LinkedIn

 آمار

تعداد نشریات20
تعداد شماره‌ها1,089
تعداد مقالات9,995
تعداد مشاهده مقاله26,212,616
تعداد دریافت فایل اصل مقاله7,239,907
Wang, Zhi-Hui, Wu, Yue, Dai, Zi-Wei, Dong, Yuan-Yuan, Wang, Bin. (1400). Effects of Interleukin-10 -1082G/A and -592C/A Gene Polymorphisms on the Risk of Human Immunodeficiency Virus-1 Infection: An Updated Meta-analysis. سامانه مدیریت نشریات علمی, 19(1), 91-101. doi: 10.22034/iji.2022.81583.1541
Zhi-Hui Wang; Yue Wu; Zi-Wei Dai; Yuan-Yuan Dong; Bin Wang. "Effects of Interleukin-10 -1082G/A and -592C/A Gene Polymorphisms on the Risk of Human Immunodeficiency Virus-1 Infection: An Updated Meta-analysis". سامانه مدیریت نشریات علمی, 19, 1, 1400, 91-101. doi: 10.22034/iji.2022.81583.1541
Wang, Zhi-Hui, Wu, Yue, Dai, Zi-Wei, Dong, Yuan-Yuan, Wang, Bin. (1400). 'Effects of Interleukin-10 -1082G/A and -592C/A Gene Polymorphisms on the Risk of Human Immunodeficiency Virus-1 Infection: An Updated Meta-analysis', سامانه مدیریت نشریات علمی, 19(1), pp. 91-101. doi: 10.22034/iji.2022.81583.1541
Wang, Zhi-Hui, Wu, Yue, Dai, Zi-Wei, Dong, Yuan-Yuan, Wang, Bin. Effects of Interleukin-10 -1082G/A and -592C/A Gene Polymorphisms on the Risk of Human Immunodeficiency Virus-1 Infection: An Updated Meta-analysis. سامانه مدیریت نشریات علمی, 1400; 19(1): 91-101. doi: 10.22034/iji.2022.81583.1541

Effects of Interleukin-10 -1082G/A and -592C/A Gene Polymorphisms on the Risk of Human Immunodeficiency Virus-1 Infection: An Updated Meta-analysis

Iranian Journal of Immunology
دوره 19، شماره 1، خرداد 2022، صفحه 91-101    اصل مقاله (2.83 M)
نوع مقاله: Review Article
شناسه دیجیتال (DOI): 10.22034/iji.2022.81583.1541
نویسندگان
Zhi-Hui Wang1، 2؛ Yue Wu1، 2؛ Zi-Wei Dai1، 2؛ Yuan-Yuan Dong1، 2؛ Bin Wang* 1، 2
1Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, Anhui, P. R. China.
2Anhui Provincial Laboratory of Inflammatory and Immune Diseases, Anhui Medical University, Hefei, Anhui, P. R. China.
چکیده
This paper has aimed to review the available evidence on the association between Interleukin (IL) -10 -1082G/A, -592C/A gene polymorphisms and the risk of human immunodeficiency virus-1(HIV-1) infection. The data of PubMed updated in May 2021 were retrieved. The HIV infection risks were estimated in allelic, recessive, dominant, homozygous, heterozygous, over-dominant models of IL-10-1082G/A and-592C/A gene locus as odds ratio (OR) with the corresponding 95% confidence interval (95% CI). The correlation was not significant between -1082G/A polymorphism and HIV-1 susceptibility (allelic model (G vs. A: OR (95% CI)=0.968 (0.878-1.067)); recessive model (GG vs. AA+AG: OR (95% CI)=0.940, (0.771-1.146)); dominant model (GG+AG vs. AA: OR (95% CI)=0.967(0.846-1.106)); homozygous model (GG vs. AA: OR (95% CI)=0.971(0.780-1.209)); heterozygous model (AG vs. AA: OR (95% CI)=0.988(0.797-1.224)) and over-dominant model (GG+AA vs. AG: OR (95% CI)=0.969(0.781-1.201)). IL-10-592C/A polymorphism might be related to HIV-1 in allelic model, dominant model, homozygous model and heterozygous model (OR (95% CI)(0.796-0.965); OR (95% CI)=0.793(0.664-0.948); OR (95% CI)=0.755,(0.612-0.930); OR (95% CI)=0.820(0.679-0.991), respectively), but not to recessive model and over-dominant model (OR (95% CI)=0.882(0.770-1.010) and OR (95% CI)=1.009(0.897-1.148)).
کلیدواژه‌ها
HIV-1؛ Interleukin-10؛ Meta-analysis؛ Polymorphism؛ Susceptibility
آمار
تعداد مشاهده مقاله: 766
تعداد دریافت فایل اصل مقاله: 663


سامانه مدیریت نشریات علمی. قدرت گرفته از سیناوب