LinkedIn

 آمار

تعداد نشریات20
تعداد شماره‌ها1,149
تعداد مقالات10,518
تعداد مشاهده مقاله45,415,529
تعداد دریافت فایل اصل مقاله11,291,333
Nazari, Farzaneh, Parsaiyan, Zahra, Rezaei, Leyla, Mohammadpour, Mahshid, Mirzaei, Kamran. (1401). Comparison of Serum Hormone Levels in Pilonidal Sinus Disease Patients by Gender. سامانه مدیریت نشریات علمی, 10(3), 87-91. doi: 10.30476/acrr.2022.96599.1152
Farzaneh Nazari; Zahra Parsaiyan; Leyla Rezaei; Mahshid Mohammadpour; Kamran Mirzaei. "Comparison of Serum Hormone Levels in Pilonidal Sinus Disease Patients by Gender". سامانه مدیریت نشریات علمی, 10, 3, 1401, 87-91. doi: 10.30476/acrr.2022.96599.1152
Nazari, Farzaneh, Parsaiyan, Zahra, Rezaei, Leyla, Mohammadpour, Mahshid, Mirzaei, Kamran. (1401). 'Comparison of Serum Hormone Levels in Pilonidal Sinus Disease Patients by Gender', سامانه مدیریت نشریات علمی, 10(3), pp. 87-91. doi: 10.30476/acrr.2022.96599.1152
Nazari, Farzaneh, Parsaiyan, Zahra, Rezaei, Leyla, Mohammadpour, Mahshid, Mirzaei, Kamran. Comparison of Serum Hormone Levels in Pilonidal Sinus Disease Patients by Gender. سامانه مدیریت نشریات علمی, 1401; 10(3): 87-91. doi: 10.30476/acrr.2022.96599.1152

