LinkedIn

 آمار

تعداد نشریات20
تعداد شماره‌ها1,113
تعداد مقالات10,208
تعداد مشاهده مقاله40,780,201
تعداد دریافت فایل اصل مقاله8,803,967
Savanović, Milovan, Štrbac, Bojan, Jaroš, Dražan, Loi, Mauro, Huguet, Florence, Foulquier, Jean-Noël. (1401). Quantification of Lung Tumor Motion and Optimization of Treatment. سامانه مدیریت نشریات علمی, 13(1), 65-76. doi: 10.31661/jbpe.v0i0.2102-1278
Milovan Savanović; Bojan Štrbac; Dražan Jaroš; Mauro Loi; Florence Huguet; Jean-Noël Foulquier. "Quantification of Lung Tumor Motion and Optimization of Treatment". سامانه مدیریت نشریات علمی, 13, 1, 1401, 65-76. doi: 10.31661/jbpe.v0i0.2102-1278
Savanović, Milovan, Štrbac, Bojan, Jaroš, Dražan, Loi, Mauro, Huguet, Florence, Foulquier, Jean-Noël. (1401). 'Quantification of Lung Tumor Motion and Optimization of Treatment', سامانه مدیریت نشریات علمی, 13(1), pp. 65-76. doi: 10.31661/jbpe.v0i0.2102-1278
Savanović, Milovan, Štrbac, Bojan, Jaroš, Dražan, Loi, Mauro, Huguet, Florence, Foulquier, Jean-Noël. Quantification of Lung Tumor Motion and Optimization of Treatment. سامانه مدیریت نشریات علمی, 1401; 13(1): 65-76. doi: 10.31661/jbpe.v0i0.2102-1278

