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Mohammadi, Khadije, Shojaeifard, Maryam, Mirtajaddini, Marzieh, Hekmat, Hamidreza, Davoudi, Zahra, Erfanifar, Azam. (1402). Right Ventricular Function Indices at Rest and During Exercise in Hyperthyroid Patients: A Cross-sectional Study. سامانه مدیریت نشریات علمی, 48(3), 313-320. doi: 10.30476/ijms.2022.92556.2389
Khadije Mohammadi; Maryam Shojaeifard; Marzieh Mirtajaddini; Hamidreza Hekmat; Zahra Davoudi; Azam Erfanifar. "Right Ventricular Function Indices at Rest and During Exercise in Hyperthyroid Patients: A Cross-sectional Study". سامانه مدیریت نشریات علمی, 48, 3, 1402, 313-320. doi: 10.30476/ijms.2022.92556.2389
Mohammadi, Khadije, Shojaeifard, Maryam, Mirtajaddini, Marzieh, Hekmat, Hamidreza, Davoudi, Zahra, Erfanifar, Azam. (1402). 'Right Ventricular Function Indices at Rest and During Exercise in Hyperthyroid Patients: A Cross-sectional Study', سامانه مدیریت نشریات علمی, 48(3), pp. 313-320. doi: 10.30476/ijms.2022.92556.2389
Mohammadi, Khadije, Shojaeifard, Maryam, Mirtajaddini, Marzieh, Hekmat, Hamidreza, Davoudi, Zahra, Erfanifar, Azam. Right Ventricular Function Indices at Rest and During Exercise in Hyperthyroid Patients: A Cross-sectional Study. سامانه مدیریت نشریات علمی, 1402; 48(3): 313-320. doi: 10.30476/ijms.2022.92556.2389

Right Ventricular Function Indices at Rest and During Exercise in Hyperthyroid Patients: A Cross-sectional Study

Iranian Journal of Medical Sciences
مقاله 9، دوره 48، شماره 3، مرداد 2023، صفحه 313-320    اصل مقاله (548.88 K)
نوع مقاله: Original Article(s)
شناسه دیجیتال (DOI): 10.30476/ijms.2022.92556.2389
نویسندگان
Khadije Mohammadi* 1؛ Maryam Shojaeifard2؛ Marzieh Mirtajaddini3؛ Hamidreza Hekmat4؛ Zahra Davoudi5؛ Azam Erfanifar5
1Cardiovascular Research Center, Kerman University of Medical Sciences, Kerman, Iran
2Echocardiography Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran
3Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran
4School of Medicine, Ziaeian Hospital, International Campus, Tehran University of Medical Sciences, Tehran, Iran
5Department of Endocrinology, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran
چکیده
Background: Since hyperthyroidism could be associated with right ventricular dysfunction, this study intended to investigate right ventricular (RV) function using strain echocardiography in hyperthyroid patients both at rest and in maximum-stress conditions. 
Methods: This cross-sectional study was conducted at Rajaie Cardiovascular Medical and Research Center, Tehran, Iran, from January 2019 to January 2020. All study participants completed a maximum treadmill exercise test, as well as a complete two-dimensional echocardiogram at rest and the peak of stress test. The data were analyzed using SPSS statistical software. The independent samples t test and Mann–Whitney U test were used for numerical, and the Chi square test was used for nominal variables. P<0.05 was considered statistically significant. 
Results: The final analysis included 52 participants (26 subjects in each group). In a maximal stress situation, we found that among the RV function indices, RV global longitudinal strain (P=0.0001), systolic strain rate (P=0.0001), diastolic strain rate (P=0.0002), and tricuspid annular plane systolic excursion (P=0.019) were reduced significantly in the hyperthyroid patients compared to the control group. There was also a linear correlation between RV size and thyroid stimulating hormone (TSH) level (P=0.009, r=0.36). Moreover, we found a negative linear correlation between TSH level with maximum stress RV strain and diastolic strain rate (P<0.001).
