-linkage study. Hum Reprod. 2019;34:2266-73. doi: 10.1093/humrep/dez189. PubMed PMID: 31725880.
  2. Panner Selvam MK, Ambar RF, Agarwal A, Henkel R. Etiologies of sperm DNA damage and its impact on male infertility. Andrologia. 2021;53:e13706. doi: 10.1111/and.13706. PubMed PMID: 32559347.
  3. Punjani N, Wald G, Al-Hussein Alwamlh O, Feliciano M, Dudley V, Goldstein M. Optimal timing for repeat semen analysis during male infertility evaluation. F S Rep. 2021;2:172-5. doi: 10.1016/j.xfre.2021.04.010. PubMed PMID: 34278350; PubMed Central PMCID: PMCPMC8267395.
  4. Babakhanzadeh E, Nazari M, Ghasemifar S, Khodadadian A. Some of the Factors Involved in Male Infertility: A Prospective Review. Int J Gen Med. 2020;13:29-41. doi: 10.2147/IJGM.S241099. PubMed PMID: 32104049; PubMed Central PMCID: PMCPMC7008178.
  5. Agarwal A, Parekh N, Panner Selvam MK, Henkel R, Shah R, Homa ST, et al. Male Oxidative Stress Infertility (MOSI): Proposed Terminology and Clinical Practice Guidelines for Management of Idiopathic Male Infertility. World J Mens Health. 2019;37:296-312. doi: 10.5534/wjmh.190055. PubMed PMID: 31081299; PubMed Central PMCID: PMCPMC6704307.
  6. Hamilton M, Russell S, Moskovtsev S, Krawetz SA, Librach C. The developmental significance of sperm-borne ribonucleic acids and their potential for use as diagnostic markers for male factor infertility. F&S Reviews. 2022;3:11-23. doi: 10.1016/j.xfnr.2021.11.005.
  7. Liu S, Lao Y, Wang Y, Li R, Fang X, Wang Y, et al. Role of RNA N6-Methyladenosine Modification in Male Infertility and Genital System Tumors. Front Cell Dev Biol. 2021;9:676364. doi: 10.3389/fcell.2021.676364. PubMed PMID: 34124065; PubMed Central PMCID: PMCPMC8190709.
  8. Zhang M, He P, Bian Z. Long Noncoding RNAs in Neurodegenerative Diseases: Pathogenesis and Potential Implications as Clinical Biomarkers. Front Mol Neurosci. 2021;14:685143. doi: 10.3389/fnmol.2021.685143. PubMed PMID: 34421536; PubMed Central PMCID: PMCPMC8371338.
  9. Watson CN, Belli A, Di Pietro V. Small Non-coding RNAs: New Class of Biomarkers and Potential Therapeutic Targets in Neurodegenerative Disease. Front Genet. 2019;10:364. doi: 10.3389/fgene.2019.00364. PubMed PMID: 31080456; PubMed Central PMCID: PMCPMC6497742.
  10. Robless EE, Howard JA, Casari I, Falasca M. Exosomal long non-coding RNAs in the diagnosis and oncogenesis of pancreatic cancer. Cancer Lett. 2021;501:55-65. doi: 10.1016/j.canlet.2020.12.005. PubMed PMID: 33359452.
  11. Mattick JS, Makunin IV. Non-coding RNA. Hum Mol Genet. 2006;15:R17-29. doi: 10.1093/hmg/ddl046. PubMed PMID: 16651366.
  12. Dong WW, Li HM, Qing XR, Huang DH, Li HG. Identification and characterization of human testis derived circular RNAs and their existence in seminal plasma. Sci Rep. 2016;6:39080. doi: 10.1038/srep39080. PubMed PMID: 27958373; PubMed Central PMCID: PMCPMC5153637.
  13. Cocquerelle C, Mascrez B, Hetuin D, Bailleul B. Mis-splicing yields circular RNA molecules. FASEB J. 1993;7:155-60. doi: 10.1096/fasebj.7.1.7678559. PubMed PMID: 7678559.
  14. Ebbesen KK, Hansen TB, Kjems J. Insights into circular RNA biology. RNA Biol. 2017;14:1035-45. doi: 10.1080/15476286.2016.1271524. PubMed PMID: 27982727; PubMed Central PMCID: PMCPMC5680708.
  15. Wu R, Li J, Li J, Yan X, Zhou W, Ling C, et al. Circular RNA expression profiling and bioinformatic analysis of cumulus cells in endometriosis infertility patients. Epigenomics. 2020;12:2093-108. doi: 10.2217/epi-2020-0291. PubMed PMID: 33090019.
