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Berbari, Roula, Nassif, Nahla, Sfeir, Elia. (1401). Inflammatory Status of Excavated Pulp Tissue and Internal Root Resorption in Pulpotomized Primary Molars. سامانه مدیریت نشریات علمی, 23(3), 284-291. doi: 10.30476/dentjods.2021.88927.1374
Roula Farid Berbari; Nahla Fayez Nassif; Elia Michel Sfeir. "Inflammatory Status of Excavated Pulp Tissue and Internal Root Resorption in Pulpotomized Primary Molars". سامانه مدیریت نشریات علمی, 23, 3, 1401, 284-291. doi: 10.30476/dentjods.2021.88927.1374
Berbari, Roula, Nassif, Nahla, Sfeir, Elia. (1401). 'Inflammatory Status of Excavated Pulp Tissue and Internal Root Resorption in Pulpotomized Primary Molars', سامانه مدیریت نشریات علمی, 23(3), pp. 284-291. doi: 10.30476/dentjods.2021.88927.1374
Berbari, Roula, Nassif, Nahla, Sfeir, Elia. Inflammatory Status of Excavated Pulp Tissue and Internal Root Resorption in Pulpotomized Primary Molars. سامانه مدیریت نشریات علمی, 1401; 23(3): 284-291. doi: 10.30476/dentjods.2021.88927.1374

Inflammatory Status of Excavated Pulp Tissue and Internal Root Resorption in Pulpotomized Primary Molars

Journal of Dentistry
مقاله 6، دوره 23، شماره 3 - شماره پیاپی 76، آذر 2022، صفحه 284-291    اصل مقاله (508.72 K)
نوع مقاله: Original Article
شناسه دیجیتال (DOI): 10.30476/dentjods.2021.88927.1374
نویسندگان
Roula Farid Berbari* ؛ Nahla Fayez Nassif؛ Elia Michel Sfeir
Dept. of Pediatric Dentistry and Public Health, Faculty of Dental Medicine, Lebanese University, Beirut, Lebanon.
چکیده
Statement of the Problem: Internal root resorption after pulpotomy is a pathological phenomenon and can lead to early root resorption and subsequent loss of the tooth.
Purpose: To assess the relationship between initial inflammatory coronal pulp status in decayed primary molars treated by pulpotomy and internal root resorption after one-year follow-up.
Materials and Method: In this clinical in vivo and in vitro experiment, vital pulpotomies were performed on 50 primary molars from 50 patients aged 5 to 10 years. Coronal pulp was carefully removed followed by hemostasis and placement of a reinforced zinc oxide eugenol over the vital radicular pulp. Enzyme-linked immunosorbent assay (ELISA) assay was done on coronal pulp samples and the level of tumor necrosis factor-alpha (TNF- α) and interlukin-6 (IL-6) was measured. After a 12-month follow-up, periapical radiographs were taken from pulpotomized teeth. Kolmogorov-Smirnov, Chi-square, Kruskal–Wallis, and Mann-Whitney tests were implemented.
Results: 11 treated teeth (22%) showed an internal root resorption as diagnosed on X-rays. No significant association was found between TNF- α, IL-6 levels, and pathological root resorption respectively (p= 0.953) and (p= 0.944). A significant association between age and pathological root resorption was observed (p= 0.031). No significant association between remaining dentin thickness and pathological root resorption was established (p= 0.346).
Conclusion: There was no association between pro-inflammatory cytokines levels/ TNF- α, IL-6 and internal root resorption following pulpotomy in pediatric patients.
کلیدواژه‌ها
Cytokines؛ Internal root resorption؛ Pulpotomy؛ Primary molars؛ Caries
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