Mahur, Mamta, Singh, Munendra, Gurjar, Om Prakash, Semwal, Manoj Kumar. (1401). Assessment of Surface and Build-up Doses for a 6 MV Photon Beam using Parallel Plate Chamber, EBT3 Gafchromic Films, and PRIMO Monte Carlo Simulation Code. سامانه مدیریت نشریات علمی, 12(5), 455-464. doi: 10.31661/jbpe.v0i0.2101-1274
Mamta Mahur; Munendra Singh; Om Prakash Gurjar; Manoj Kumar Semwal. "Assessment of Surface and Build-up Doses for a 6 MV Photon Beam using Parallel Plate Chamber, EBT3 Gafchromic Films, and PRIMO Monte Carlo Simulation Code". سامانه مدیریت نشریات علمی, 12, 5, 1401, 455-464. doi: 10.31661/jbpe.v0i0.2101-1274
Mahur, Mamta, Singh, Munendra, Gurjar, Om Prakash, Semwal, Manoj Kumar. (1401). 'Assessment of Surface and Build-up Doses for a 6 MV Photon Beam using Parallel Plate Chamber, EBT3 Gafchromic Films, and PRIMO Monte Carlo Simulation Code', سامانه مدیریت نشریات علمی, 12(5), pp. 455-464. doi: 10.31661/jbpe.v0i0.2101-1274
Mahur, Mamta, Singh, Munendra, Gurjar, Om Prakash, Semwal, Manoj Kumar. Assessment of Surface and Build-up Doses for a 6 MV Photon Beam using Parallel Plate Chamber, EBT3 Gafchromic Films, and PRIMO Monte Carlo Simulation Code. سامانه مدیریت نشریات علمی, 1401; 12(5): 455-464. doi: 10.31661/jbpe.v0i0.2101-1274
Assessment of Surface and Build-up Doses for a 6 MV Photon Beam using Parallel Plate Chamber, EBT3 Gafchromic Films, and PRIMO Monte Carlo Simulation Code
1MSc, Department of Radiation Oncology, Delhi State Cancer Institute, Dilshad Garden, Delhi, India
2MSc, Department of Physics, School of Basic Sciences and Research, Sharda University, Greater Noida, Uttar Pradesh, India
3PhD, Department of Physics, School of Basic Sciences and Research, Sharda University, Greater Noida, Uttar Pradesh, India
4PhD, Government Cancer Hospital, Mahatma Gandhi Memorial Medical College, Indore-452001, India
5PhD, Department of Radiation Oncology, Army Hospital (Research & Referral), Delhi Cantonment New Delhi-110010, India
چکیده
Background: Accurate assessment of surface and build-up doses has a key role in radiotherapy, especially for the superficial lesions with uncertainties involved while performing measurements in the build-up region. Objective: This study aimed to assess surface and build-up doses for 6 MV photon beam from linear accelerator using parallel plate ionization chamber, EBT3 Gafchromic films, and PRIMO Monte Carlo (MC) simulation code. Material and Methods: In this experimental study, parallel plate chamber (PPC05) and EBT3 Gafchromic films were used to measure doses in a build-up region for 6 MV beam from the linear accelerator for different field sizes at various depths ranging from 0 to 2 cm from the surface with 100 cm source to surface distance (SSD) in a solid water phantom. Measured results were compared with Monte Carlo simulated results using PENELOPE-based PRIMO simulation code for the same setup conditions. Effect of gantry angle incidence and SSD were also analyzed for depth doses at the surface and build-up regions using PPC05 ion chamber and EBT3 Gafchromic films. Results: Doses measured at the surface were 14.78%, 19.87%, 25.83%, and 31.54% for field sizes of 5×5, 10×10, 15×15, and 20×20 cm2, respectively for a 6 MV photon beam with a parallel plate chamber and 14.20%, 19.14%, 25.149%, and 30.90%, respectively for EBT3 Gafchromic films. Both measurement sets were in good agreement with corresponding simulated results from the PRIMO MC simulation code; doses increase with the increase in field sizes. Conclusion: Good agreement was observed between the measured depth doses using parallel plate ionization chamber, EBT3 Gafchromic films, and the simulated depth doses using PRIMO Monte Carlo simulation code.
