LinkedIn

آمار

تعداد نشریات20
تعداد شماره‌ها995
تعداد مقالات9,123
تعداد مشاهده مقاله10,670,167
تعداد دریافت فایل اصل مقاله5,133,029
Bagheri, Maryam, Azizian, Saleh, Veisani, Yousef, Mikaili, Yasser, Salari, Sajjad. (1401). Association of Serum Vitamin D Levels with the Risk of Suicidal Behavior in Ilam, Iran: A Brief Report. سامانه مدیریت نشریات علمی, (), -. doi: 10.30476/ijms.2022.94422.2568
Maryam Bagheri; Saleh Azizian; Yousef Veisani; Yasser Mikaili; Sajjad Salari. "Association of Serum Vitamin D Levels with the Risk of Suicidal Behavior in Ilam, Iran: A Brief Report". سامانه مدیریت نشریات علمی, , , 1401, -. doi: 10.30476/ijms.2022.94422.2568
Bagheri, Maryam, Azizian, Saleh, Veisani, Yousef, Mikaili, Yasser, Salari, Sajjad. (1401). 'Association of Serum Vitamin D Levels with the Risk of Suicidal Behavior in Ilam, Iran: A Brief Report', سامانه مدیریت نشریات علمی, (), pp. -. doi: 10.30476/ijms.2022.94422.2568
Bagheri, Maryam, Azizian, Saleh, Veisani, Yousef, Mikaili, Yasser, Salari, Sajjad. Association of Serum Vitamin D Levels with the Risk of Suicidal Behavior in Ilam, Iran: A Brief Report. سامانه مدیریت نشریات علمی, 1401; (): -. doi: 10.30476/ijms.2022.94422.2568

Association of Serum Vitamin D Levels with the Risk of Suicidal Behavior in Ilam, Iran: A Brief Report

