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Sadeghi, Abolfazl, Bayazidi, Yahya, Davari, Majid, Kebriaeezadeh, Abbas, Assarian, Amin, Esteghamati, Alireza, Yousefi, Sepideh. (1401). Individualized Glycemic Control in Type 2 Diabetic Patients in Iran: A Multi-Center Data Analysis. سامانه مدیریت نشریات علمی, (), -. doi: 10.30476/ijms.2022.92805.2409
Abolfazl Sadeghi; Yahya Bayazidi; Majid Davari; Abbas Kebriaeezadeh; Amin Assarian; Alireza Esteghamati; Sepideh Yousefi. "Individualized Glycemic Control in Type 2 Diabetic Patients in Iran: A Multi-Center Data Analysis". سامانه مدیریت نشریات علمی, , , 1401, -. doi: 10.30476/ijms.2022.92805.2409
Sadeghi, Abolfazl, Bayazidi, Yahya, Davari, Majid, Kebriaeezadeh, Abbas, Assarian, Amin, Esteghamati, Alireza, Yousefi, Sepideh. (1401). 'Individualized Glycemic Control in Type 2 Diabetic Patients in Iran: A Multi-Center Data Analysis', سامانه مدیریت نشریات علمی, (), pp. -. doi: 10.30476/ijms.2022.92805.2409
Sadeghi, Abolfazl, Bayazidi, Yahya, Davari, Majid, Kebriaeezadeh, Abbas, Assarian, Amin, Esteghamati, Alireza, Yousefi, Sepideh. Individualized Glycemic Control in Type 2 Diabetic Patients in Iran: A Multi-Center Data Analysis. سامانه مدیریت نشریات علمی, 1401; (): -. doi: 10.30476/ijms.2022.92805.2409

Individualized Glycemic Control in Type 2 Diabetic Patients in Iran: A Multi-Center Data Analysis

Iranian Journal of Medical Sciences
مقالات آماده انتشار، اصلاح شده برای چاپ، انتشار آنلاین از تاریخ 28 دی 1401  XML اصل مقاله (270.77 K)
نوع مقاله: Original Article(s)
شناسه دیجیتال (DOI): 10.30476/ijms.2022.92805.2409
نویسندگان
Abolfazl Sadeghiorcid 1؛ Yahya Bayazidi email orcid 1؛ Majid Davari1؛ Abbas Kebriaeezadeh1؛ Amin Assarian1؛ Alireza Esteghamati2؛ Sepideh Yousefi3
1Department of Pharmacoeconomics and Pharmaceutical Administration, School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
2Endocrinology and Metabolism Research Center, Vali-Asr Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
3School of Pharmacy and Pharmaceutical Science, Islamic Azad University, Tehran, Iran
چکیده
Background: Clinical guidelines and expert committees have recently suggested that the hemoglobin A1C (HbA1c) should be individualized based on various criteria. Data regarding the achievement of individualized glycemic targets in type 2 diabetes (T2DM) patients is scant in Iran. We intended to provide information found on real-world outcomes from the perspective of an individualized recommendation.
Methods: A cross-sectional analysis was conducted in 15 diabetes centers in Iran between 2013-2017. Two steps cluster sampling selection was used to recruit 1591 patients with type 2 diabetes mellitus. Considering Ismail-Beigi’s individualized strategy, the study population was categorized into five treatment intensities of HbA1c: most intensive (≤6.5%), intensive (6.5–7.0%), less intensive (~7.0%), not intensive (7.0–8.0%), and moderated (~8.0%). The percentage of patients who met their group individualized glycemic targets was estimated as the degree of achievement of each treatment intensity.
Results: The cumulative incidence rate of early microvascular, advanced microvascular, and macrovascular complications was 53%, 25%, and 34%, respectively. Besides, 78% [77.6-79%] of patients did not achieve individualized glycemic targets. 
Conclusion: The outcome showed poor individualized glycemic control and a high incidence of diabetes complications. Considering individualized HbA1c targets for Iranian patients with T2DM is an urgent need.  
کلیدواژه‌ها
Diabetes mellitus؛ Individualized glycemic control؛ Precision medicine؛ Diabetes complications
مراجع
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