1Radiology Center, Bach Mai Hospital, Hanoi City, Vietnam
2Radiology Department, Ha Noi Medical University, Hanoi City, Vietnam
3Radiology Department, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam
4Radiology Department, National Children Hospital, Hanoi, Vietnam
چکیده
Background: The present study aimed to present computed tomography (CT) scan characteristics of different mediastinal masses in children to correlate CT findings of the mediastinal masses with histopathology; we also sought to differentiate between benign and malignant mediastinal mass lesions based on CT findings. Method: This prospective cohort study analyzed 60 patients who underwent multi-slice CT scan for characterization of mediastinal mass. Subsequently, imaging findings were verified with pathological diagnosis. Results: The median age of the patients was 5.3 years. The common symptoms among these patients were cough, dyspnea, chest pain, and fever. There were 24 benign (40%) and 36 (60%) malignant cases. According to their origins, 20 (33.3%) presented as neurogenic tumors, 16 (26.7%) as lymphomas, (15%) as germ cell tumors 9, and the remaining 15 (25%) as tumors: thymic pathologies, lymphangiomas, and bronchogenic cyst. 22 (36.7%) tumors were located in the posterior mediastinum, followed by 21 (35%) in the anterior mediastinum and 11 (18.3%) in the middle mediastinum. Conclusion: CT scan was found to be able to distinguish specific tissue densities and their ability to display mediastinum in axial plane. Reconstruction in sagital and coronal planes makes it a useful technique for the evaluation of a mediastinal mass.
Anh TT, Quang HH, Khac HB. Validity of multi-slice computed tomography in evaluation of mediastinal mass lesions. Middle East J Cancer. 2022;13(3):515-22. doi: 10.30476/mejc.2022.88115.1458.
مراجع
Pandey S, Jaipal U, Mannan N, Yadav R. Diagnostic accuracy of multidetector computed tomography scan in mediastinal masses assuming histopathological findings as gold standard. Pol J Radiol. 2018;83:e234-e242. doi: 10.5114/pjr.2018.76709.
Pulasani K, Narayanaswamy I, Ramprakash HV. Evaluation of Mediastinal Mass Lesions Using Multi-detector Row Computed Tomography and Correlation with Histopathological Diagnosis. Int. J. Sci. Study. 2015; 3(6):156-163. doi: 10.17354/ijss/2015/414.
Dixit R, Shah NS, Goyal M, Patil CB, Panjabi M, Gupta RC, et al. Diagnostic evaluation of mediastinal lesions: Analysis of 144 cases. Lung India. 2017;34(4):341-8. doi: 10.4103/lungindia.lungindia_311_16.
Kemu A, Rashid N, Ahmad KK, Ali W. Diagnostic role of computed tomography in evaluation of mediastinal masses. Ann King Edw Med Univ. 2011; 17(4):410-5. doi: 10.21649/akemu.v17i4.574
Gun F, Erginel B, Unüvar A, Kebudi R, Salman T, Celik A. Mediastinal masses in children: experience with 120 cases. Pediatr Hematol Oncol. 2012;29(2):141-7. doi: 10.3109/08880018.2011.646385.
Grosfeld JL, Skinner MA, Rescorla FJ, West KW, Scherer LR 3rd. Mediastinal tumors in children: experience with 196 cases. Ann Surg Oncol. 1994;1(2):121-7. doi: 10.1007/BF02303555.
Duwe BV, Sterman DH, Musani AI. Tumors of the mediastinum. Chest. 2005;128(4):2893-909. doi: 10.1378/chest.128.4.2893.
McCarville MB. Malignant pulmonary and mediastinal tumors in children: differential diagnoses. Cancer Imaging. 2010;10 Spec no A(1A):S35-41. doi: 10.1102/1470-7330.2010.9015.
Arumugam V, Nazir H, Rajasekar KV. Multidetector computed tomography evaluation of mediastinal lesions with histopathological diagnosis. Open J Respir Dis.2015;5:55-62. doi: 10.4236/ojrd.2015.53006.
Almeida PT, Heller D. Anterior Mediastinal Mass. 2020 Aug 14. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020 Jan. PMID: 31536215.
Allen CE, Kelly KM, Bollard CM. Pediatric lymphomas and histiocytic disorders of childhood. Pediatr Clin North Am. 2015;62(1):139-65. doi: 10.1016/j.pcl.2014.09.010.
Tansel T, Onursal E, Dayloğlu E, Başaran M, Sungur Z, Qamci E, et al. Childhood mediastinal masses in infants and children. Turk J Pediatr. 2006;48(1):8-12.
Delacourt C, Mani TM, Bonnerot V, de Blic J, Sayeg N, Lallemand D, et al. Computed tomography with normal chest radiograph in tuberculous infection. Arch Dis Child. 1993;69(4):430-2. doi: 10.1136/adc.69.4.430.
Okamatsu C, London WB, Naranjo A, Hogarty MD, Gastier-Foster JM, Look AT, et al. Clinicopathological characteristics of ganglioneuroma and ganglioneuroblastoma: a report from the CCG and COG. Pediatr Blood Cancer. 2009;53(4):563-9. doi: 10.1002/pbc.22106.
Sundararajan S, Carter YM. Mediastinal Nonseminoma. 2020 Jun 25. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020 Jan–. PMID: 28613751.
Juanpere S, Cañete N, Ortuño P, Martínez S, Sanchez G, Bernado L. A diagnostic approach to the mediastinal masses. Insights Imaging. 2013;4(1):29-52. doi: 10.1007/s13244-012-0201-0.
