LinkedIn

 آمار

تعداد نشریات20
تعداد شماره‌ها1,089
تعداد مقالات9,995
تعداد مشاهده مقاله26,422,589
تعداد دریافت فایل اصل مقاله7,284,934
Jamali, Mohammad, Bigdeli, Farhad, Taheri, Reza, Saffarrian, Arash, Rahmanian, Abdolkarim, Eghbal, Keyvan, Ghahramani, Sulmaz. (1401). Surgical Outcome of Pediatric Posterior Fossa Tumors in Shiraz, Southern Iran: A Brief Report. سامانه مدیریت نشریات علمی, 47(6), 603-607. doi: 10.30476/ijms.2022.93334.2466
Mohammad Jamali; Farhad Bigdeli; Reza Taheri; Arash Saffarrian; Abdolkarim Rahmanian; Keyvan Eghbal; Sulmaz Ghahramani. "Surgical Outcome of Pediatric Posterior Fossa Tumors in Shiraz, Southern Iran: A Brief Report". سامانه مدیریت نشریات علمی, 47, 6, 1401, 603-607. doi: 10.30476/ijms.2022.93334.2466
Jamali, Mohammad, Bigdeli, Farhad, Taheri, Reza, Saffarrian, Arash, Rahmanian, Abdolkarim, Eghbal, Keyvan, Ghahramani, Sulmaz. (1401). 'Surgical Outcome of Pediatric Posterior Fossa Tumors in Shiraz, Southern Iran: A Brief Report', سامانه مدیریت نشریات علمی, 47(6), pp. 603-607. doi: 10.30476/ijms.2022.93334.2466
Jamali, Mohammad, Bigdeli, Farhad, Taheri, Reza, Saffarrian, Arash, Rahmanian, Abdolkarim, Eghbal, Keyvan, Ghahramani, Sulmaz. Surgical Outcome of Pediatric Posterior Fossa Tumors in Shiraz, Southern Iran: A Brief Report. سامانه مدیریت نشریات علمی, 1401; 47(6): 603-607. doi: 10.30476/ijms.2022.93334.2466

Surgical Outcome of Pediatric Posterior Fossa Tumors in Shiraz, Southern Iran: A Brief Report