Kim S, Liu CR, Zhu TC, Palta JR. Photon beam skin dose analyses for different clinical setups. Med Phys. 1998;25(6):860-6. doi: 10.1118/1.598261. PubMed PMID: 9650173.
Nilsson B, Brahme A. Absorbed dose from secondary electrons in high energy photon beams. Phys Med Biol. 1979;24(5):901-12. doi: 10.1088/0031-9155/24/5/003. PubMed PMID: 117462.
Biggs PJ, Ling CC. Electrons as the cause of the observed dmax shift with field size in high energy photon beams. Med Phys. 1979;6(4):291-5. doi: 10.1118/1.594580. PubMed PMID: 113656.
ICRP Publication 59. The biological basis for dose limitation in the skin. A report of a Task Group of Committee 1 of the International Commission on Radiological Protection. Ann ICRP. 1991;22(2):1-104. PubMed PMID: 1812796.
International Commission on Radiation Units and Measurements. Determination of dose equivalents resulting from external radiation sources. ICRU Report 39; Washington DC: ICRU; 2020.
Devic S, Seuntjens J, Abdel-Rahman W, Evans M, Olivares M, Podgorsak EB, Vuong T, Soares CG. Accurate skin dose measurements using radiochromic film in clinical applications. Med Phys. 2006;33(4):1116-24. doi: 10.1118/1.2179169. PubMed PMID: 16696489.
Velkley DE, Manson DJ, Purdy JA, Oliver GD Jr. Build-up region of megavoltage photon radiation sources. Med Phys. 1975;2(1):14-9. doi: 10.1118/1.594158. PubMed PMID: 805358.
O’Shea E, McCavana P. Review of surface dose detectors in radiotherapy. Journal of Radiotherapy in Practice. 2003;3(2):69-76. doi: 10.1017/S1460396903000049.
Gerbi BJ, Khan FM. Measurement of dose in the buildup region using fixed-separation plane-parallel ionization chambers. Med Phys. 1990;17(1):17-26. doi: 10.1118/1.596522. PubMed PMID: 2106611.
Nahum AE. Condensed-history Monte-Carlo simulation for charged particles: what can it do for us? Radiat Environ Biophys. 1999;38(3):163-73. doi: 10.1007/s004110050152. PubMed PMID: 10525953.
Abdel-Rahman W, Seuntjens JP, Verhaegen F, Deblois F, Podgorsak EB. Validation of Monte Carlo calculated surface doses for megavoltage photon beams. Med Phys. 2005;32(1):286-98. doi: 10.1118/1.1829401. PubMed PMID: 15719980.
Kim JH, Hill R, Kuncic Z. Practical considerations for reporting surface dose in external beam radiotherapy: a 6 MV X-ray beam study. Australas Phys Eng Sci Med. 2012;35(3):271-82. doi: 10.1007/s13246-012-0145-1. PubMed PMID: 22736310.
Apipunyasopon L, Srisatit S, Phaisangittisakul N. An investigation of the depth dose in the build-up region, and surface dose for a 6-MV therapeutic photon beam: Monte Carlo simulation and measurements. J Radiat Res. 2013;54(2):374-82. doi: 10.1093/jrr/rrs097. PubMed PMID: 23104898. PubMed PMCID: PMC3589935.
Bilge H, Cakir A, Okutan M, Acar H. Surface dose measurements with GafChromic EBT film for 6 and 18MV photon beams. Phys Med. 2009;25(2):101-4. doi: 10.1016/j.ejmp.2008.05.001. PubMed PMID: 18571964.
Gafchromic Radiotherapy Films. Ashland, KY: Ashland; 2022. Available from: http://www.ashland.com/products/gafchromicradiotherapyfilms.
Menegotti L, Delana A, Martignano A. Radiochromic film dosimetry with flatbed scanners: a fast and accurate method for dose calibration and uniformity correction with single film exposure. Med Phys. 2008;35(7):3078-85. doi: 10.1118/1.2936334. PubMed PMID: 18697531.
Rodriguez M, Sempau J, Brualla L. PRIMO: a graphical environment for the Monte Carlo simulation of Varian and Elekta linacs. Strahlenther Onkol. 2013;189(10):881-6. doi: 10.1007/s00066-013-0415-1. PubMed PMID: 24005581.
