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Tangarpoor, Maryam, Khademi, Bijan, Mardani, Maryam, Malekzadeh, Mahyar, Jaafari-Ashkavandi, Zohreh. (1402). Vitamin D Serum Levels in Oral Lichen Planus and Oral Cancer Patients. سامانه مدیریت نشریات علمی, 14(4), 530-536. doi: 10.30476/mejc.2023.95276.1762
Maryam Tangarpoor; Bijan Khademi; Maryam Mardani; Mahyar Malekzadeh; Zohreh Jaafari-Ashkavandi. "Vitamin D Serum Levels in Oral Lichen Planus and Oral Cancer Patients". سامانه مدیریت نشریات علمی, 14, 4, 1402, 530-536. doi: 10.30476/mejc.2023.95276.1762
Tangarpoor, Maryam, Khademi, Bijan, Mardani, Maryam, Malekzadeh, Mahyar, Jaafari-Ashkavandi, Zohreh. (1402). 'Vitamin D Serum Levels in Oral Lichen Planus and Oral Cancer Patients', سامانه مدیریت نشریات علمی, 14(4), pp. 530-536. doi: 10.30476/mejc.2023.95276.1762
Tangarpoor, Maryam, Khademi, Bijan, Mardani, Maryam, Malekzadeh, Mahyar, Jaafari-Ashkavandi, Zohreh. Vitamin D Serum Levels in Oral Lichen Planus and Oral Cancer Patients. سامانه مدیریت نشریات علمی, 1402; 14(4): 530-536. doi: 10.30476/mejc.2023.95276.1762

Vitamin D Serum Levels in Oral Lichen Planus and Oral Cancer Patients

Middle East Journal of Cancer
مقاله 6، دوره 14، شماره 4 - شماره پیاپی 56، دی 2023، صفحه 530-536    اصل مقاله (100.48 K)
نوع مقاله: Original Article(s)
شناسه دیجیتال (DOI): 10.30476/mejc.2023.95276.1762
نویسندگان
Maryam Tangarpoor1؛ Bijan Khademi2؛ Maryam Mardani3؛ Mahyar Malekzadeh4؛ Zohreh Jaafari-Ashkavandi* 1
1Department of Oral and Maxillofacial Pathology, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran
2Otolaryngology Research Center, Department of Otolaryngology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
3Department of Oral Medicine, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran
4Shiraz Institute for Cancer Research, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
چکیده
Background: This study aimed to evaluate serum vitamin D levels in patients with oral lichen planus (OLP) and oral squamous cell carcinoma (OSCC) in comparison to healthy controls in an Iranian population.
Method: A cross-sectional study was conducted, which included 69 patients with OLP, 40 patients with OSCC, and 60 healthy controls. Serum vitamin D levels were measured using the ELISA method. The data were analyzed using Mann-Whitney and T-tests, and statistical significance was set at P < 0.05.
Results: The study found that 17.9% of OLP patients, 27.25% of OSCC patients, and 25% of the control group had normal vitamin D levels. The mean vitamin D level in OLP patients (17.00 ± 14.16 ng/mL) was significantly lower than that in the control group (22.99 ± 14.46 ng/mL) (P = 0.003). However, in OSCC patients, the mean vitamin D level (24.63 ± 16.19 ng/mL) was not significantly different from that of the control group.
Conclusion: The study revealed a high rate of vitamin D deficiency and insufficiency in OLP, OSCC, and control group patients. Vitamin D deficiency was more common in patients with OLP. Vitamin D deficiency may potentially increase the risk of OLP and OSCC development and progression.

تازه های تحقیق

Zohreh Jaafari-Ashkavandi (Google Scholar)

کلیدواژه‌ها
Neoplasms؛ Lichen Planus؛ Oral؛ Vitamin D؛ Serum
مراجع
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