Iranian Journal of Medical Sciences
مقالات آماده انتشار، اصلاح شده برای چاپ، انتشار آنلاین از تاریخ 11 بهمن 1401  XML اصل مقاله (315.23 K)
نوع مقاله: Brief Report(s)
شناسه دیجیتال (DOI): 10.30476/ijms.2022.94422.2568
نویسندگان
Maryam Bagheriorcid 1؛ Saleh Azizian2؛ Yousef Veisani3؛ Yasser Mikaili4؛ Sajjad Salari email orcid 1
1Department of Physiology, School of Medicine, Ilam University of Medical Sciences, Ilam, Iran
2Department of Pathology, Cancer Institute, Tehran University of Medical Sciences, Tehan, Iran
3Non-Communicable Diseases Research Center, Ilam University of Medical Sciences, Ilam, Iran
4School of Medicine, Ilam University of Medical Sciences, Ilam, Iran
چکیده
There are conflicting reports on the effect of serum vitamin D (VD) levels on the development of suicidal behavior. VD deficiency is prevalent in Ilam province, and this region has the highest suicide mortality rate in Iran. The present study aimed to evaluate a possible association between serum VD levels and the risk of suicide among the inhabitants of Ilam province. A total of 157 suicide attempters (case group) and 314 age- and sex-matched individuals (control group) without a history of suicide attempts were recruited into the study. Suicide attempters were admitted to the Emergency Department of Ilam Shahid Mostafa Khomeini Hospital (Ilam, Iran) between March 2018 and March 2019. The individuals in the control group were randomly selected from those referred to various medical laboratories in Ilam during the same period. The participants in both groups were aged 18-35 years, and none had a history of kidney, liver, or endocrine diseases. Serum VD levels were measured using the enzyme-linked immunosorbent assay method. Categorical and continuous variables were compared using the Chi square test and independent samples t test, respectively. Serum VD level in the control group (31.5±0.2 ng/mL) was significantly lower than in the case group (43.1±0.1 ng/mL) (P<0.001). The results of logistic regression analysis showed that an increase in serum VD score was associated with an increase in the likelihood of suicide attempts (OR=1.05, 95% CI=1.03-1.06, P<0.001). Our findings confirmed the role of VD deficiency in the development of suicidal behavior. However, it is not a significant factor in its pathogenesis.
کلیدواژه‌ها
Suicide؛ Attempted؛ Vitamin D deficiency؛ Iran
مراجع
  1. Organization WH. Mental Health–Prevention of Suicidal Behaviours: A Task For All. Geneva, Switzerland: WHO; 2016. 
  2. Oshnokhah M, Bagheri M, Ghaneialvar H, Haghani K, Khorshidi A, Shahbazi A, et al. The Role of Oxidant-Antioxidant Status in Suicide Behavior in Kurdish Ethnicity. Basic Clin Neurosci. 2021;12:667-74. doi: 10.32598/bcn.2021.1917.1. PubMed PMID: 35173920; PubMed Central PMCID: PMCPMC8818118.
  3. Turecki G, Brent DA, Gunnell D, O’Connor RC, Oquendo MA, Pirkis J, et al. Suicide and suicide risk. Nat Rev Dis Primers. 2019;5:74. doi: 10.1038/s41572-019-0121-0. PubMed PMID: 31649257.
  4. Postolache TT, Mortensen PB, Tonelli LH, Jiao X, Frangakis C, Soriano JJ, et al. Seasonal spring peaks of suicide in victims with and without prior history of hospitalization for mood disorders. J Affect Disord. 2010;121:88-93. doi: 10.1016/j.jad.2009.05.015. PubMed PMID: 19535151; PubMed Central PMCID: PMCPMC2837087.
  5. Eyles DW, Feron F, Cui X, Kesby JP, Harms LH, Ko P, et al. Developmental vitamin D deficiency causes abnormal brain development. Psychoneuroendocrinology. 2009;34:S247-57. doi: 10.1016/j.psyneuen.2009.04.015. PubMed PMID: 19500914.
  6. Belzeaux R, Boyer L, Ibrahim EC, Feron F, Leboyer M, Fond G. Mood disorders are associated with a more severe hypovitaminosis D than schizophrenia. Psychiatry Res. 2015;229:613-6. doi: 10.1016/j.psychres.2015.04.039. PubMed PMID: 26027439.
  7. Fond G, Faugere M, Faget-Agius C, Cermolacce M, Richieri R, Boyer L, et al. Hypovitaminosis D is associated with negative symptoms, suicide risk, agoraphobia, impaired functional remission, and antidepressant consumption in schizophrenia. Eur Arch Psychiatry Clin Neurosci. 2019;269:879-86. doi: 10.1007/s00406-018-0932-0. PubMed PMID: 30078128.
  8. Umhau JC, George DT, Heaney RP, Lewis MD, Ursano RJ, Heilig M, et al. Low vitamin D status and suicide: a case-control study of active duty military service members. PLoS One. 2013;8:e51543. doi: 10.1371/journal.pone.0051543. PubMed PMID: 23308099; PubMed Central PMCID: PMCPMC3537724.
  9. Calderon Espinoza I, Chavarria-Avila E, Pizano-Martinez O, Martinez-Garcia EA, Armendariz-Borunda J, Marquez-Aguirre AL, et al. Suicide Risk in Rheumatoid Arthritis Patients is Associated With Suboptimal Vitamin D Levels. J Clin Rheumatol. 2022;28:137-42. doi: 10.1097/RHU.0000000000001823. PubMed PMID: 35293886; PubMed Central PMCID: PMCPMC8946603.
  10. Park JI, Yang JC, Won Park T, Chung SK. Is serum 25-hydroxyvitamin D associated with depressive symptoms and suicidal ideation in Korean adults? Int J Psychiatry Med. 2016;51:31-46. doi: 10.1177/0091217415621042. PubMed PMID: 26681234.
  11. Kiadaliri AA, Saadat S, Shahnavazi H, Haghparast-Bidgoli H. Overall, gender and social inequalities in suicide mortality in Iran, 2006-2010: a time trend province-level study. BMJ Open. 2014;4:e005227. doi: 10.1136/bmjopen-2014-005227. PubMed PMID: 25138804; PubMed Central PMCID: PMCPMC4139655.
  12. Shohani M, Mansouri A, Azami M, Soleymani A, Badfar G. The study of vitamin D Status in population referred to clinical laboratories in ilam, west of Iran. Crescent J Med Biol Sci. 2018;5:115-8. 
  13. Bucova M, Durmanova V, Cudrakova D, Blazickova S, Gmitterova K, Klimova E, et al. Decreased plasma levels of 25(OH)D in multiple sclerosis patients. Correlation with disease severity expressed by EDSS, MSSS, progression index and Herbert s scale severity grade. Bratisl Lek Listy. 2019;120:723-9. doi: 10.4149/BLL_2019_120. PubMed PMID: 31663345.
  14. Gokalp G. The association between low vitamin D levels and suicide attempts in adolescents. Ann Clin Psychiatry. 2020;32:106-13. PubMed PMID: 32384132.
  15. Kim SY, Jeon SW, Lim WJ, Oh KS, Shin DW, Cho SJ, et al. Vitamin D deficiency and suicidal ideation: A cross-sectional study of 157,211 healthy adults. J Psychosom Res. 2020;134:110125. doi: 10.1016/j.jpsychores.2020.110125. PubMed PMID: 32388454.
آمار
تعداد مشاهده مقاله: 24
تعداد دریافت فایل اصل مقاله: 23


سامانه مدیریت نشریات علمی. قدرت گرفته از سیناوب