Conclusion: The findings of the present study revealed a significant change in RV function indices among hyperthyroid patients. Therefore, it highlights the necessity of early diagnosis and treatment of hyperthyroidism, as well as RV function evaluation in these patients.
کلیدواژه‌ها
Ventricular function, right؛ Hyperthyroidism؛ Exercise test؛ Echocardiography
سایر فایل های مرتبط با مقاله
مراجع
  1. Ahmed R. Hyperthyroidism and developmental dysfunction. Archives of Medicine. 2017;9:6.
  2. Jabbar A, Ingoe L, Junejo S, Carey P, Addison C, Thomas H, et al. Effect of Levothyroxine on Left Ventricular Ejection Fraction in Patients With Subclinical Hypothyroidism and Acute Myocardial Infarction: A Randomized Clinical Trial. JAMA. 2020;324:249-58. doi: 10.1001/jama.2020.9389. PubMed PMID: 32692386.
  3. Shojaeifard M, Davoudi Z, Erfanifar A, Fattahi Neisiani H, Erami S, Bakhshandeh H, et al. Evaluation of diastolic function in newly diagnosed hyperthyroid patients with preserved left ventricular systolic function. Cardiovasc Endocrinol Metab. 2021;10:186-90. doi: 10.1097/XCE.0000000000000238. PubMed PMID: 34386721; PubMed Central PMCID: PMCPMC8352617.
  4. Shojaeifard M, Davoudi Z, Erfanifar A, Karamali F, Fattahi Neisiani H, Habibi Khorasani S, et al. Comparison of myocardial deformation indices during rest and after activity in untreated hyperthyroid patients with normal population. Am J Cardiovasc Dis. 2020;10:230-40. PubMed PMID: 32923105; PubMed Central PMCID: PMCPMC7486525.
  5. Klein I, Danzi S. Thyroid Disease and the Heart. Curr Probl Cardiol. 2016;41:65-92. doi: 10.1016/j.cpcardiol.2015.04.002. PubMed PMID: 26792255.
  6. Collet TH, Gussekloo J, Bauer DC, den Elzen WP, Cappola AR, Balmer P, et al. Subclinical hyperthyroidism and the risk of coronary heart disease and mortality. Arch Intern Med. 2012;172:799-809. doi: 10.1001/archinternmed.2012.402. PubMed PMID: 22529182; PubMed Central PMCID: PMCPMC3872478.
  7. Moon S, Kong SH, Choi HS, Hwangbo Y, Lee MK, Moon JH, et al. Relation of Subclinical Hypothyroidism is Associated With Cardiovascular Events and All-Cause Mortality in Adults With High Cardiovascular Risk. Am J Cardiol. 2018;122:571-7. doi: 10.1016/j.amjcard.2018.03.371. PubMed PMID: 29980273.
  8. Selmer C, Olesen JB, Hansen ML, von Kappelgaard LM, Madsen JC, Hansen PR, et al. Subclinical and overt thyroid dysfunction and risk of all-cause mortality and cardiovascular events: a large population study. J Clin Endocrinol Metab. 2014;99:2372-82. doi: 10.1210/jc.2013-4184. PubMed PMID: 24654753.
  9. Khairat I, Khalfallah M, Shaban A, Farag IA, Elkady A. Right ventricular 2D speckle-tracking echocardiography in children with osteosarcoma under chemotherapy. Egypt Heart J. 2019;71:23. doi: 10.1186/s43044-019-0028-9. PubMed PMID: 31748972; PubMed Central PMCID: PMCPMC6868075.
  10. Allison JD, Zehner C, Jia X, Hamzeh IR, Alam M, Nair A, et al. Assessing the Validity of Echocardiographic Criteria for Left Ventricular Diastolic Dysfunction in Patients with Pulmonary Hypertension. Cardiology. 2020;145:703-9. doi: 10.1159/000510348. PubMed PMID: 33032287.