Comparison of Serum Hormone Levels in Pilonidal Sinus Disease Patients by Gender

Iranian Journal of Colorectal Research
مقاله 2، دوره 10، شماره 3، آذر 2022، صفحه 87-91    اصل مقاله (465.17 K)
نوع مقاله: Research/Original Article
شناسه دیجیتال (DOI): 10.30476/acrr.2022.96599.1152
نویسندگان
Farzaneh Nazari1؛ Zahra Parsaiyan* 2؛ Leyla Rezaei3؛ Mahshid Mohammadpour4؛ Kamran Mirzaei5
1Department of Obstetrics and Gynecology, perinatology unit. Boushehr university of medical sciences, Boushehr, Iran
2Department of Obstetrics and Gynecology. Deylam baqiyatallah hospital, Boushehr, Iran
3Department of general surgery, Boushehr university of medical sciences, Boushehr, Iran
4Department of Obstetrics and Gynecology, Boushehr university of medical sciences, Boushehr, Iran
5Community Medicine department, Boushehr University of Medical Sciences, Boushehr, Iran
چکیده
Background: Pilonidal sinus disease (PSD) describes an inflammation of the subcutaneous fatty tissue causing a pilonidal sinus which can lead to pus collection and tenderness. The study objective was to investigate the relationship between serum hormones, PSD and associated factors in patients referring to Khalij Fars hospital in Bushehr city, Iran in 2017.
Methods: A cross-sectional study consisted of 50 patients with pilonidal sinus disease who underwent surgery in Khalij Fars hospital in Bushehr city, Iran between February and May 2017 was conducted. The patients with SPD who consented to participate in the study were enrolled in the research and subjected to review their physical signs and medical history. Hormone levels (including the serum levels of luteinizing hormone (LH), follicle-stimulating hormone (FSH), total testosterone, dehydroepiandrosterone (DHEA), and prolactin) were measured.
Results: The level of sex hormones in female patients was significantly higher in comparison with males except for testosterone (3.9±1.73 in male; 0.35±0.17 in females). The frequency of patients with normal serum levels of LH, testosterone, and prolactin was higher in females than those in the male group, whereas the rate of those with normal levels of FSH, DHEAS, and Prolactin in male patient group was higher, compared with the female group (P<0.05).
Conclusion: As there are a few studies conducted on hormonal status of patients with pilonidal sinus by genders, we conducted the current study, to compare serum levels between male and female patients. Raised serum prolactin, LH, and testosterone levels in women might be contributed to increasing androgen levels and causing excessive hair growth/ hirsutism.
کلیدواژه‌ها
Pilonidal sinus disease؛ pilonidal sinus؛ gender؛ age؛ sex hormones؛ BMI
مراجع
  1.  Doll, D. et al. Strength of occipital hair as an explanation for pilonidal sinus disease caused by intruding hair. DCR 60, 979–986.
  2. Altintoprak F, Gundogdu K, Ergonenc T, Dikicier E, Cakmak G, Celebi F. Retrospective review of pilonidal sinus patients with early discharge after Limberg flap procedure. Int Surg 2014;99:28–34.
  3. Page, B. H. The entry of hair into a pilonidal sinus. Br. J. Surg 1969; 56, 32.
  4. Chintapalta S, Safarani N, Kumar S, Haboubi N. Sacrococcygeal pilonidal sinus: historical review, pathological insight and surgical options. Tech Coloproctol 2003; 7: 3– 8.
  5. Nasr A, Sigmund HE. A pediatric surgeon’s 35-year experience with pilonidal disease in a Canadian children’s hospital. Can J Surg 2011; 54:39–42.
  6. Özkan Z, Aksoy N, Emir S., Kanat B. H., Gönen A. N., Yazar F. M., et al. Investigation of the relationship between serum hormones and pilonidal sinus disease: a cross-sectional study Colorectal Disease 2014; 16(4): 311-314.
  7. Jones DJ. ABC of colorectal diseases. Pilonidal sinus.                      BMJ 1992; 305: 410– 2.
  8. Mortimer PS, Dawber RPR, Gales MA, Moore RA. Mediation of hidradenitis suppurativa androgens. Br Med J (Clin Res Ed) 1986; 292: 245– 8.
  9. Rosenfield RL. Clinical practice. Hirsutism.                                          N Engl J Med 2005; 353: 2578– 88.
  10. Seppala M, Hirnoven E. Raised serum prolactin levels with hirsutism and amenorrhoea. Br Med J 1975; 4: 144– 5.
  11. National Health System. What is the body mass index (BMI)? available at https://www.nhs.uk/common-healthquestions/lifestyle/what-is-the-bodymass-index-bmi/, accessed in August 16, 2022.
  12. Test ID: TTFB-testosterone, total, bioavailable, and free, serum. (n.d.). mayomedicallaboratories. com/test-catalog /Clinical+and+Interpretive/83686.
