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Prevalence, Antimicrobial Susceptibility Profile, and the Associated Risk Factors of Uropathogenic E. coli among Pregnant Women in Zakho City, Kurdistan Region, Iraq | ||
| Women’s Health Bulletin | ||
| مقاله 5، دوره 9، شماره 1 - شماره پیاپی 32، فروردین 2022، صفحه 34-41 اصل مقاله (402.57 K) | ||
| نوع مقاله: Research Article | ||
| شناسه دیجیتال (DOI): 10.30476/whb.2022.93607.1154 | ||
| نویسندگان | ||
| Ilaf Jasim Mohammed1؛ Ibrahim Abdulqader Naqid* 2؛ Huseyin Kaya Süer1 | ||
| 1Department of Infectious Diseases and Clinical Microbiology, Nicosia, Near East University Hospital, Turkish Republic of North Cyprus, Turkey | ||
| 2Department of Biomedical science, College of Medicine, University of Zakho, Kurdistan Region, Iraq | ||
| چکیده | ||
| Background: Escherichia coli (E. coli) are known to be a major cause of uropathogen among women globally. Urinary tract infection in pregnant women continues to pose clinical problems, which is a big burden for physicians. The emergence of antibiotic resistance to E. coli is inevitable and one of the critical health-associated problems. The present study aimed to determine the E. coli isolates, risk factors, and antibiotic resistance profile of the UTI among pregnant women. Methods: We conducted this cross-sectional study on pregnant women who attended maternity hospital in Zakho City, Kurdistan Region, Iraq. From October 2020 to January 2021, 196 subjects were recruited in the present experiment. Uropathogenic E. coli were detected from mid-stream urine of the participants. Subsequently, we performed antibiotic sensitivity test using microbiological standard tests. Through the use of designed questionnaires, the required data were collected, processed, and analysed via the Fisher’s exact test and Chi-square. Results: Out of a total of 196 subjects, 34 (17.34%) were culture positive for E. coli infection among pregnant women. A high rate of infection was detected in the age group of between 25-34 years (21.6%). Additionally, the highest rate of E. coli belonged to illiterate people (19.4%), followed by those with higher education (18.9%). The assessment of the risk factors associated with E. coli indicated that diabetes (P=0.028), a history of UTI infection (P=0.049), and the presence of symptoms during infection (P=0.001) were statistically significantly different. The antibiotics sensitivity profile in urine samples of pregnant women showed that E. coli were extremely sensitive to Nitrofurantoin (82.4%), Meropenem (79.4%), and around 67.6% for both Amikacin and Ciprofloxacin. Conclusion: The prevalence rate of E. coli infection is quite lower among pregnant women compared to that in non-pregnant ones. The major risk factors associated with E. coli during pregnancy were diabetes mellitus, a history of UTI, and the presence of symptoms during infection. E. coli isolated from urine samples seem to be different concerning antibiotic sensitivity pattern. During their regular follow-up, pregnant women should also be examined for major risk factors and antibiotic susceptibility. | ||
| کلیدواژه‌ها | ||
| E. coli؛ Risk factors؛ Uropathogen؛ Antibiotic sensitivity؛ Pregnant women؛ Iraq | ||
| مراجع | ||