  16. Kim E, Kim YK, Lee SV. Emerging functions of circular RNA in aging. Trends Genet. 2021;37:819-29. doi: 10.1016/j.tig.2021.04.014. PubMed PMID: 34016449.
  17. Vausort M, Salgado-Somoza A, Zhang L, Leszek P, Scholz M, Teren A, et al. Myocardial Infarction-Associated Circular RNA Predicting Left Ventricular Dysfunction. J Am Coll Cardiol. 2016;68:1247-8. doi: 10.1016/j.jacc.2016.06.040. PubMed PMID: 27609688.
  18. Wang K, Gan TY, Li N, Liu CY, Zhou LY, Gao JN, et al. Circular RNA mediates cardiomyocyte death via miRNA-dependent upregulation of MTP18 expression. Cell Death Differ. 2017;24:1111-20. doi: 10.1038/cdd.2017.61. PubMed PMID: 28498369; PubMed Central PMCID: PMCPMC5442477.
  19. Shan K, Liu C, Liu BH, Chen X, Dong R, Liu X, et al. Circular Noncoding RNA HIPK3 Mediates Retinal Vascular Dysfunction in Diabetes Mellitus. Circulation. 2017;136:1629-42. doi: 10.1161/CIRCULATIONAHA.117.029004. PubMed PMID: 28860123.
  20. Cardamone G, Paraboschi EM, Rimoldi V, Duga S, Solda G, Asselta R. The Characterization of GSDMB Splicing and Backsplicing Profiles Identifies Novel Isoforms and a Circular RNA That Are Dysregulated in Multiple Sclerosis. Int J Mol Sci. 2017;18. doi: 10.3390/ijms18030576. PubMed PMID: 28272342; PubMed Central PMCID: PMCPMC5372592.
  21. Guo JN, Li J, Zhu CL, Feng WT, Shao JX, Wan L, et al. Comprehensive profile of differentially expressed circular RNAs reveals that hsa_circ_0000069 is upregulated and promotes cell proliferation, migration, and invasion in colorectal cancer. Onco Targets Ther. 2016;9:7451-8. doi: 10.2147/OTT.S123220. PubMed PMID: 28003761; PubMed Central PMCID: PMCPMC5158168.
  22. Xu L, Zhang M, Zheng X, Yi P, Lan C, Xu M. The circular RNA ciRS-7 (Cdr1as) acts as a risk factor of hepatic microvascular invasion in hepatocellular carcinoma. J Cancer Res Clin Oncol. 2017;143:17-27. doi: 10.1007/s00432-016-2256-7. PubMed PMID: 27614453.
  23. Luo YH, Zhu XZ, Huang KW, Zhang Q, Fan YX, Yan PW, et al. Emerging roles of circular RNA hsa_circ_0000064 in the proliferation and metastasis of lung cancer. Biomed Pharmacother. 2017;96:892-8. doi: 10.1016/j.biopha.2017.12.015. PubMed PMID: 29223555.
  24. Zhao Y, Alexandrov PN, Jaber V, Lukiw WJ. Deficiency in the Ubiquitin Conjugating Enzyme UBE2A in Alzheimer’s Disease (AD) is Linked to Deficits in a Natural Circular miRNA-7 Sponge (circRNA; ciRS-7). Genes (Basel). 2016;7. doi: 10.3390/genes7120116. PubMed PMID: 27929395; PubMed Central PMCID: PMCPMC5192492.
  25. Panda AC, Grammatikakis I, Kim KM, De S, Martindale JL, Munk R, et al. Identification of senescence-associated circular RNAs (SAC-RNAs) reveals senescence suppressor CircPVT1. Nucleic Acids Res. 2017;45:4021-35. doi: 10.1093/nar/gkw1201. PubMed PMID: 27928058; PubMed Central PMCID: PMCPMC5397146.
  26. Qian Y, Lu Y, Rui C, Qian Y, Cai M, Jia R. Potential Significance of Circular RNA in Human Placental Tissue for Patients with Preeclampsia. Cell Physiol Biochem. 2016;39:1380-90. doi: 10.1159/000447842. PubMed PMID: 27606420.
  27. Cheng J, Huang J, Yuan S, Zhou S, Yan W, Shen W, et al. Circular RNA expression profiling of human granulosa cells during maternal aging reveals novel transcripts associated with assisted reproductive technology outcomes. PLoS One. 2017;12:e0177888. doi: 10.1371/journal.pone.0177888. PubMed PMID: 28644873; PubMed Central PMCID: PMCPMC5482436.