Quantification of Lung Tumor Motion and Optimization of Treatment

Journal of Biomedical Physics and Engineering
مقاله 8، دوره 13، شماره 1، فروردین و اردیبهشت 2023، صفحه 65-76    اصل مقاله (1.57 M)
نوع مقاله: Original Research
شناسه دیجیتال (DOI): 10.31661/jbpe.v0i0.2102-1278
نویسندگان
Milovan Savanović* 1، 2؛ Bojan Štrbac3؛ Dražan Jaroš4، 5؛ Mauro Loi2؛ Florence Huguet2؛ Jean-Noël Foulquier2
1Faculty of Medicine, University of Paris-Saclay, 94276 Le Kremlin-Bicêtre, France
2Department of Radiation Oncology, Tenon Hospital, APHP, Sorbonne University, 75020 Paris, France
3MATER Private Hospital, Department of Physics, Eccles Street, Dublin 7, Ireland
4Center for Radiotherapy, International Medical Centers, Affidea, 78000 Banja Luka, Bosnia, and Herzegovina
5Faculty of Medicine, University of Banja Luka, 78000 Banja Luka, Bosnia, and Herzegovina
چکیده
Background: Mobility of lung tumors is induced by respiration and causes inadequate dose coverage. 
Objective: This study quantified lung tumor motion, velocity, and stability for small (≤5 cm) and large (>5 cm) tumors to adapt radiation therapy techniques for lung cancer patients.
Material and Methods: In this retrospective study, 70 patients with lung cancer were included that 50 and 20 patients had a small and large gross tumor volume (GTV). To quantify the tumor motion and velocity in the upper lobe (UL) and lower lobe (LL) for the central region (CR) and a peripheral region (PR), the GTV was contoured in all ten respiratory phases, using 4D-CT. 
Results: The amplitude of tumor motion was greater in the LL, with motion in the superior-inferior (SI) direction compared to the UL, with an elliptical motion for small and large tumors. Tumor motion was greater in the CR, rather than in the PR, by 63% and 49% in the UL compared to 50% and 38% in the LL, for the left and right lung. The maximum tumor velocity for a small GTV was 44.1 mm/s in the LL (CR), decreased to 4 mm/s for both ULs (PR), and a large GTV ranged from 0.4 to 9.4 mm/s.  
Conclusion: The tumor motion and velocity depend on the tumor localization and the greater motion was in the CR for both lobes due to heart contribution. The tumor velocity and stability can help select the best technique for motion management during radiation therapy.
کلیدواژه‌ها
Lung Cancer؛ Tumor Motion؛ Tumor Velocity؛ Tumor Stability؛ Four-Dimensional Computed Tomography؛ Stereotactic Body Radiotherapy؛ Radiotherapy؛ Intensity-Modulated Radiotherapy
سایر فایل های مرتبط با مقاله
مراجع
  1. Didkowska J, Wojciechowska U, Mańczuk M, Łobaszewski J. Lung cancer epidemiology: contemporary and future challenges worldwide. Ann Transl Med. 2016;4(8):150. doi: 10.21037/atm.2016.03.11. PubMed PMID: 27195268. PubMed PMCID: PMC4860480.
  2. Lemjabbar-Alaoui H, Hassan OU, Yang YW, Buchanan P. Lung cancer: Biology and treatment options. Biochim Biophys Acta. 2015;1856(2):189-210. doi: 10.1016/j.bbcan.2015.08.002. PubMed PMID: 26297204. PubMed PMCID: PMC4663145.
  3. Travis WD, Brambilla E, Riely GJ. New pathologic classification of lung cancer: relevance for clinical practice and clinical trials. J Clin Oncol. 2013;31(8):992-1001. doi: 10.1200/JCO.2012.46.9270. PubMed PMID: 23401443.
  4. Fernandez C, Grills IS, Ye H, Hope AJ, et al. Stereotactic Image Guided Lung Radiation Therapy for Clinical Early Stage Non-Small Cell Lung Cancer: A Long-Term Report From a Multi-Institutional Database of Patients Treated With or Without a Pathologic Diagnosis. Pract Radiat Oncol. 2020;10(4):e227-37. doi: 10.1016/j.prro.2019.12.003. PubMed PMID: 31837478.
  5. Keall PJ, Mageras GS, Balter JM, et al. The management of respiratory motion in radiation oncology report of AAPM Task Group 76. Med Phys. 2006;33(10):3874-900. doi: 10.1118/1.2349696. PubMed PMID: 17089851.
  6. Liauw SL, Connell PP, Weichselbaum RR. New paradigms and future challenges in radiation oncology: an update of biological targets and technology. Sci Transl Med. 2013;5(173):173sr2. doi: 10.1126/scitranslmed.3005148. PubMed PMID: 23427246. PubMed PMCID: PMC3769139.
  7. Chi A, Nguyen NP, Welsh JS, Tse W, et al. Strategies of dose escalation in the treatment of locally advanced non-small cell lung cancer: image guidance and beyond. Front Oncol. 2014;4:156. doi: 10.3389/fonc.2014.00156. PubMed PMID: 24999451. PubMed PMCID: PMC4064255.
  8. Fukui M, Takamochi K, Matsunaga T, et al. Risk of the preoperative underestimation of tumour size of lung cancer in patients with idiopathic interstitial pneumonias. Eur J Cardiothorac Surg. 2016;50(3):428-32. doi: 10.1093/ejcts/ezw065. PubMed PMID: 26987880.
  9. Lampen-Sachar K, Zhao B, Zheng J, et al. Correlation between tumor measurement on Computed Tomography and resected specimen size in lung adenocarcinomas. Lung Cancer. 2012;75(3):332-5. doi: 10.1016/j.lungcan.2011.08.001. PubMed PMID: 21890229. PubMed PMCID: PMC4441034.