  13. University of Rochester Medical Center, Health Encyclopedia. Luteinizing Hormone (Blood), available at https://www.urmc. rochester.edu/encyclopedia/content. aspx?ContentTypeID=167&Content ID=luteinizing_hormone_blood.
  14. Lobo RA. Infertility: etiology, diagnostic evaluation, management, prognosis. In: Lobo RA, Gershenson DM, Lentz GM, Valea FA, eds. Comprehensive Gynecology. 7th ed. Philadelphia, PA: Elsevier; 2017: chap 42.
  15. Maleki A, Rashidi N, Aghaei Meybodi H, Montazeri M, Montazeri M, Falsafi F, et al. Metabolic syndrome and inflammatory biomarkers in adults: A population-based survey in western region of Iran. Int Cardiovasc Res J. 2014;8:156–60.
  16. Kaymakcioglu N, Yagci G., Simsek A., Unlu A., Tekin O.F., Cetiner S., et al. Treatment of pilonidal sinus by phenol application and factors affecting the recurrence, Tech. Coloproctol. 9 (1) (2005) 21–24.
  17.  Arda I.S., Güney L.H., Sevmiş Ş,  Hiçsönmez A. High body mass index as a possible risk factor for pilonidal sinus disease in adolescents, World J. Surg. 2005; 29 (4): 469–471.
  18. Cubukcu A, Gonullu NN, Paksoy M, Alponat A, Kuru M, O¨zbay O. The role of obesity on the recurrence of pilonidal sinus disease in patients, who were treated by excision and Limberg flap transposition. Int J Colorectal Dis 2000; 15(3):173–175.
  19. Akinci OF, Bozer M, Uzunkoy A, Duzgun SA, Coşkun A. Incidence and aetiological factors in pilonidal sinus among Turkish soldiers. Eur J Surg 1999; 165:339–42.
  20. Bolandparvaz S, Moghadam Dizaj P, Salahi R, Paydar S, Bananzadeh M, Abbasi HR, et al. Evaluation of the risk factors of pilonidal sinus: a single center experience. Turk J Gastroenterol 2012;23:535–7.
  21. Serour F, Somekh E, Krutman B, et al. Excision with primary closure and suction drainage for pilonidal sinus in adolescent patients. Pediatr. Surg. Int. 2002;18:159–161.
  22. Baskom JU. Pilonidal disease: longterm results of follicle removal. Dis, Colon Rectum 1983;26:800–807.
  23. Karydakis GE. Easy and successful treatment of pilonidal sinus after explanation of its causative process. Aust. N. Z. J. Surg. 1992; 62:285–289.
  24. Patey D., Scarff R.W. Pathology of postanal pilonidal sinus it’s bearing on treatment, Lancet 1946; 248 (6423): 484–486.
  25. Doll, D. et al. Time and rate of sinus formation in pilonidal sinus disease. Int. J. Colorectal Dis. 23, 359–364.
  26. Ardelt, M. et al. Puberty is a major factor in pilonidal sinus disease: Gender-specific investigations of case number development in Germany from 2007 until 2015. Chirurg 88, 961–967.
  27. Yildiz t, Elmas B, Yucak A, Turgut H.T., Ilce Z. Risk factors for pilonidal sinus disease in teenagers, Indian J. Pediatr. 2017; 84 (2): 134–138.
  28. Fitzpatrick TB. The validity and practicality of sun-reactive skin types I through VI. Arch Dermatol. 1988; 124:869–71.
  29. Aldean I, Shankar PJ, Mathew J, Safarani N, Haboubi NY. Simple excision and primary closure of pilonidal sinus: a simple modification of conventional technique with excellent results. Colorectal Dis 2005;7(1):81–85.
  30. Levinson T, Sela T, Chencinski S, Derazne E, Tzur D, Elad H, et al. Pilonidal Sinus Disease: A 10-Year Review Reveals Occupational Risk Factors and the Superiority of the Minimal Surgery Trephine Technique. Mil Med. 2016; 181(4):389-94.
  31. Faraj FH, Baba HO, Salih AM, kakamad FH. Risk factors of pilonidal sinus disease in preparatory school students; a case control study. Ann Med Surg. 2020; 57:46-48.
  32. ML Price WAD Griffiths (1985) ArticleTitleNormal body hair: a review Clin. Exp. Dermatol 10 87–97 Occurrence Handle3884194.
  33. Comaish JS. The thyroid and hair growth. Semin Dermatol 1985; 4: 4–8.
  34. Blok GJ, de Boer LJ, van der Veen EA. Growth Hormone substitution in adult growth hormone-deficient men augments androgen effects on the skin. Clin Endocrinol 1997; 47: 29–36.
  35. Azziz R, Carmina E, Sawaya ME. Idiopathic hirsutism. Endocr Rev 2000; 21: 347–62.
  36. Rook/Wilkinson, Textbook of Dermatology, 5th edition 1992, Blackwell scientific publication, 1745-1762.
  37. Lunniss PJ, Jenkins PJ, Besser GM, Perry LA, Phillips RK. Gender differences in incidens of fistula-inano are not explained by circulating sex hormones. Int J Colorectal Dis 1995; 10: 25–8. 
آمار
تعداد مشاهده مقاله: 282
تعداد دریافت فایل اصل مقاله: 389


سامانه مدیریت نشریات علمی. قدرت گرفته از سیناوب