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Sheta, Heba, Abd El hafez, Amal, Harb, Dina, Zuhdy, Mohammad, Elzahaby, Islam. (1401). A Rare Entity: Papillary Thyroid Carcinoma with Squamous Differentiation Diagnosed in a Middle-aged Man Following Endoscopic Total Thyroidectomy via Axillo-Bilateral Breast Approach. سامانه مدیریت نشریات علمی, 14(1), 170-175. doi: 10.30476/mejc.2022.90671.1587
Heba Sheta; Amal Abd El hafez; Dina Harb; Mohammad Zuhdy; Islam A. Elzahaby. "A Rare Entity: Papillary Thyroid Carcinoma with Squamous Differentiation Diagnosed in a Middle-aged Man Following Endoscopic Total Thyroidectomy via Axillo-Bilateral Breast Approach". سامانه مدیریت نشریات علمی, 14, 1, 1401, 170-175. doi: 10.30476/mejc.2022.90671.1587
Sheta, Heba, Abd El hafez, Amal, Harb, Dina, Zuhdy, Mohammad, Elzahaby, Islam. (1401). 'A Rare Entity: Papillary Thyroid Carcinoma with Squamous Differentiation Diagnosed in a Middle-aged Man Following Endoscopic Total Thyroidectomy via Axillo-Bilateral Breast Approach', سامانه مدیریت نشریات علمی, 14(1), pp. 170-175. doi: 10.30476/mejc.2022.90671.1587
Sheta, Heba, Abd El hafez, Amal, Harb, Dina, Zuhdy, Mohammad, Elzahaby, Islam. A Rare Entity: Papillary Thyroid Carcinoma with Squamous Differentiation Diagnosed in a Middle-aged Man Following Endoscopic Total Thyroidectomy via Axillo-Bilateral Breast Approach. سامانه مدیریت نشریات علمی, 1401; 14(1): 170-175. doi: 10.30476/mejc.2022.90671.1587

A Rare Entity: Papillary Thyroid Carcinoma with Squamous Differentiation Diagnosed in a Middle-aged Man Following Endoscopic Total Thyroidectomy via Axillo-Bilateral Breast Approach

Middle East Journal of Cancer
مقاله 18، دوره 14، شماره 1 - شماره پیاپی 53، فروردین 2023، صفحه 170-175    اصل مقاله (4.88 M)
نوع مقاله: Case Report(s)
شناسه دیجیتال (DOI): 10.30476/mejc.2022.90671.1587
نویسندگان
Heba Sheta1؛ Amal Abd El hafez* 1، 2؛ Dina Harb3؛ Mohammad Zuhdy4؛ Islam A. Elzahaby4
1Pathology Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt
2Faculty of Medicine, Horus University - Egypt (HUE), New Damietta, Damietta, Egypt
3Diagnostic and Interventional Radiology Department, Faculty of Medicine, Mansoura University, Mansoura, Egypt
4Surgical Oncology Department, Oncology Center Mansoura University (OCMU), Faculty of Medicine, Mansoura University, Mansoura, Egypt
چکیده
Although squamous metaplasia is a well-known occurrence in papillary thyroid carcinoma (PTC), it is extremely uncommon to diagnose a PTC with squamous differentiation (PTC-SD), especially in a non-elderly patient, thus raising a diagnostic challenge when considering its broad histopathological differential diagnosis. Endoscopic thyroidectomy via axillo-bilateral breast approach (ABBA) has been recently validated as an appropriate surgical alternative to conventional thyroidectomy for treating PTC in the selected patients. Hereby, we report a rare case of PTC-SD diagnosed in a solitary thyroid nodule (STN) in a 30-year-old man with a family history of thyroid cancer who was operated using the endoscopic ABBA. In fact, detection of the squamous cell carcinoma component may not be feasible through fine needle aspiration cytology or frozen section examinations, while permanent paraffin sections and immunohistochemistry (if required) usually allows for its identification. Due to their diverse clinical and biological behaviors, it is important to differentiate PTC-SD from other conditions in which a thyroid specimen contains a squamous epithelium. PTCSD patients with favorable clinicopathological criteria as young age and localized disease can be fortunate candidates for the minimally invasive thyroidectomy approaches as endoscopic ABBA.
کلیدواژه‌ها
Papillary thyroid carcinoma؛ Squamous؛ Axillo-bilateral breast approach؛ Endoscopic thyroidectomy؛ Differential diagnosis
مراجع
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  7. Kim SK, Kang SY, Youn HJ, Jung SH. Comparison of conventional thyroidectomy and endoscopic thyroidectomy via axillo-bilateral breast approach in papillary thyroid carcinoma patients. Surg Endosc. 2016;30(8):3419-25. doi: 10.1007/s00464-015-4624- 9.
  8. Wirth U, von Ahnen T, Hampel J, Schardey J, Busch P, Schardey HM, et al. Quality of life and surgical outcome of ABBA versus EndoCATS endoscopic thyroid surgery: a single center experience. Surg Endosc. 2022;36:968-79. doi: 10.1007/ s00464-021- 08361-w.
  9. Lam AK. Squamous cell carcinoma of thyroid: a unique type of cancer in World Health Organization Classification. Endocr Relat Cancer. 2020;27(6):R177- R192. doi: 10.1530/ERC-20-0045.
  10. Limberg J, Ullmann TM, Stefanova D, Finnerty BM, Beninato T, Fahey TJ 3rd, et al. Prognostic characteristics of primary squamous cell carcinoma of the thyroid: A national cancer database analysis. World J Surg. 2020;44(2):348-55. doi: 10.1007/s00268-019- 05098-5.
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