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Rahimian, Neda, Alibeik, Nazanin, Pishgar, Elham, Dini, Parisa, Abolmaali, Meysam, Mirzaasgari, Zahra. (1401). Manifestation of Ocular Myasthenia Gravis as an Initial Symptom of Coronavirus Disease 2019: A Case Report. سامانه مدیریت نشریات علمی, 47(4), 385-388. doi: 10.30476/ijms.2021.89841.2061
Neda Rahimian; Nazanin Alibeik; Elham Pishgar; Parisa Dini; Meysam Abolmaali; Zahra Mirzaasgari. "Manifestation of Ocular Myasthenia Gravis as an Initial Symptom of Coronavirus Disease 2019: A Case Report". سامانه مدیریت نشریات علمی, 47, 4, 1401, 385-388. doi: 10.30476/ijms.2021.89841.2061
Rahimian, Neda, Alibeik, Nazanin, Pishgar, Elham, Dini, Parisa, Abolmaali, Meysam, Mirzaasgari, Zahra. (1401). 'Manifestation of Ocular Myasthenia Gravis as an Initial Symptom of Coronavirus Disease 2019: A Case Report', سامانه مدیریت نشریات علمی, 47(4), pp. 385-388. doi: 10.30476/ijms.2021.89841.2061
Rahimian, Neda, Alibeik, Nazanin, Pishgar, Elham, Dini, Parisa, Abolmaali, Meysam, Mirzaasgari, Zahra. Manifestation of Ocular Myasthenia Gravis as an Initial Symptom of Coronavirus Disease 2019: A Case Report. سامانه مدیریت نشریات علمی, 1401; 47(4): 385-388. doi: 10.30476/ijms.2021.89841.2061

Manifestation of Ocular Myasthenia Gravis as an Initial Symptom of Coronavirus Disease 2019: A Case Report

Iranian Journal of Medical Sciences
مقاله 12، دوره 47، شماره 4، مهر 2022، صفحه 385-388    اصل مقاله (516.83 K)
نوع مقاله: Case Report(s)
شناسه دیجیتال (DOI): 10.30476/ijms.2021.89841.2061
نویسندگان
Neda Rahimian1؛ Nazanin Alibeik2؛ Elham Pishgar3؛ Parisa Dini2؛ Meysam Abolmaali4؛ Zahra Mirzaasgari* 4، 5
1Endocrine Research Center, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences, Tehran, Iran
2Firoozgar Clinical Research Development Center, Iran University of Medical Sciences, Tehran, Iran
3Gastrointestinal and Liver Diseases Research Center, Iran University of Medical Sciences, Tehran, Iran
4Shefa Neuroscience Research Center, Khatam Alanbia Hospital, Tehran, Iran
5Department of Neurology, Firoozgar Hospital, School of Medicine, Iran University of Medical Science, Tehran, Iran
چکیده
For a while, coronavirus disease-2019 (COVID-19) has been a major global pandemic. It primarily affects the respiratory system but has extrapulmonary manifestations such as gastrointestinal and neurological symptoms. Data on myasthenia gravis (MG), as a complication of COVID-19, are limited. We herein report the manifestation of ocular MG as an initial symptom of COVID-19. 
In November 2020, a 31-year-old healthy woman was referred to Firoozgar Hospital (Tehran, Iran) with left upper eyelid ptosis and diplopia as well as general weakness, myalgia, fever, and nasal congestion for four days prior to admission. Although the acetylcholine receptor antibody in her serum was negative, increased jitter in several muscles led to the diagnosis of ocular MG. Nasal swab reverse transcription-polymerase chain reaction (RT-PCR) assay tested positive for severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection. Computed tomography (CT) scan of the chest revealed bilateral ground-glass opacities and some foci of consolidation formation, but the thymus was normal. The patient was successfully treated with remdesivir and dexamethasone. The patient was eventually discharged in good condition and with improved neurological symptoms. 
A limited number of studies have suggested a possible association between MG and COVID-19. Therefore, further data are required to substantiate the proposed association. Clinicians should be aware of ocular MG during the COVID-19 pandemic to better diagnose and manage patients with SARS-CoV-2 infection.
کلیدواژه‌ها
COVID-19؛ Myasthenia gravis؛ SARS-CoV-2؛ Case report
سایر فایل های مرتبط با مقاله
مراجع
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