  28. Dang Y, Yan L, Hu B, Fan X, Ren Y, Li R, et al. Tracing the expression of circular RNAs in human pre-implantation embryos. Genome Biol. 2016;17:130. doi: 10.1186/s13059-016-0991-3. PubMed PMID: 27315811; PubMed Central PMCID: PMCPMC4911693.
  29. Kong Z, Wan X, Lu Y, Zhang Y, Huang Y, Xu Y, et al. Circular RNA circFOXO3 promotes prostate cancer progression through sponging miR-29a-3p. J Cell Mol Med. 2020;24:799-813. doi: 10.1111/jcmm.14791. PubMed PMID: 31733095; PubMed Central PMCID: PMCPMC6933405.
  30. Liu L, Li F, Wen Z, Li T, Lv M, Zhao X, et al. Preliminary investigation of the function of hsa_circ_0049356 in nonobstructive azoospermia patients. Andrologia. 2020;52:e13814. doi: 10.1111/and.13814. PubMed PMID: 32894622.
  31. Lv MQ, Zhou L, Ge P, Li YX, Zhang J, Zhou DX. Over-expression of hsa_circ_0000116 in patients with non-obstructive azoospermia and its predictive value in testicular sperm retrieval. Andrology. 2020;8:1834-43. doi: 10.1111/andr.12874. PubMed PMID: 32735753.
  32. Ji C, Wang Y, Wei X, Zhang X, Cong R, Yao L, et al. Potential of testis-derived circular RNAs in seminal plasma to predict the outcome of microdissection testicular sperm extraction in patients with idiopathic non-obstructive azoospermia. Hum Reprod. 2021;36:2649-60. doi: 10.1093/humrep/deab196. PubMed PMID: 34477868.
  33. Manfrevola F, Ferraro B, Sellitto C, Rocco D, Fasano S, Pierantoni R, et al. CRISP2, CATSPER1 and PATE1 Expression in Human Asthenozoospermic Semen. Cells. 2021;10. doi: 10.3390/cells10081956. PubMed PMID: 34440724; PubMed Central PMCID: PMCPMC8391270.
  34. Chen D, Lu X, Yang F, Xing N. Circular RNA circHIPK3 promotes cell proliferation and invasion of prostate cancer by sponging miR-193a-3p and regulating MCL1 expression. Cancer Manag Res. 2019;11:1415-23. doi: 10.2147/CMAR.S190669. PubMed PMID: 30863152; PubMed Central PMCID: PMCPMC6388976.
  35. Kong Z, Lu Y, Wan X, Luo J, Li D, Huang Y, et al. Comprehensive Characterization of Androgen-Responsive circRNAs in Prostate Cancer. Life (Basel). 2021;11. doi: 10.3390/life11101096. PubMed PMID: 34685466; PubMed Central PMCID: PMCPMC8538364.
  36. Jeck WR, Sorrentino JA, Wang K, Slevin MK, Burd CE, Liu J, et al. Circular RNAs are abundant, conserved, and associated with ALU repeats. RNA. 2013;19:141-57. doi: 10.1261/rna.035667.112. PubMed PMID: 23249747; PubMed Central PMCID: PMCPMC3543092.
  37. Zhang Y, Zhang XO, Chen T, Xiang JF, Yin QF, Xing YH, et al. Circular intronic long noncoding RNAs. Mol Cell. 2013;51:792-806. doi: 10.1016/j.molcel.2013.08.017. PubMed PMID: 24035497.
  38. Li Z, Huang C, Bao C, Chen L, Lin M, Wang X, et al. Exon-intron circular RNAs regulate transcription in the nucleus. Nat Struct Mol Biol. 2015;22:256-64. doi: 10.1038/nsmb.2959. PubMed PMID: 25664725.
  39. Zhang P, Chao Z, Zhang R, Ding R, Wang Y, Wu W, et al. Circular RNA Regulation of Myogenesis. Cells. 2019;8. doi: 10.3390/cells8080885. PubMed PMID: 31412632; PubMed Central PMCID: PMCPMC6721685.
  40. Lu M. Circular RNA: functions, applications and prospects. ExRNA. 2020;2:1-7. doi: 10.1186/s41544-019-0046-5.
  41. Chen LL, Yang L. Regulation of circRNA biogenesis. RNA Biol. 2015;12:381-8. doi: 10.1080/15476286.2015.1020271. PubMed PMID: 25746834; PubMed Central PMCID: PMCPMC4615371.