  10. Bai T, Zhu J, Yin Y, Lu J, Shu H, Wang L, Yang B. How does four-dimensional computed tomography spare normal tissues in non-small cell lung cancer radiotherapy by defining internal target volume? Thorac Cancer. 2014;5(6):537-42. doi: 10.1111/1759-7714.12126. PubMed PMID: 26767049. PubMed PMCID: PMC4704343.
  11. Aznar MC, Persson GF, Kofoed IM, Nygaard DE, Korreman SS. Irregular breathing during 4DCT scanning of lung cancer patients: is the midventilation approach robust? Phys Med. 2014;30(1):69-75. doi: 10.1016/j.ejmp.2013.03.003. PubMed PMID: 23590980.
  12. Qian J, Xing L, Liu W, Luxton G. Dose verification for respiratory-gated volumetric modulated arc therapy. Phys Med Biol. 2011;56(15):4827-38. doi: 10.1088/0031-9155/56/15/013. PubMed PMID: 21753232. PubMed PMCID: PMC3360016.
  13. Giraud P, Morvan E, Claude L, Mornex F, Le Pechoux C, et al. Respiratory gating techniques for optimization of lung cancer radiotherapy. J Thorac Oncol. 2011;6(12):2058-68. doi: 10.1097/JTO.0b013e3182307ec2. PubMed PMID: 22052228.
  14. Prunaretty J, Boisselier P, Aillères N, Riou O, Simeon S, Bedos L, Azria D, Fenoglietto P. Tracking, gating, free-breathing, which technique to use for lung stereotactic treatments? A dosimetric comparison. Rep Pract Oncol Radiother. 2019;24(1):97-104. doi: 10.1016/j.rpor.2018.11.003. PubMed PMID: 30532657. PubMed PMCID: PMC6261085.
  15. Cozzi L, Fogliata A, Thompson S, Franzese C, et al. Critical Appraisal of the Treatment Planning Performance of Volumetric Modulated Arc Therapy by Means of a Dual Layer Stacked Multileaf Collimator for Head and Neck, Breast, and Prostate. Technol Cancer Res Treat. 2018;17:1-11. doi: 10.1177/1533033818803882. PubMed PMID: 30295172. PubMed PMCID: PMC6176542.
  16. Korreman SS. Image-guided radiotherapy and motion management in lung cancer. Br J Radiol. 2015;88(1051):20150100. doi: 10.1259/bjr.20150100. PubMed PMID: 25955231. PubMed PMCID: PMC4628536.
  17. Sarudis S, Karlsson Hauer A, Nyman J, Bäck A. Systematic evaluation of lung tumor motion using four-dimensional computed tomography. Acta Oncol. 2017;56(4):525-30. doi: 10.1080/0284186X.2016.1274049. PubMed PMID: 28075183.
  18. Liu HH, Balter P, Tutt T, et al. Assessing respiration-induced tumor motion and internal target volume using four-dimensional computed tomography for radiotherapy of lung cancer. Int J Radiat Oncol Biol Phys. 2007;68(2):531-40. doi: 10.1016/j.ijrobp.2006.12.066. PubMed PMID: 17398035.
  19. Hubie C, Shaw M, Bydder S, et al. A randomised comparison of three different immobilisation devices for thoracic and abdominal cancers. J Med Radiat Sci. 2017;64(2):90-6. doi: 10.1002/jmrs.202. PubMed PMID: 27998039. PubMed PMCID: PMC5454323.
  20. Shine NS, Paramu R, Gopinath M, Jaon Bos RC, Jayadevan PM. Out-of-Field Dose Calculation by a Commercial Treatment Planning System and Comparison by Monte Carlo Simulation for Varian TrueBeam®. J Med Phys. 2019;44(3):156-75. doi: 10.4103/jmp.JMP_82_18. PubMed PMID: 31576064. PubMed PMCID: PMC6764172.
  21. Van Sörnsen De Koste JR, Lagerwaard FJ, Nijssen-Visser MR, et al. Tumor location cannot predict the mobility of lung tumors: a 3D analysis of data generated from multiple CT scans. Int J Radiat Oncol Biol Phys. 2003;56(2):348-54. doi: 10.1016/s0360-3016(02)04467-x. PubMed PMID: 12738308.
  22. Miura H, Masai N, Oh RJ, Shiomi H, Sasaki J, Inoue T. Approach to dose definition to the gross tumor volume for lung cancer with respiratory tumor motion. J Radiat Res. 2013;54(1):140-5. doi: 10.1093/jrr/rrs054. PubMed PMID: 22951318. PubMed PMCID: PMC3534263.
  23. Seppenwoolde Y, Shirato H, Kitamura K, et al. Precise and real-time measurement of 3D tumor motion in lung due to breathing and heartbeat, measured during radiotherapy. Int J Radiat Oncol Biol Phys. 2002;53(4):822-34. doi: 10.1016/s0360-3016(02)02803-1. PubMed PMID: 12095547.
  24. Shirato H, Suzuki K, Sharp GC et al. Speed and amplitude of lung tumor motion precisely detected in four-dimensional setup and in real-time tumor-tracking radiotherapy. Int J Radiat Oncol Biol Phys. 2006;64(4):1229-36. doi: 10.1016/j.ijrobp.2005.11.016. PubMed PMID: 16504762.
  25. Lee SY, Lim S, Ma SY, Yu J. Gross tumor volume dependency on phase sorting methods of four-dimensional computed tomography images for lung cancer. Radiat Oncol J. 2017;35(3):274-80. doi: 10.3857/roj.2017.00444. PubMed PMID: 29037025. PubMed PMCID: PMC5647759.
  26. Underberg RW, Lagerwaard FJ, Slotman BJ, et al. Benefit of respiration-gated stereotactic radiotherapy for stage I lung cancer: an analysis of 4DCT datasets. Int J Radiat Oncol Biol Phys. 2005;62(2):554-60. doi: 10.1016/j.ijrobp.2005.01.032. PubMed PMID: 15890600.
آمار
تعداد مشاهده مقاله: 1,010
تعداد دریافت فایل اصل مقاله: 287


سامانه مدیریت نشریات علمی. قدرت گرفته از سیناوب