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1. Naqid IA, Balatay AA, Hussein NR, Saeed KA, Ahmed HA, Yousif SH. Antibiotic Susceptibility Pattern of Escherichia coli Isolated from Various Clinical Samples in Duhok City, Kurdistan Region of Iraq. Int J Infect. 2020;7:e103740. doi: 10.5812/iji.103740. ## 2. Assafi M, Ibrahim N, Hussein N, Taha A, Balatay A. Urinary Bacterial Profile and Antibiotic Susceptibility Pattern among Patients with Urinary Tract Infection in Duhok City, Kurdistan Region, Iraq. Int J Pure Appl Sci Technol. 2015;30:54-63. ## 3. Hussein NR, Daniel S, Salim K, Saleh Assafi M. Urinary Tract Infections and Antibiotic Sensitivity Patterns Among Women Referred to Azadi Teaching Hospital, Duhok, Iraq. Avicenna J Clin Microbiol Infect. 2018;5:27-30. doi: 10.34172/ajcmi.2018.05. ## 4. Naqid IA, Hussein NR, Balatay A, Saeed KA, Ahmed HA. Antibiotic Susceptibility Patterns of Uropathogens Isolated from Female Patients with Urinary Tract Infection in Duhok Province, Iraq. Jundishapur J Health Sci. 2020;12:e105146. doi: 10.5812/jjhs.105146. ## 5. Ipe DS, Sundac L, Benjamin WH, Jr., Moore KH, Ulett GC. Asymptomatic bacteriuria: prevalence rates of causal microorganisms, etiology of infection in different patient populations, and recent advances in molecular detection. FEMS Microbiol Lett. 2013;346:1-10. doi: 10.1111/1574-6968.12204. PubMed PMID: 23808987. ## 6. Masinde A, Gumodoka B, Kilonzo A, Mshana SE. Prevalence of urinary tract infection among pregnant women at Bugando Medical Centre, Mwanza, Tanzania. Tanzan J Health Res. 2009;11:154-9. doi: 10.4314/thrb.v11i3.47704. PubMed PMID: 20734713. ## 7. Giraldo PC, Araújo ED, Junior JE, do Amaral RLG, Passos MRL, Gonçalves AK. The prevalence of urogenital infections in pregnant women experiencing preterm and full-term labor. Infectious diseases in obstetrics and gynecology. 2012;2012:878241-. doi: 10.1155/2012/878241. PubMed PMID: 22505801. ## 8. Subramanian M, Ganesapandian S, Singh M, Kumaraguru A. Antimicrobial Susceptibility Pattern of Urinary Tract Infection Causing Human Pathogenic Bacteria. Asian J Med Sci. 2011;3. ## 9. Abat C, Desboves G, Olaitan AO, Chaudet H, Roattino N, Fournier PE, et al. Increasing burden of urinary tract infections due to intrinsic colistin-resistant bacteria in hospitals in Marseille, France. Int J Antimicrob Agents. 2015;45:144-50. doi: 10.1016/j.ijantimicag.2014.10.010. PubMed PMID: 25497970. ## 10. Abdulkareem W HN, Mohammed A, Arif S, Naqid I. Risk Factors Association for MRSA Nasal Colonization in Preoperative Patients in Azadi Teaching Hospital-Duhok, Kurdistan Region, Iraq. Science Journal of University of Zakho. 2020;8:88-91. doi: 10.25271/sjuoz.2020.8.3.712. ## 11. Livermore DM, Pearson A. Antibiotic resistance: location, location, location. Clin Microbiol Infect. 2007;13 Suppl 2:7-16. doi: 10.1111/j.1469-0691.2007.01724.x. PubMed PMID: 17488371. ## 12. Naqid IA, Hussein NR, Balatay AA, Saeed KA, Ahmed HA. The Antimicrobial Resistance Pattern of Klebsiella pneumonia Isolated from the Clinical Specimens in Duhok City in Kurdistan Region of Iraq. J Kermanshah Univ Med Sci. 2020;24:e106135. doi: 10.5812/jkums.106135. ## 13. Naqid IA, Balatay AA, Hussein NR, Ahmed HA, Saeed KA, Abdi SA. Bacterial Strains and Antimicrobial Susceptibility Patterns in Male Urinary Tract Infections in Duhok Province, Iraq. Middle East J Rehabil Health Stud. 2020;7:e103529. doi: 10.5812/mejrh.103529. ## 14. Shaheen H, Farahat T, El-Hakeem Hammad N. Prevalence of urinary tract infection among pregnant women and possible risk factors. Menoufia Medical Journal. 