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Spiny Hyperkeratosis-Like Follicular Mycosis Fungoides: A Case Report | ||
Middle East Journal of Cancer | ||
مقاله 28، دوره 14، شماره 3 - شماره پیاپی 55، مهر 2023، صفحه 457-462 اصل مقاله (6.89 M) | ||
نوع مقاله: Case Report(s) | ||
شناسه دیجیتال (DOI): 10.30476/mejc.2022.94274.1719 | ||
نویسندگان | ||
Shatila Torabi؛ Sara Fakhraei؛ Naser Tayebi Meibodi؛ Farnaz Ahmadpour* | ||
Cutaneous Leishmaniasis Research Center, Mashhad University of Medical Sciences, Mashhad, Iran | ||
چکیده | ||
Folliculotropic mycosis fungoides (FMF) is a rare variant of cutaneous T-cell lymphoma which is categorized as a separate entity. In histopathology, malignant lymphocytes selectively surround and infiltrate hair follicles. FMF has different clinical features in comparison with classic MF which is more refractory to treatment and has a worse prognosis. In the current study, we describe a 42-year-old patient presenting as follicular papules with keratotic spines and alopecia on the scalp, face, and trunk. Histologic examination of the patient’s biopsy revealed follicular and perifollicular T lymphoid cell infiltration without follicular mucinosis. Clonality analysis was interpreted as CD4+ T cell lymphoproliferative disorder. With the final diagnosis of FMF, the patient underwent treatment with oral acitretin and topical corticosteroid and psoralen plus ultraviolet A (PUVA). This case, in addition to the accompanied review of literature, revealed the importance of considering FMF in spiny hyperkeratotic papules in seborrheic areas refractory to antifungal treatments. | ||
کلیدواژهها | ||
Mycosis fungoides؛ Follicular؛ Lymphoma؛ Lymphoid cell؛ Alopecia | ||
اصل مقاله | ||
Shatila Torabi (Google Scholar) Farnaz Ahmadpour (PubMed) | ||
مراجع | ||
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