  42. Meng X, Li X, Zhang P, Wang J, Zhou Y, Chen M. Circular RNA: an emerging key player in RNA world. Brief Bioinform. 2017;18:547-57. doi: 10.1093/bib/bbw045. PubMed PMID: 27255916.
  43. Chen I, Chen CY, Chuang TJ. Biogenesis, identification, and function of exonic circular RNAs. Wiley Interdiscip Rev RNA. 2015;6:563-79. doi: 10.1002/wrna.1294. PubMed PMID: 26230526; PubMed Central PMCID: PMCPMC5042038.
  44. Ashwal-Fluss R, Meyer M, Pamudurti NR, Ivanov A, Bartok O, Hanan M, et al. circRNA biogenesis competes with pre-mRNA splicing. Mol Cell. 2014;56:55-66. doi: 10.1016/j.molcel.2014.08.019. PubMed PMID: 25242144.
  45. Huang A, Zheng H, Wu Z, Chen M, Huang Y. Circular RNA-protein interactions: functions, mechanisms, and identification. Theranostics. 2020;10:3503-17. doi: 10.7150/thno.42174. PubMed PMID: 32206104; PubMed Central PMCID: PMCPMC7069073.
  46. Starke S, Jost I, Rossbach O, Schneider T, Schreiner S, Hung LH, et al. Exon circularization requires canonical splice signals. Cell Rep. 2015;10:103-11. doi: 10.1016/j.celrep.2014.12.002. PubMed PMID: 25543144.
  47. Liang D, Tatomer DC, Luo Z, Wu H, Yang L, Chen LL, et al. The Output of Protein-Coding Genes Shifts to Circular RNAs When the Pre-mRNA Processing Machinery Is Limiting. Mol Cell. 2017;68:940-54 e3. doi: 10.1016/j.molcel.2017.10.034. PubMed PMID: 29174924; PubMed Central PMCID: PMCPMC5728686.
  48. Barrett SP, Wang PL, Salzman J. Circular RNA biogenesis can proceed through an exon-containing lariat precursor. Elife. 2015;4:e07540. doi: 10.7554/eLife.07540. PubMed PMID: 26057830; PubMed Central PMCID: PMCPMC4479058.
  49. Jeck WR, Sharpless NE. Detecting and characterizing circular RNAs. Nat Biotechnol. 2014;32:453-61. doi: 10.1038/nbt.2890. PubMed PMID: 24811520; PubMed Central PMCID: PMCPMC4121655.
  50. Bolha L, Ravnik-Glavac M, Glavac D. Circular RNAs: Biogenesis, Function, and a Role as Possible Cancer Biomarkers. Int J Genomics. 2017;2017:6218353. doi: 10.1155/2017/6218353. PubMed PMID: 29349062; PubMed Central PMCID: PMCPMC5733622.
  51. Li X, Liu CX, Xue W, Zhang Y, Jiang S, Yin QF, et al. Coordinated circRNA Biogenesis and Function with NF90/NF110 in Viral Infection. Mol Cell. 2017;67:214-27. doi: 10.1016/j.molcel.2017.05.023. PubMed PMID: 28625552.
  52. Errichelli L, Dini Modigliani S, Laneve P, Colantoni A, Legnini I, Capauto D, et al. FUS affects circular RNA expression in murine embryonic stem cell-derived motor neurons. Nat Commun. 2017;8:14741. doi: 10.1038/ncomms14741. PubMed PMID: 28358055; PubMed Central PMCID: PMCPMC5379105.
  53. Conn SJ, Pillman KA, Toubia J, Conn VM, Salmanidis M, Phillips CA, et al. The RNA binding protein quaking regulates formation of circRNAs. Cell. 2015;160:1125-34. doi: 10.1016/j.cell.2015.02.014. PubMed PMID: 25768908.
  54. Aktas T, Avsar Ilik I, Maticzka D, Bhardwaj V, Pessoa Rodrigues C, Mittler G, et al. DHX9 suppresses RNA processing defects originating from the Alu invasion of the human genome. Nature. 2017;544:115-9. doi: 10.1038/nature21715. PubMed PMID: 28355180.
  55. Knupp D, Cooper DA, Saito Y, Darnell RB, Miura P. NOVA2 regulates neural circRNA biogenesis. Nucleic Acids Res. 2021;49:6849-62. doi: 10.1093/nar/gkab523. PubMed PMID: 34157123; PubMed Central PMCID: PMCPMC8266653.
