|تعداد مشاهده مقاله||10,696,904|
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Behavior and Prognosis of Ovarian Cancer with Rare Metastatic Sites
|Middle East Journal of Cancer|
|مقالات آماده انتشار، پذیرفته شده، انتشار آنلاین از تاریخ 29 آذر 1401 اصل مقاله (336.67 K)|
|نوع مقاله: Original Article|
|شناسه دیجیتال (DOI): 10.30476/mejc.2022.94344.1721|
|Mohammad Zuhdy 1؛ Reham Alghandour 2؛ Omar Hamdy 1؛ Islam Metwally H. Metwally 2|
|1Surgical Oncology Unit, Oncology Centre Mansoura University (OCMU), Mansoura, Egypt|
|2Medical Oncology Unit, Oncology Centre Mansoura University (OCMU), Mansoura, Egypt|
|Background: Ovarian cancer is the most prevalent gynecologic malignancy in Egypt. Although metastasis from ovarian cancer is common, there are still sites with rarely reported deposits as non-regional nodes, bone, and brain.|
Method: We retrospectively recruited a group of patients over a 7-year period from the data system of a cancer center. All the recruited patients suffered from a rare distant metastasis from ovarian cancer. We used statistical software (SPSS) for the analysis of the study results. Continuous variables were presented as mean and standard deviation if normally distributed, or median and range when non-normally distributed. Independent samples t-test was utilized to compare parametric data whereas non-parametric data were compared through the use of the Mann-Whitney U test. Categorical data were compared with Pearson's Chi-square test or Fischer-Exact test when appropriate. A P-value ˂ 0.05 was considered to be statistically significant.
Results: Nearly half of the patients already had metastasis at the time of the initial presentation while the rest developed it during the disease course. Debulking was feasible in nearly half of the patients with long overall and progression-free survival. Tumors with non-regional nodal metastases seemed to have excellent survival.
Conclusion: We could recommend offering these patients optimal debulking and considering those with a non-regional nodal spread as having a curable disease.
|Ovarian neoplasms؛ Cytoreduction surgical procedure؛ Rare diseases؛ Lymphatic metastases|
This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination, and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi:10.30476/mejc.2022.94344.1721
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