Brualla L, Rodríguez M, Sempau J. PRIMO User’s Manual Version 0.3.1.1770. Strahlenklinik, Hufelandstrasse; 2018. p. 55.
Bacala AM. Linac photon beam fine-tuning in PRIMO using the gamma-index analysis toolkit. Radiat Oncol. 2020;15(1):8. doi: 10.1186/s13014-019-1455-1. PubMed PMID: 31906977. PubMed PMCID: PMC6945657.
Sempau J, Sánchez-Reyes A, Salvat F, ben Tahar HO, Jiang SB, Fernández-Varea JM. Monte Carlo simulation of electron beams from an accelerator head using PENELOPE. Phys Med Biol. 2001;46(4):1163-86. doi: 10.1088/0031-9155/46/4/318. PubMed PMID: 11324958.
Brualla L, Salvat F, Palanco-Zamora R. Efficient Monte Carlo simulation of multileaf collimators using geometry-related variance-reduction techniques. Phys Med Biol. 2009;54(13):4131-49. doi: 10.1088/0031-9155/54/13/011 PubMed PMID: 19521002.
Rodriguez M, Sempau J, Brualla L. A combined approach of variance-reduction techniques for the efficient Monte Carlo simulation of linacs. Phys Med Biol. 2012;57(10):3013-24. doi: 10.1088/0031-9155/57/10/3013. PubMed PMID: 22538321.
Brualla L, Rodriguez M, Lallena AM. Monte Carlo systems used for treatment planning and dose verification. Strahlenther Onkol. 2017;193(4):243-259. doi: 10.1007/s00066-016-1075-8. PubMed PMID: 27888282.
Belosi MF, Rodriguez M, Fogliata A, Cozzi L, Sempau J, et al. Monte Carlo simulation of TrueBeam flattening-filter-free beams using varian phase-space files: comparison with experimental data. Med Phys. 2014;41(5):051707. doi: 10.1118/1.4871041. PubMed PMID: 24784373.
Hermida-López M, Sánchez-Artuñedo D, Calvo-Ortega JF. PRIMO Monte Carlo software benchmarked against a reference dosimetry dataset for 6 MV photon beams from Varian linacs. Radiat Oncol. 2018;13(1):144. doi: 10.1186/s13014-018-1076-0. PubMed PMID: 30086767. PubMed PMCID: PMC6081807.
Jong WL, Wong JH, Ung NM, Ng KH, Ho GF, Cutajar DL, Rosenfeld AB. Characterization of MOSkin detector for in vivo skin dose measurement during megavoltage radiotherapy. J Appl Clin Med Phys. 2014;15(5):4869. doi: 10.1120/jacmp.v15i5.4869. PubMed PMID: 25207573. PubMed PMCID: PMC5711095.
Qi ZY, Deng XW, Huang SM, Zhang L, He ZC, Li XA, Kwan I, Lerch M, Cutajar D, Metcalfe P, Rosenfeld A. In vivo verification of superficial dose for head and neck treatments using intensity-modulated techniques. Med Phys. 2009;36(1):59-70. doi: 10.1118/1.3030951. PubMed PMID: 19235374.
Yu PK, Cheung T, Butson MJ. Variations in skin dose using 6MV or 18MV x-ray beams. Australas Phys Eng Sci Med. 2003;26(2):79-81. PubMed PMID: 12956189.
Jackson W. Surface effects of high-energy X rays at oblique incidence. Br J Radiol. 1971;44(518):109-15. doi: 10.1259/0007-1285-44-518-109. PubMed PMID: 4994161.
Yadav G, Yadav RS, Kumar A. Skin dose estimation for various beam modifiers and source-to-surface distances for 6MV photons. J Med Phys. 2009;34(2):87-92. doi: 10.4103/0971-6203.51935. PubMed PMID: 20098542. PubMed PMCID: PMC2805895.
Butson MJ, Cheung T, Yu PK. Variations in 6MV x-ray radiotherapy build-up dose with treatment distance. Australas Phys Eng Sci Med. 2003;26(2):88-90. PubMed PMID: 12956192.