  56. Okholm TLH, Sathe S, Park SS, Kamstrup AB, Rasmussen AM, Shankar A, et al. Transcriptome-wide profiles of circular RNA and RNA-binding protein interactions reveal effects on circular RNA biogenesis and cancer pathway expression. Genome Med. 2020;12:112. doi: 10.1186/s13073-020-00812-8. PubMed PMID: 33287884; PubMed Central PMCID: PMCPMC7722315.
  57. Zhang XO, Wang HB, Zhang Y, Lu X, Chen LL, Yang L. Complementary sequence-mediated exon circularization. Cell. 2014;159:134-47. doi: 10.1016/j.cell.2014.09.001. PubMed PMID: 25242744.
  58. Weng W, Wei Q, Toden S, Yoshida K, Nagasaka T, Fujiwara T, et al. Circular RNA ciRS-7-A Promising Prognostic Biomarker and a Potential Therapeutic Target in Colorectal Cancer. Clin Cancer Res. 2017;23:3918-28. doi: 10.1158/1078-0432.CCR-16-2541. PubMed PMID: 28174233; PubMed Central PMCID: PMCPMC5511556.
  59. Du WW, Yang W, Liu E, Yang Z, Dhaliwal P, Yang BB. Foxo3 circular RNA retards cell cycle progression via forming ternary complexes with p21 and CDK2. Nucleic Acids Res. 2016;44:2846-58. doi: 10.1093/nar/gkw027. PubMed PMID: 26861625; PubMed Central PMCID: PMCPMC4824104.
  60. Legnini I, Di Timoteo G, Rossi F, Morlando M, Briganti F, Sthandier O, et al. Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis. Mol Cell. 2017;66:22-37. doi: 10.1016/j.molcel.2017.02.017. PubMed PMID: 28344082; PubMed Central PMCID: PMCPMC5387670.
  61. Das A, Gorospe M, Panda AC. The coding potential of circRNAs. Aging (Albany NY). 2018;10:2228-9. doi: 10.18632/aging.101554. PubMed PMID: 30215602; PubMed Central PMCID: PMCPMC6188482.
  62. Gao Y, Wu M, Fan Y, Li S, Lai Z, Huang Y, et al. Identification and characterization of circular RNAs in Qinchuan cattle testis. R Soc Open Sci. 2018;5:180413. doi: 10.1098/rsos.180413. PubMed PMID: 30109096; PubMed Central PMCID: PMCPMC6083711.
  63. de Kretser DM, Loveland KL, Meinhardt A, Simorangkir D, Wreford N. Spermatogenesis. Hum Reprod. 1998;13:1-8. doi: 10.1093/humrep/13.suppl_1.1. PubMed PMID: 9663765.
  64. Yu Z, Guo R, Ge Y, Ma J, Guan J, Li S, et al. Gene expression profiles in different stages of mouse spermatogenic cells during spermatogenesis. Biol Reprod. 2003;69:37-47. doi: 10.1095/biolreprod.102.012609. PubMed PMID: 12606389.
  65. Capel B, Swain A, Nicolis S, Hacker A, Walter M, Koopman P, et al. Circular transcripts of the testis-determining gene Sry in adult mouse testis. Cell. 1993;73:1019-30. doi: 10.1016/0092-8674(93)90279-y. PubMed PMID: 7684656.
  66. Hansen TB, Jensen TI, Clausen BH, Bramsen JB, Finsen B, Damgaard CK, et al. Natural RNA circles function as efficient microRNA sponges. Nature. 2013;495:384-8. doi: 10.1038/nature11993. PubMed PMID: 23446346.
  67. Li T, Luo R, Wang X, Wang H, Zhao X, Guo Y, et al. Unraveling Stage-Dependent Expression Patterns of Circular RNAs and Their Related ceRNA Modulation in Ovine Postnatal Testis Development. Front Cell Dev Biol. 2021;9:627439. doi: 10.3389/fcell.2021.627439. PubMed PMID: 33816472; PubMed Central PMCID: PMCPMC8017185.
  68. Zhou T, Xie X, Li M, Shi J, Zhou JJ, Knox KS, et al. Rat BodyMap transcriptomes reveal unique circular RNA features across tissue types and developmental stages. RNA. 2018;24:1443-56. doi: 10.1261/rna.067132.118. PubMed PMID: 30093490; PubMed Central PMCID: PMCPMC6191709.
  69. You X, Vlatkovic I, Babic A, Will T, Epstein I, Tushev G, et al. Neural circular RNAs are derived from synaptic genes and regulated by development and plasticity. Nat Neurosci. 2015;18:603-10. doi: 10.1038/nn.3975. PubMed PMID: 25714049; PubMed Central PMCID: PMCPMC4376664.
