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Babaei, Maryam, Kanannejad, Zahra, Sepahi, Najmeh, Alyasin, Soheila. (1400). The Effect of COVID-19 Pandemic on Patients with Primary Immunodeficiency: A Cohort Study. سامانه مدیریت نشریات علمی, 47(2), 162-166. doi: 10.30476/ijms.2022.92862.2415
Maryam Babaei; Zahra Kanannejad; Najmeh Sepahi; Soheila Alyasin. "The Effect of COVID-19 Pandemic on Patients with Primary Immunodeficiency: A Cohort Study". سامانه مدیریت نشریات علمی, 47, 2, 1400, 162-166. doi: 10.30476/ijms.2022.92862.2415
Babaei, Maryam, Kanannejad, Zahra, Sepahi, Najmeh, Alyasin, Soheila. (1400). 'The Effect of COVID-19 Pandemic on Patients with Primary Immunodeficiency: A Cohort Study', سامانه مدیریت نشریات علمی, 47(2), pp. 162-166. doi: 10.30476/ijms.2022.92862.2415
Babaei, Maryam, Kanannejad, Zahra, Sepahi, Najmeh, Alyasin, Soheila. The Effect of COVID-19 Pandemic on Patients with Primary Immunodeficiency: A Cohort Study. سامانه مدیریت نشریات علمی, 1400; 47(2): 162-166. doi: 10.30476/ijms.2022.92862.2415

The Effect of COVID-19 Pandemic on Patients with Primary Immunodeficiency: A Cohort Study

Iranian Journal of Medical Sciences
مقاله 12، دوره 47، شماره 2، خرداد 2022، صفحه 162-166    اصل مقاله (196.03 K)
نوع مقاله: Brief Report(s)
شناسه دیجیتال (DOI): 10.30476/ijms.2022.92862.2415
نویسندگان
Maryam Babaei؛ Zahra Kanannejad؛ Najmeh Sepahi؛ Soheila Alyasin*
Allergy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
چکیده
Both adaptive and innate immune responses are essential for an effective defense against the severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) infection. We aimed to investigate the effect of the coronavirus disease 2019 (COVID-19) pandemic on patients with primary immunodeficiency (PID). This study was performed on patients who were diagnosed with PID by immunologist specialists and referred to Imam Reza Clinic of Asthma and Allergy, affiliated with Shiraz University of Medical Sciences, (Shiraz, Iran) for regular check-ups. The patients were enrolled in this cohort study and followed for any sign of COVID-19 from March 2020 to May 2021. COVID-19 infection was confirmed using a real-time polymerase chain reaction (RT-PCR) assay of nasal and pharyngeal swabs. Among the 90 PID patients under study, nine patients (10%) were diagnosed positive for COVID-19 infection. Five out of these nine patients belonged to the combined immunodeficiency (CID) category, while four patients were categorized as having primary antibody deficiencies (PADs). Eight patients with COVID-19 were required to be admitted to the hospital, and three patients died after hospitalization due to COVID-19 infection. It seems that patients with CID are at a higher risk of mortality, due to COVID-19 infection, that other types of PID.
کلیدواژه‌ها
COVID-19؛ Mortality؛ Primary immunodeficiency diseases
سایر فایل های مرتبط با مقاله
مراجع
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