Maternal Cold-Reacting Immunoglobulin G Anti-M of MNS Blood Group System Causing Hemolytic Disease of the Fetus | ||
| Iranian Journal of Immunology | ||
| دوره 20، شماره 1، بهار 2023، صفحه 129-134 اصل مقاله (586.71 K) | ||
| نوع مقاله: Case Report | ||
| شناسه دیجیتال (DOI): 10.22034/iji.2023.93993.2273 | ||
| نویسندگان | ||
| Yan-Lian Liang1؛ Yu Shi2؛ Yu-Qing Su1؛ Fan Wu1؛ Yanwen Liang3؛ Xiuchu Fan3؛ Jiansuo Lin3؛ Yi Liu4؛ Long Peng1؛ Jianwei Ren5؛ Shuang Liang* 1 | ||
| 1Shenzhen Institute of Transfusion Medicine, Shenzhen Blood Center, Shenzhen, Guangdong, China. | ||
| 2Department of Biomedical Sciences, City University of Hong Kong, Hong Kong SAR, China. | ||
| 3R&D Division, Shenzhen Ritzcon Biological Technology Co., Ltd., Shenzhen, Guangdong, P.R.China. | ||
| 4Guangdong Key Laboratory for Research and Development of Natural Drugs, Department of Pharmacology, Marine Medicine Research Institute, Guangdong Medical University, Zhanjiang, Guangdong, P.R.China. | ||
| 5Department of Biomedical Sciences, City University of Hong Kong, Hong Kong SAR, China. R&D Division, Shenzhen Ritzcon Biological Technology Co., Ltd., Shenzhen, Guangdong, P.R.China. Centre for Regenerative Medicine and Health, Hong Kong Institute of Science & Innovation, Chinese Academy of Sciences, Hong Kong SAR, P.R.China. | ||
| چکیده | ||
| Several cases of the hemolytic disease of the fetus and newborn (HDFN) caused by immunoglobulin G (IgG) anti-M antibodies have been reported, in which almost all the HDFN-associated anti-M were warmly reacting. Here we report two cases of severe HDFN associated with cold-reacting IgG anti-M. In both cases, pregnancy was terminated, in weeks 33 and 23 respectively, due to a diagnosis of fetal growth retardation (FGR). To our knowledge, these are the most severe HDFN cases caused by cold-reacting IgG anti-M. | ||
| کلیدواژهها | ||
| Anti-M Antibody؛ Cold-reacting IgG؛ HDFN؛ MNS Blood Group | ||
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