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Heshmat, Haleh, Kazemi Yazdi, Haleh, Hoorizad Ganjkar, Maryam, Chaboki, Farhad, Shokri, Mahoor, Kharazifard, Mohamad Javad. (1401). Effect of Two Remineralizing Agents on Dentin Microhardness of Non-Caries Lesions. سامانه مدیریت نشریات علمی, (), -. doi: 10.30476/dentjods.2023.95663.1883
Haleh Heshmat; Haleh Kazemi Yazdi; Maryam Hoorizad Ganjkar; Farhad Chaboki; Mahoor Shokri; Mohamad Javad Kharazifard. "Effect of Two Remineralizing Agents on Dentin Microhardness of Non-Caries Lesions". سامانه مدیریت نشریات علمی, , , 1401, -. doi: 10.30476/dentjods.2023.95663.1883
Heshmat, Haleh, Kazemi Yazdi, Haleh, Hoorizad Ganjkar, Maryam, Chaboki, Farhad, Shokri, Mahoor, Kharazifard, Mohamad Javad. (1401). 'Effect of Two Remineralizing Agents on Dentin Microhardness of Non-Caries Lesions', سامانه مدیریت نشریات علمی, (), pp. -. doi: 10.30476/dentjods.2023.95663.1883
Heshmat, Haleh, Kazemi Yazdi, Haleh, Hoorizad Ganjkar, Maryam, Chaboki, Farhad, Shokri, Mahoor, Kharazifard, Mohamad Javad. Effect of Two Remineralizing Agents on Dentin Microhardness of Non-Caries Lesions. سامانه مدیریت نشریات علمی, 1401; (): -. doi: 10.30476/dentjods.2023.95663.1883

Effect of Two Remineralizing Agents on Dentin Microhardness of Non-Caries Lesions

Journal of Dentistry
مقالات آماده انتشار، پذیرفته شده، انتشار آنلاین از تاریخ 27 دی 1401  XML اصل مقاله (262.14 K)
نوع مقاله: Original Article
شناسه دیجیتال (DOI): 10.30476/dentjods.2023.95663.1883
نویسندگان
Haleh Heshmatorcid 1؛ Haleh Kazemi Yazdiorcid 2؛ Maryam Hoorizad Ganjkarorcid 2؛ Farhad Chaboki email orcid 3؛ Mahoor Shokriorcid 4؛ Mohamad Javad Kharazifardorcid 5
1Dept. of Restorative Dentistry, Member of Dental Material Research Center, Islamic Azad University of Medical Sciences, Tehran, Iran.
2Dept. of Restorative Dentistry, School of Dentistry, Islamic Azad University of Medical Sciences, Tehran, Iran.
3Postgraduate Student, School of Dentistry, Islamic Azad University of Medical Sciences, Tehran, Iran.
4School of Dentistry, Islamic Azad University of Medical Sciences, Tehran, Iran.
5Dental Research Center, Tehran University of Medical Sciences, Tehran, Iran.
چکیده
Statement of the Problem: The prevalence of non-carious dentin lesions is on the rise mainly due to improved life expectancy. Successful management of these lesions is often challenging, and given that dentin can be remineralized, adverse consequences due to progression of these lesions can be prevented or minimized as such.
Purpose: This study aimed to assess the effect of casein phosphopeptide amorphous calcium phosphate (CPP-ACP) and Remin-Pro remineralizing agents on dentin microhardness of non-carious dentin lesions.
Materials and Method: This in vitro, experimental study evaluated 36 extracted sound human premolars. The teeth were decoronated at the cementoenamel junction. Enamel was removed, and dentin was exposed at the cervical third of the buccal surface. The primary microhardness of dentin was then measured. The teeth, standardized in terms of dentin microhardness, then underwent demineralization by acid etching and were subjected to microhardness test again. They were then randomized into three groups for treatment with CPP-ACP, Remin-Pro, and artificial saliva (control), and dentin microhardness was measured for the third time after treatment. Data were analyzed using ANOVA.
Results: Within group comparisons showed a significant difference in microhardness at the three time points in all three groups (p< 0.005). Between-group comparisons revealed that the microhardness of the three groups was not significantly different at baseline or after demineralization. However, the microhardness of the three groups was significantly different after the intervention (p= 0.000). Pairwise comparisons revealed significantly higher microhardness in the CPP-ACP group than the other two groups (p= 0.003). Remin-Pro and the control groups were not significantly different in this respect (p= 0.340).
Conclusion: CPP-ACP can be used for remineralization of non-caries dentin lesions; however, Remin-Pro does not appear to be effective for this purpose. 
کلیدواژه‌ها
CPP-ACP؛ Dentin؛ Hardness؛ Hydroxyapatites؛ Tooth Remineralization
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