  70. Zhang F, Zhang X, Ning W, Zhang X, Ru Z, Wang S, et al. Expression Analysis of Circular RNAs in Young and Sexually Mature Boar Testes. Animals (Basel). 2021;11. doi: 10.3390/ani11051430. PubMed PMID: 34067577; PubMed Central PMCID: PMCPMC8156704.
  71. Legrand JMD, Chan AL, La HM, Rossello FJ, Anko ML, Fuller-Pace FV, et al. DDX5 plays essential transcriptional and post-transcriptional roles in the maintenance and function of spermatogonia. Nat Commun. 2019;10:2278. doi: 10.1038/s41467-019-09972-7. PubMed PMID: 31123254; PubMed Central PMCID: PMCPMC6533336.
  72. Zhou F, Chen W, Jiang Y, He Z. Regulation of long non-coding RNAs and circular RNAs in spermatogonial stem cells. Reproduction. 2019;158:R15-R25. doi: 10.1530/REP-18-0517. PubMed PMID: 30939448.
  73. Lin X, Han M, Cheng L, Chen J, Zhang Z, Shen T, et al. Expression dynamics, relationships, and transcriptional regulations of diverse transcripts in mouse spermatogenic cells. RNA Biol. 2016;13:1011-24. doi: 10.1080/15476286.2016.1218588. PubMed PMID: 27560004; PubMed Central PMCID: PMCPMC5056783.
  74. Tang C, Xie Y, Yu T, Liu N, Wang Z, Woolsey RJ, et al. m(6)A-dependent biogenesis of circular RNAs in male germ cells. Cell Res. 2020;30:211-28. doi: 10.1038/s41422-020-0279-8. PubMed PMID: 32047269; PubMed Central PMCID: PMCPMC7054367.
  75. Chioccarelli T, Manfrevola F, Ferraro B, Sellitto C, Cobellis G, Migliaccio M, et al. Expression Patterns of Circular RNAs in High Quality and Poor Quality Human Spermatozoa. Front Endocrinol (Lausanne). 2019;10:435. doi: 10.3389/fendo.2019.00435. PubMed PMID: 31338066; PubMed Central PMCID: PMCPMC6626923.
  76. Godia M, Castello A, Rocco M, Cabrera B, Rodriguez-Gil JE, Balasch S, et al. Identification of circular RNAs in porcine sperm and evaluation of their relation to sperm motility. Sci Rep. 2020;10:7985. doi: 10.1038/s41598-020-64711-z. PubMed PMID: 32409652; PubMed Central PMCID: PMCPMC7224279.
  77. Chioccarelli T, Falco G, Cappetta D, De Angelis A, Roberto L, Addeo M, et al. FUS driven circCNOT6L biogenesis in mouse and human spermatozoa supports zygote development. Cell Mol Life Sci. 2021;79:50. doi: 10.1007/s00018-021-04054-8. PubMed PMID: 34936029; PubMed Central PMCID: PMCPMC8739325.
  78. Guo L, Chao SB, Xiao L, Wang ZB, Meng TG, Li YY, et al. Sperm-carried RNAs play critical roles in mouse embryonic development. Oncotarget. 2017;8:67394-405. doi: 10.18632/oncotarget.18672. PubMed PMID: 28978041; PubMed Central PMCID: PMCPMC5620181.
  79. Ragusa M, Barbagallo D, Chioccarelli T, Manfrevola F, Cobellis G, Di Pietro C, et al. CircNAPEPLD is expressed in human and murine spermatozoa and physically interacts with oocyte miRNAs. RNA Biol. 2019;16:1237-48. doi: 10.1080/15476286.2019.1624469. PubMed PMID: 31135264; PubMed Central PMCID: PMCPMC6693540.
  80. Caroppo E, Colpi GM. Update on the Management of Non-Obstructive Azoospermia: Current Evidence and Unmet Needs. J Clin Med. 2021;11. doi: 10.3390/jcm11010062. PubMed PMID: 35011799; PubMed Central PMCID: PMCPMC8745473.
  81. Arafat M, Har-Vardi I, Harlev A, Levitas E, Zeadna A, Abofoul-Azab M, et al. Mutation in TDRD9 causes non-obstructive azoospermia in infertile men. J Med Genet. 2017;54:633-9. doi: 10.1136/jmedgenet-2017-104514. PubMed PMID: 28536242.