  11. Yang G, Wang Y, Ma A, Wang T. Subclinical thyroid dysfunction is associated with adverse prognosis in heart failure patients with reduced ejection fraction. BMC Cardiovasc Disord. 2019;19:83. doi: 10.1186/s12872-019-1055-x. PubMed PMID: 30947691; PubMed Central PMCID: PMCPMC6450005.
  12. Suk JH, Cho KI, Lee SH, Lee HG, Kim SM, Kim TI, et al. Prevalence of echocardiographic criteria for the diagnosis of pulmonary hypertension in patients with Graves’ disease: before and after antithyroid treatment. J Endocrinol Invest. 2011;34:e229-34. doi: 10.3275/7573. PubMed PMID: 21399392.
  13. Gerges M, Gerges C, Pistritto AM, Lang MB, Trip P, Jakowitsch J, et al. Pulmonary Hypertension in Heart Failure. Epidemiology, Right Ventricular Function, and Survival. Am J Respir Crit Care Med. 2015;192:1234-46. doi: 10.1164/rccm.201503-0529OC. PubMed PMID: 26181215.
  14. Kendsersky P, Ward C. Right Ventricular Failure and Congenital Heart Disease. Cardiol Clin. 2020;38:239-42. doi: 10.1016/j.ccl.2020.02.002. PubMed PMID: 32284100.
  15. Bootsma IT, de Lange F, Koopmans M, Haenen J, Boonstra PW, Symersky T, et al. Right Ventricular Function After Cardiac Surgery Is a Strong Independent Predictor for Long-Term Mortality. J Cardiothorac Vasc Anesth. 2017;31:1656-62. doi: 10.1053/j.jvca.2017.02.008. PubMed PMID: 28416392.
  16. Jabbar A, Pingitore A, Pearce SH, Zaman A, Iervasi G, Razvi S. Thyroid hormones and cardiovascular disease. Nat Rev Cardiol. 2017;14:39-55. doi: 10.1038/nrcardio.2016.174. PubMed PMID: 27811932.
  17. Kachenoura N, Bollache E, Soulat G, Clement-Guinaudeau S, Ashrafpoor G, Perdrix L, et al. Right ventricular diastolic function in aging: a head-to-head comparison between phase-contrast MRI and Doppler echocardiography. Int J Cardiovasc Imaging. 2021;37:663-74. doi: 10.1007/s10554-020-02040-y. PubMed PMID: 32980983.
  18. Wright L, Dwyer N, Power J, Kritharides L, Celermajer D, Marwick TH. Right Ventricular Systolic Function Responses to Acute and Chronic Pulmonary Hypertension: Assessment with Myocardial Deformation. J Am Soc Echocardiogr. 2016;29:259-66. doi: 10.1016/j.echo.2015.11.010. PubMed PMID: 26944627.
  19. Malagoli A, Fanti D, Albini A, Rossi A, Ribichini FL, Benfari G. Echocardiographic Strain Imaging in Coronary Artery Disease: The Added Value of a Quantitative Approach. Cardiol Clin. 2020;38:517-26. doi: 10.1016/j.ccl.2020.06.005. PubMed PMID: 33036714.
  20. Grabka M, Wita K, Tabor Z, Paraniak-Gieszczyk B, Chmurawa J, Elzbieciak M, et al. Prediction of infarct size by speckle tracking echocardiography in patients with anterior myocardial infarction. Coron Artery Dis. 2013;24:127-34. doi: 10.1097/MCA.0b013e32835b6798. PubMed PMID: 23324905.
  21. Robert Wood [Internet]. Bruce Protocol Treadmill Stress Test. c2008. [Cited 1 August 2022]. Avilable from: https://www.topendsports.com/testing/tests/bruce.htm
  22. Pellikka PA, Arruda-Olson A, Chaudhry FA, Chen MH, Marshall JE, Porter TR, et al. Guidelines for Performance, Interpretation, and Application of Stress Echocardiography in Ischemic Heart Disease: From the American Society of Echocardiography. J Am Soc Echocardiogr. 2020;33:1-41. doi: 10.1016/j.echo.2019.07.001. PubMed PMID: 31740370.