2016;29:1055-9. doi: 10.4103/1110-2098.202505. ## 15. Amin M, Mehdinejad M, Pourdangchi Z. Study of bacteria isolated from urinary tract infections and determination of their susceptibility to antibiotics. 2009;2:118-23. ## 16. Emiru T, Beyene G, Tsegaye W, Melaku S. Associated risk factors of urinary tract infection among pregnant women at Felege Hiwot Referral Hospital, Bahir Dar, North West Ethiopia. BMC research notes. 2013;6:292-. doi: 10.1186/1756-0500-6-292. PubMed PMID: 23885968. ## 17. Olsen BE, Hinderaker SG, Lie RT, Gasheka P, Baerheim A, Bergsjø P, et al. The diagnosis of urinary tract infections among pregnant women in rural Tanzania; prevalences and correspondence between different diagnostic methods. Acta Obstet Gynecol Scand. 2000;79:729-36. PubMed PMID: 10993095. ## 18. Al-Mukhtar S. Urinary Tract Infection Among Women Aged (18-40) Years Old inKirkuk City, Iraq. The Open Nursing Journal. 2019;12:248-54. doi: 10.2174/1874434601812010248. ## 19. Azami M, Jaafari Z, Masoumi M, Shohani M, Badfar G, Mahmudi L, et al. The etiology and prevalence of urinary tract infection and asymptomatic bacteriuria in pregnant women in Iran: a systematic review and Meta-analysis. BMC Urol. 2019;19:43. doi: 10.1186/s12894-019-0454-8. PubMed PMID: 31146773; PubMed Central PMCID: PMCPmc6543660. ## 20. Dimetry SR, El-Tokhy HM, Abdo NM, Ebrahim MA, Eissa M. Urinary tract infection and adverse outcome of pregnancy. J Egypt Public Health Assoc. 2007;82:203-18. PubMed PMID: 18410708. ## 21. Al-Jawadi A, editor Urinary Tract Infections Among Pregnant Women Attending Al-Batool Maternity Teaching Hospital2013. ## 22. Alhamdany MH. Antibiotic susceptibility of bacteria isolated from patients with diabetes mellitus and recurrent urinary tract infections in Babylon Province, Iraq. Medical Journal of Babylon. 2018;15:63-8. doi: 10.4103/mjbl.mjbl_16_18. ## 23. Byambasuren O, Cardona M, Bell K, Clark J, McLaws M-L, Glasziou P. Estimating the extent of asymptomatic COVID-19 and its potential for community transmission: systematic review and meta-analysis. medRxiv. 2020:2020.05.10.20097543. doi: 10.1101/2020.05.10.20097543. ## 24. Gunes G, Gunes A, Tekiner S, Karaoglu L, Kaya M, Pehlivan E. Bacteriuria and socioeconomic associations among pregnant women in Malatya, Turkey. Public Health. 2005;119:1039-41. doi: 10.1016/j.puhe.2004.11.007. PubMed PMID: 15913680. ## 25. Amiri M, Lavasani Z, Norouzirad R, Najibpour R, Mohamadpour M, Nikpoor AR, et al. Prevalence of Urinary Tract Infection Among Pregnant Women and its Complications in Their Newborns During the Birth in the Hospitals of Dezful City, Iran, 2012 - 2013. Iranian Red Crescent medical journal. 2015;17:e26946-e. doi: 10.5812/ircmj.26946. PubMed PMID: 26430526. ## 26. Haider G, Zehra N, Munir AA, Haider A. Risk factors of urinary tract infection in pregnancy. J Pak Med Assoc. 2010;60:213-6. PubMed PMID: 20225781. ## 27. Taye S, Getachew M, Desalegn Z, Biratu A, Mubashir K. Bacterial profile, antibiotic susceptibility pattern and associated factors among pregnant women with Urinary Tract Infection in Goba and Sinana Woredas, Bale Zone, Southeast Ethiopia. BMC Research Notes. 2018;11:799. doi: 10.1186/s13104-018-3910-8. ## 28. Adinortey C, Amewowor DHAK, Otwe E, Galyuon I, Asante DKA. Antibiotic Susceptibility Profile and Occurrence of Escherichia coli Isolated from Clinical and Environmental Samples in Cape Coast, Ghana. Research Journal of Microbiology. 2017;12:170-6. doi: 10.3923/jm.2017.170.176. ## | ||
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