Iranian Journal of Medical Sciences
مقاله 12، دوره 47، شماره 6، بهمن 2022، صفحه 603-607    اصل مقاله (285.35 K)
نوع مقاله: Brief Report(s)
شناسه دیجیتال (DOI): 10.30476/ijms.2022.93334.2466
نویسندگان
Mohammad Jamali1؛ Farhad Bigdeli1؛ Reza Taheri1؛ Arash Saffarrian1؛ Abdolkarim Rahmanian1؛ Keyvan Eghbal1؛ Sulmaz Ghahramani* 2
1Department of Neurosurgery, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
2Health Policy Research Center, Institute of Health, Shiraz University of Medical Sciences, Shiraz, Iran
چکیده
Posterior fossa tumors (PFTs) are prevalent in children, and about half of all childhood brain tumors arise from the structures of the posterior fossa. Studies on PFTs in Iranian children have mainly focused on epidemiological characteristics. This study aimed to evaluate surgical outcomes and predictive factors for survival in children with PFTs in Shiraz, Iran. A prospective cohort study was conducted from March 2014 to September 2019 in Namazi Hospital affiliated with Shiraz University of Medical Sciences (Shiraz, Iran). A total of 87 pediatric patients under the age of 16 who were diagnosed with PFT and had undergone surgery were recruited. The children were followed up for postoperative outcomes such as mortality and neurological complications. Data were analyzed using SPSS software (version 20.0) and R software (version 3.3.1). P<0.05 was considered statistically significant. The mean age of the patients was 6.49±4.14 years and 64.4% were male. Sixteen patients were lost to follow-up, 31 died after surgery, and 40 were in remission during phone calls. The median survival time of the patients was four years. The most common type of PFT was medulloblastoma (n=46, 53%). The result of the multivariate Cox proportional hazards model showed that age (P=0.034) was correlated with postoperative survival, hazard ratio 0.90 (95% confidence interval 0.82 to 0.99). Among various predictive factors, lower age was associated with poor outcomes in pediatric children with PFTs.
کلیدواژه‌ها
Brain neoplasms؛ Child؛ Medulloblastoma؛ Survival rate؛ Iran
سایر فایل های مرتبط با مقاله
مراجع
  1. Pollack IF, Jakacki RI. Childhood brain tumors: epidemiology, current management and future directions. Nat Rev Neurol. 2011;7:495-506. doi: 10.1038/nrneurol.2011.110. PubMed PMID: 21788981.
  2. Tabatabaei SM, Seddighi A, Seddighi AS. Posterior fossa tumor in children. Iranian Journal of Child Neurology. 2012;6:19-24. 
  3. Rahmanian A, Rakei SM, Mehrabani G. Prevalence of Medulloblastoma in Shiraz, Southern Iran. Middle East Journal of Cancer. 2013;4:135-6. 
  4. Stensvold E, Myklebust TA, Cappelen J, Due-Tonnessen BJ, Due-Tonnessen P, Kepka A, et al. Children treated for medulloblastoma and supratentorial primitive neuroectodermal tumor in Norway from 1974 through 2013: Unexplainable regional differences in survival. Pediatr Blood Cancer. 2019;66:e27910. doi: 10.1002/pbc.27910. PubMed PMID: 31264356. 
  5. Palmer SL, Glass JO, Li Y, Ogg R, Qaddoumi I, Armstrong GT, et al. White matter integrity is associated with cognitive processing in patients treated for a posterior fossa brain tumor. Neuro Oncol. 2012;14:1185-93. doi: 10.1093/neuonc/nos154. PubMed PMID: 22898373; PubMed Central PMCID: PMCPMC3424215.
  6. Zali A, Farzan A, Ramandi M. Prevalence of Childhood Brain Tumors at MOPHID hospital in Tehran (1996-2002). Journal of Medical Council. 2006;24:119-22. Persian.
  7. Kakar J, Ashraf J, Khan AA, Imran M, Rehmani MA, Ghori SA, et al. The Satisfactory Surgical Outcome of Posterior Fossa Brain Tumors in Children at Civil Hospital, Karachi. Asian J Neurosurg. 2020;15:377-81. doi: 10.4103/ajns.AJNS_56_19. PubMed PMID: 32656135; PubMed Central PMCID: PMCPMC7335127.
  8. Lanphear J, Sarnaik S. Presenting symptoms of pediatric brain tumors diagnosed in the emergency department. Pediatr Emerg Care. 2014;30:77-80. doi: 10.1097/PEC.0000000000000074. PubMed PMID: 24457493.
  9. Jenkin D, Shabanah MA, Shail EA, Gray A, Hassounah M, Khafaga Y, et al. Prognostic factors for medulloblastoma. Int J Radiat Oncol Biol Phys. 2000;47:573-84. doi: 10.1016/s0360-3016(00)00431-4. PubMed PMID: 10837938. 
  10. Figarella-Branger D, Civatte M, Bouvier-Labit C, Gouvernet J, Gambarelli D, Gentet JC, et al. Prognostic factors in intracranial ependymomas in children. J Neurosurg. 2000;93:605-13. doi: 10.3171/jns.2000.93.4.0605. PubMed PMID: 11014538.
  11. Desai KI, Nadkarni TD, Muzumdar DP, Goel A. Prognostic factors for cerebellar astrocytomas in children: a study of 102 cases. Pediatr Neurosurg. 2001;35:311-7. doi: 10.1159/000050443. PubMed PMID: 11786699.
  12. Butt B, Shiekh MM, Anwar H, Chudary MA, Butt RM. Six months Analysis of Posterior Fossa Surgery in Neurosurgery Unit-I, Punjab Institute of Neurosciences (PINS). Pakistan Journal of Neurological Surgery. 2018;22:7-16. 
آمار
تعداد مشاهده مقاله: 1,028
تعداد دریافت فایل اصل مقاله: 1,243


سامانه مدیریت نشریات علمی. قدرت گرفته از سیناوب