  82. Oka S, Shiraishi K, Matsuyama H. Effects of human chorionic gonadotropin on testicular interstitial tissues in men with non-obstructive azoospermia. Andrology. 2017;5:232-9. doi: 10.1111/andr.12292. PubMed PMID: 27860441.
  83. Abdel Raheem A, Garaffa G, Rushwan N, De Luca F, Zacharakis E, Abdel Raheem T, et al. Testicular histopathology as a predictor of a positive sperm retrieval in men with non-obstructive azoospermia. BJU Int. 2013;111:492-9. doi: 10.1111/j.1464-410X.2012.11203.x. PubMed PMID: 22583840.
  84. Tsujimura A, Matsumiya K, Miyagawa Y, Takao T, Fujita K, Koga M, et al. Prediction of successful outcome of microdissection testicular sperm extraction in men with idiopathic nonobstructive azoospermia. J Urol. 2004;172:1944-7. doi: 10.1097/01.ju.0000142885.20116.60. PubMed PMID: 15540761.
  85. Yao JT, Zhao SH, Liu QP, Lv MQ, Zhou DX, Liao ZJ, et al. Over-expression of CircRNA_100876 in non-small cell lung cancer and its prognostic value. Pathol Res Pract. 2017;213:453-6. doi: 10.1016/j.prp.2017.02.011. PubMed PMID: 28343871.
  86. Li P, Chen S, Chen H, Mo X, Li T, Shao Y, et al. Using circular RNA as a novel type of biomarker in the screening of gastric cancer. Clin Chim Acta. 2015;444:132-6. doi: 10.1016/j.cca.2015.02.018. PubMed PMID: 25689795.
  87. Ge P, Zhang J, Zhou L, Lv MQ, Li YX, Wang J, et al. CircRNA expression profile and functional analysis in testicular tissue of patients with non-obstructive azoospermia. Reprod Biol Endocrinol. 2019;17:100. doi: 10.1186/s12958-019-0541-4. PubMed PMID: 31775841; PubMed Central PMCID: PMCPMC6880412.
  88. Bo H, Liu Z, Tang R, Gong G, Wang X, Zhang H, et al. Testicular biopsies microarray analysis reveals circRNAs are involved in the pathogenesis of non-obstructive azoospermia. Aging (Albany NY). 2020;12:2610-25. doi: 10.18632/aging.102765. PubMed PMID: 32029690; PubMed Central PMCID: PMCPMC7041731.
  89. Zhu F, Luo Y, Bo H, Gong G, Tang R, Fan J, et al. Trace the profile and function of circular RNAs in Sertoli cell only syndrome. Genomics. 2021;113:1845-54. doi: 10.1016/j.ygeno.2021.04.022. PubMed PMID: 33865957.
  90. Zhou Y, Yao W, Zhang D, Yu Y, Chen S, Lu H, et al. Effectiveness of acupuncture for asthenozoospermia: A protocol for systematic review and meta-analysis. Medicine (Baltimore). 2021;100:e25711. doi: 10.1097/MD.0000000000025711. PubMed PMID: 33907155; PubMed Central PMCID: PMCPMC8084068.
  91. Tang D, Sha Y, Gao Y, Zhang J, Cheng H, Zhang J, et al. Novel variants in DNAH9 lead to nonsyndromic severe asthenozoospermia. Reprod Biol Endocrinol. 2021;19:27. doi: 10.1186/s12958-021-00709-0. PubMed PMID: 33610189; PubMed Central PMCID: PMCPMC7896388.
  92. Zhao K, Zhang J, Xu Z, Xu Y, Xu A, Chen W, et al. Metabolomic Profiling of Human Spermatozoa in Idiopathic Asthenozoospermia Patients Using Gas Chromatography-Mass Spectrometry. Biomed Res Int. 2018;2018:8327506. doi: 10.1155/2018/8327506. PubMed PMID: 29682560; PubMed Central PMCID: PMCPMC5851030.
  93. Kang H, Chen C, Gao F-X, Zeng X-H, Zhang X-N. Expression of PPP3CC and not PPP3R2 is associated with asthenozoospermia. Journal of Men’s Health. 2021;17:183-9. doi: 10.31083/jomh.2021.039.
  94. Mazaheri Moghaddam M, Mazaheri Moghaddam M, Amini M, Bahramzadeh B, Baghbanzadeh A, Biglari A, et al. Evaluation of SEPT2 and SEPT4 transcript contents in spermatozoa from men with asthenozoospermia and teratozoospermia. Health Sci Rep. 2021;4:e436. doi: 10.1002/hsr2.436. PubMed PMID: 34849407; PubMed Central PMCID: PMCPMC8611181.
