Right Ventricular Function Indices at Rest and During Exercise in Hyperthyroid Patients: A Cross-sectional Study | ||
| Iranian Journal of Medical Sciences | ||
| مقاله 9، دوره 48، شماره 3، مرداد 2023، صفحه 313-320 اصل مقاله (548.88 K) | ||
| نوع مقاله: Original Article(s) | ||
| شناسه دیجیتال (DOI): 10.30476/ijms.2022.92556.2389 | ||
| نویسندگان | ||
| Khadije Mohammadi* 1؛ Maryam Shojaeifard2؛ Marzieh Mirtajaddini3؛ Hamidreza Hekmat4؛ Zahra Davoudi5؛ Azam Erfanifar5 | ||
| 1Cardiovascular Research Center, Kerman University of Medical Sciences, Kerman, Iran | ||
| 2Echocardiography Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran | ||
| 3Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran | ||
| 4School of Medicine, Ziaeian Hospital, International Campus, Tehran University of Medical Sciences, Tehran, Iran | ||
| 5Department of Endocrinology, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran | ||
| چکیده | ||
| Background: Since hyperthyroidism could be associated with right ventricular dysfunction, this study intended to investigate right ventricular (RV) function using strain echocardiography in hyperthyroid patients both at rest and in maximum-stress conditions. Methods: This cross-sectional study was conducted at Rajaie Cardiovascular Medical and Research Center, Tehran, Iran, from January 2019 to January 2020. All study participants completed a maximum treadmill exercise test, as well as a complete two-dimensional echocardiogram at rest and the peak of stress test. The data were analyzed using SPSS statistical software. The independent samples t test and Mann–Whitney U test were used for numerical, and the Chi square test was used for nominal variables. P<0.05 was considered statistically significant. Results: The final analysis included 52 participants (26 subjects in each group). In a maximal stress situation, we found that among the RV function indices, RV global longitudinal strain (P=0.0001), systolic strain rate (P=0.0001), diastolic strain rate (P=0.0002), and tricuspid annular plane systolic excursion (P=0.019) were reduced significantly in the hyperthyroid patients compared to the control group. There was also a linear correlation between RV size and thyroid stimulating hormone (TSH) level (P=0.009, r=0.36). Moreover, we found a negative linear correlation between TSH level with maximum stress RV strain and diastolic strain rate (P<0.001). Conclusion: The findings of the present study revealed a significant change in RV function indices among hyperthyroid patients. Therefore, it highlights the necessity of early diagnosis and treatment of hyperthyroidism, as well as RV function evaluation in these patients. | ||
| کلیدواژهها | ||
| Ventricular function, right؛ Hyperthyroidism؛ Exercise test؛ Echocardiography | ||
| مراجع | ||
|
| ||
|
آمار تعداد مشاهده مقاله: 2,944 تعداد دریافت فایل اصل مقاله: 1,066 |
||