  23. Singarayar CS, Siew Hui F, Cheong N, Swee En G. Right ventricular dysfunction and pulmonary hypertension: a neglected presentation of thyrotoxicosis. Endocrinol Diabetes Metab Case Rep. 2018;2018. doi: 10.1530/EDM-18-0012. PubMed PMID: 29785271; PubMed Central PMCID: PMCPMC5955009.
  24. Kubra K, Sindhuri PK, Vaidyanathan R, Adarsh S, Shridhara T. Undiagnosed Thyrotoxicosis Masquerading as Heart Failure. RGUHS Journal of Allied Health Sciences. 2021;1.
  25. Tadic M, Celic V, Cuspidi C, Ilic S, Zivanovic V, Marjanovic T. How Does Subclinical Hyperthyroidism Affect Right Heart Function and Mechanics? J Ultrasound Med. 2016;35:287-95. doi: 10.7863/ultra.15.03054. PubMed PMID: 26715657.
  26. Gazzana ML, Souza JJ, Okoshi MP, Okoshi K. Prospective Echocardiographic Evaluation of the Right Ventricle and Pulmonary Arterial Pressure in Hyperthyroid Patients. Heart Lung Circ. 2019;28:1190-6. doi: 10.1016/j.hlc.2018.06.1055. PubMed PMID: 30262155.
  27. Arinc H, Gunduz H, Tamer A, Seyfeli E, Kanat M, Ozhan H, et al. Evaluation of right ventricular function in patients with thyroid dysfunction. Cardiology. 2006;105:89-94. doi: 10.1159/000089855. PubMed PMID: 16319454.
  28. Nacar AB, Acar G, Yorgun H, Akcay A, Ozkaya M, Canpolat U, et al. The effect of antithyroid treatment on atrial conduction times in patients with subclinical hyperthyroidism. Echocardiography. 2012;29:950-5. doi: 10.1111/j.1540-8175.2012.01718.x. PubMed PMID: 22640277.
  29. Faccia M, Porfidia A, Montalto M. Acute Right Ventricular Heart Failure: An Uncommon Case of Thyrotoxicosis. Am J Med Sci. 2018;356:309-12. doi: 10.1016/j.amjms.2018.03.017. PubMed PMID: 30139580.
  30. Khan R, Sikanderkhel S, Gui J, Adeniyi AR, O’Dell K, Erickson M, et al. Thyroid and Cardiovascular Disease: A Focused Review on the Impact of Hyperthyroidism in Heart Failure. Cardiol Res. 2020;11:68-75. doi: 10.14740/cr1034. PubMed PMID: 32256913; PubMed Central PMCID: PMCPMC7092768.
  31. Razvi S, Jabbar A, Pingitore A, Danzi S, Biondi B, Klein I, et al. Thyroid Hormones and Cardiovascular Function and Diseases. J Am Coll Cardiol. 2018;71:1781-96. doi: 10.1016/j.jacc.2018.02.045. PubMed PMID: 29673469.
  32. Teasdale SL, Inder WJ, Stowasser M, Stanton T. Hyperdynamic Right Heart Function in Graves’ Hyperthyroidism Measured by Echocardiography Normalises on Restoration of Euthyroidism. Heart Lung Circ. 2017;26:580-5. doi: 10.1016/j.hlc.2016.10.007. PubMed PMID: 28025026.
  33. Polito MV, Stoebe S, Galasso G, De Rosa R, Citro R, Piscione F, et al. Analysis of Regional Right Ventricular Function by Tissue Doppler Imaging in Patients with Aortic Stenosis. J Cardiovasc Echogr. 2019;29:111-8. doi: 10.4103/jcecho.jcecho_27_19. PubMed PMID: 31728301; PubMed Central PMCID: PMCPMC6829760.
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