  95. Gao L, Chang S, Xia W, Wang X, Zhang C, Cheng L, et al. Circular RNAs from BOULE play conserved roles in protection against stress-induced fertility decline. Sci Adv. 2020;6. doi: 10.1126/sciadv.abb7426. PubMed PMID: 33177084; PubMed Central PMCID: PMCPMC7673749.
  96. Dong Y, He D, Peng Z, Peng W, Shi W, Wang J, et al. Circular RNAs in cancer: an emerging key player. J Hematol Oncol. 2017;10:2. doi: 10.1186/s13045-016-0370-2. PubMed PMID: 28049499; PubMed Central PMCID: PMCPMC5210264.
  97. Wang F, Nazarali AJ, Ji S. Circular RNAs as potential biomarkers for cancer diagnosis and therapy. Am J Cancer Res. 2016;6:1167-76. PubMed PMID: 27429839; PubMed Central PMCID: PMCPMC4937728.
  98. Cai H, Zhang P, Xu M, Yan L, Liu N, Wu X. Circular RNA hsa_circ_0000263 participates in cervical cancer development by regulating target gene of miR-150-5p. J Cell Physiol. 2019;234:11391-400. doi: 10.1002/jcp.27796. PubMed PMID: 30569515.
  99. Ahmed I, Karedath T, Andrews SS, Al-Azwani IK, Mohamoud YA, Querleu D, et al. Altered expression pattern of circular RNAs in primary and metastatic sites of epithelial ovarian carcinoma. Oncotarget. 2016;7:36366-81. doi: 10.18632/oncotarget.8917. PubMed PMID: 27119352; PubMed Central PMCID: PMCPMC5095006.
  100. Passos GR, Ghezzi AC, Antunes E, de Oliveira MG, Monica FZ. The Role of Periprostatic Adipose Tissue on Prostate Function in Vascular-Related Disorders. Front Pharmacol. 2021;12:626155. doi: 10.3389/fphar.2021.626155. PubMed PMID: 33643052; PubMed Central PMCID: PMCPMC7908035.
  101. Verze P, Cai T, Lorenzetti S. The role of the prostate in male fertility, health and disease. Nat Rev Urol. 2016;13:379-86. doi: 10.1038/nrurol.2016.89. PubMed PMID: 27245504.
  102. Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, et al. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin. 2021;71:209-49. doi: 10.3322/caac.21660. PubMed PMID: 33538338.
  103. Xia Q, Ding T, Zhang G, Li Z, Zeng L, Zhu Y, et al. Circular RNA Expression Profiling Identifies Prostate Cancer- Specific circRNAs in Prostate Cancer. Cell Physiol Biochem. 2018;50:1903-15. doi: 10.1159/000494870. PubMed PMID: 30396163.
  104. Ge S, Sun C, Hu Q, Guo Y, Xia G, Mi Y, et al. Differential expression profiles of circRNAs in human prostate cancer based on chip and bioinformatic analysis. Int J Clin Exp Pathol. 2020;13:1045-52. PubMed PMID: 32509077; PubMed Central PMCID: PMCPMC7270690.
  105. Wu YP, Lin XD, Chen SH, Ke ZB, Lin F, Chen DN, et al. Identification of Prostate Cancer-Related Circular RNA Through Bioinformatics Analysis. Front Genet. 2020;11:892. doi: 10.3389/fgene.2020.00892. PubMed PMID: 32922436; PubMed Central PMCID: PMCPMC7457069.
  106. Wang Y, Liu B. Circular RNA in Diseased Heart. Cells. 2020;9. doi: 10.3390/cells9051240. PubMed PMID: 32429565; PubMed Central PMCID: PMCPMC7290921.
  107. Hansen EB, Fredsoe J, Okholm TLH, Ulhoi BP, Klingenberg S, Jensen JB, et al. The transcriptional landscape and biomarker potential of circular RNAs in prostate cancer. Genome Med. 2022;14:8. doi: 10.1186/s13073-021-01009-3. PubMed PMID: 35078526; PubMed Central PMCID: PMCPMC8788096.
  108. Lin Q, Cai J, Wang QQ. The Significance of Circular RNA DDX17 in Prostate Cancer. Biomed Res Int. 2020;2020:1878431. doi: 10.1155/2020/1878431. PubMed PMID: 32904557; PubMed Central PMCID: PMCPMC7456467.
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