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Hegazy, Mohamed, Shehadeh, Maamoun. (1401). Craniospinal Irradiation of Pediatric Medulloblastoma, Dosimetric Comparison between Helical Tomotherapy, and Conventional Radiation Therapy. سامانه مدیریت نشریات علمی, 13(4), 701-707. doi: 10.30476/mejc.2022.88933.1502
Mohamed W. Hegazy; Maamoun Shehadeh. "Craniospinal Irradiation of Pediatric Medulloblastoma, Dosimetric Comparison between Helical Tomotherapy, and Conventional Radiation Therapy". سامانه مدیریت نشریات علمی, 13, 4, 1401, 701-707. doi: 10.30476/mejc.2022.88933.1502
Hegazy, Mohamed, Shehadeh, Maamoun. (1401). 'Craniospinal Irradiation of Pediatric Medulloblastoma, Dosimetric Comparison between Helical Tomotherapy, and Conventional Radiation Therapy', سامانه مدیریت نشریات علمی, 13(4), pp. 701-707. doi: 10.30476/mejc.2022.88933.1502
Hegazy, Mohamed, Shehadeh, Maamoun. Craniospinal Irradiation of Pediatric Medulloblastoma, Dosimetric Comparison between Helical Tomotherapy, and Conventional Radiation Therapy. سامانه مدیریت نشریات علمی, 1401; 13(4): 701-707. doi: 10.30476/mejc.2022.88933.1502

Craniospinal Irradiation of Pediatric Medulloblastoma, Dosimetric Comparison between Helical Tomotherapy, and Conventional Radiation Therapy

Middle East Journal of Cancer
مقاله 15، دوره 13، شماره 4 - شماره پیاپی 52، دی 2022، صفحه 701-707    اصل مقاله (127.08 K)
نوع مقاله: Original Article(s)
شناسه دیجیتال (DOI): 10.30476/mejc.2022.88933.1502
نویسندگان
Mohamed W. Hegazy* 1، 2؛ Maamoun Shehadeh3
1Section of Radiation Oncology, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia
2Department of Clinical Oncology and Nuclear Medicine, Zagazig Medicine College, Egypt
3Department of Biomedical Physics, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia
چکیده
Background: Dosimetric comparison between 3D-conformal radiation therapy (3D-CRT) and helical tomotherapy (HT) in pediatric Medulloblastoma (MB) receiving craniospinal irradiation (CSI).
Method: This was a retrospective dosimetric study on five pediatric male patients diagnosed as MB, who were planned to receive CSI post-surgery. Treatment plans for 3D-CRT and HT were generated. Comparison was made in terms of planning target volume (PTV) coverage, homogeneity index (HI), conformity index (CI), organs at risk (OAR) dose, and treatment time (TT).
Results: HT increased the minimum dose up to PTV (81% vs. 74%) with better CI and HI (1.024 vs. 0.36 and 1.078 vs. 1.21, respectively). HT decreased the mean and maximum dose to OAR, except for higher mean dose of larynx, oral cavity, pharynx, and comparable V5 of lungs. TT of 3D CRT was shorter than HT (76 seconds vs. 545 seconds).
Conclusion: HT was found to be a better treatment option in all the MB cases receiving CSI regarding PTV, conformity, homogeneity, and most of OAR, while TT was shorter in 3D-CRT plan.
کلیدواژه‌ها
Pediatric؛ Medulloblastoma؛ Craniospinal irradiation؛ Dosimetry
اصل مقاله

How to cite this article:

Hegazy MW, Shehadeh M. Craniospinal irradiation of pediatric medulloblastoma, dosimetric comparison between helical tomotherapy, and conventional radiation therapy. Middle East J Cancer. 2022;13(4):701-7. doi: 10.3 0476/mejc.2022.88933.1502.

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