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Dehghanpisheh, Laleh, Sahmeddini, Mohammad Ali, Kaboodkhani, Reza, Samadi, Kazem, Khademi, Saeed, Rafati, Zahra, Abbasi, Sanaz, Abbasi, Razieh. (1402). Efficacy of Isoflurane-Remifentanil versus Propofol-Remifentanil on Controlled Hypotension and Surgeon Satisfaction in Rhinoplasty: A Single-Blind Clinical Trial Study. سامانه مدیریت نشریات علمی, 48(4), 379-384. doi: 10.30476/ijms.2022.94781.2608
Laleh Dehghanpisheh; Mohammad Ali Sahmeddini; Reza Kaboodkhani; Kazem Samadi; Saeed Khademi; Zahra Rafati; Sanaz Abbasi; Razieh Abbasi. "Efficacy of Isoflurane-Remifentanil versus Propofol-Remifentanil on Controlled Hypotension and Surgeon Satisfaction in Rhinoplasty: A Single-Blind Clinical Trial Study". سامانه مدیریت نشریات علمی, 48, 4, 1402, 379-384. doi: 10.30476/ijms.2022.94781.2608
Dehghanpisheh, Laleh, Sahmeddini, Mohammad Ali, Kaboodkhani, Reza, Samadi, Kazem, Khademi, Saeed, Rafati, Zahra, Abbasi, Sanaz, Abbasi, Razieh. (1402). 'Efficacy of Isoflurane-Remifentanil versus Propofol-Remifentanil on Controlled Hypotension and Surgeon Satisfaction in Rhinoplasty: A Single-Blind Clinical Trial Study', سامانه مدیریت نشریات علمی, 48(4), pp. 379-384. doi: 10.30476/ijms.2022.94781.2608
Dehghanpisheh, Laleh, Sahmeddini, Mohammad Ali, Kaboodkhani, Reza, Samadi, Kazem, Khademi, Saeed, Rafati, Zahra, Abbasi, Sanaz, Abbasi, Razieh. Efficacy of Isoflurane-Remifentanil versus Propofol-Remifentanil on Controlled Hypotension and Surgeon Satisfaction in Rhinoplasty: A Single-Blind Clinical Trial Study. سامانه مدیریت نشریات علمی, 1402; 48(4): 379-384. doi: 10.30476/ijms.2022.94781.2608

Efficacy of Isoflurane-Remifentanil versus Propofol-Remifentanil on Controlled Hypotension and Surgeon Satisfaction in Rhinoplasty: A Single-Blind Clinical Trial Study

Iranian Journal of Medical Sciences
مقاله 4، دوره 48، شماره 4، مهر 2023، صفحه 379-384    اصل مقاله (764.48 K)
نوع مقاله: Original Article(s)
شناسه دیجیتال (DOI): 10.30476/ijms.2022.94781.2608
نویسندگان
Laleh Dehghanpisheh1؛ Mohammad Ali Sahmeddini1؛ Reza Kaboodkhani2؛ Kazem Samadi3؛ Saeed Khademi1؛ Zahra Rafati1؛ Sanaz Abbasi1؛ Razieh Abbasi* 1
1Anesthesiology and Critical Care Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
2Otolaryngology Research Center, Department of Otorhinolaryngology, Shiraz University of Medical Sciences, Shiraz, Iran
3Department of Anesthesiology, Shahid Dastgheib Hospital, Shiraz University of Medical Sciences, Shiraz, Iran
چکیده
Background: Rhinoplasty is a complex but popular surgery in Iran. The main complications of the surgery are post-operative bleeding and nasal septal hematoma due to poor intra-operative controlled hypertension. This study aimed to compare the efficacy of isoflurane-remifentanil (I-R) versus propofol-remifentanil (P-R) to induce controlled hypotension and to assess surgeon satisfaction with each of these combinations during rhinoplasty. 
Methods: In 2020-2021, a single-blind clinical study was conducted on 98 patients aged 18-50 years undergoing rhinoplasty at Mother and Child Hospital (Shiraz, Iran). Patients were randomly divided into P-R (n=48) and I-R (n=50) groups. Changes in systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), and heart rate (HR) were assessed during surgery and in the recovery room. A questionnaire was used to evaluate the level of surgeon satisfaction. Data were analyzed using independent samples t test, Chi-square test, and repeated measures ANOVA with SPSS software. P<0.05 was considered statistically significant.
Results: Five minutes after anesthesia induction, the P-R combination had a greater effect on reducing SBP (P=0.010), DBP (P=0.007), MAP (P=0.003), and HR (P=0.026) than I-R. However, from the 40th minute to the end of surgery and after 30 minutes of recovery, the I-R combination had a slightly better effect on blood pressure reduction than P-R. There was no difference in surgeon satisfaction with either of the two drug combinations.
Conclusion: Both P-R and I-R combinations are recommended to induce hypotension during rhinoplasty. However, I-R is more effective than P-R in inducing the desired controlled hypotension. 
کلیدواژه‌ها
Hypotension؛ Propofol؛ Isoflurane؛ Rhinoplasty؛ Remifentanil
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مراجع
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