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Omidvari, Shapour, Eskandari, Zahra, Nasrollahi, Hamid, Ahmadloo, Niloofar, Ansari, Mansour, Hamedi, Seyed Hassan, Khanjani, Nezhat, Kadkhodaei, Behnam, Mosalaei, Ahmad, Mohammadianpanah, Mohammad. (1401). The Investigation of Prophylactic Effect of StrataXRT Gel on Radiation-Induced Dermatitis in Breast Cancer Patients: A Randomized Clinical Trial. سامانه مدیریت نشریات علمی, 13(2), 293-298. doi: 10.30476/mejc.2021.86775.1372
Shapour Omidvari; Zahra Eskandari; Hamid Nasrollahi; Niloofar Ahmadloo; Mansour Ansari; Seyed Hassan Hamedi; Nezhat Khanjani; Behnam Kadkhodaei; Ahmad Mosalaei; Mohammad Mohammadianpanah. "The Investigation of Prophylactic Effect of StrataXRT Gel on Radiation-Induced Dermatitis in Breast Cancer Patients: A Randomized Clinical Trial". سامانه مدیریت نشریات علمی, 13, 2, 1401, 293-298. doi: 10.30476/mejc.2021.86775.1372
Omidvari, Shapour, Eskandari, Zahra, Nasrollahi, Hamid, Ahmadloo, Niloofar, Ansari, Mansour, Hamedi, Seyed Hassan, Khanjani, Nezhat, Kadkhodaei, Behnam, Mosalaei, Ahmad, Mohammadianpanah, Mohammad. (1401). 'The Investigation of Prophylactic Effect of StrataXRT Gel on Radiation-Induced Dermatitis in Breast Cancer Patients: A Randomized Clinical Trial', سامانه مدیریت نشریات علمی, 13(2), pp. 293-298. doi: 10.30476/mejc.2021.86775.1372
Omidvari, Shapour, Eskandari, Zahra, Nasrollahi, Hamid, Ahmadloo, Niloofar, Ansari, Mansour, Hamedi, Seyed Hassan, Khanjani, Nezhat, Kadkhodaei, Behnam, Mosalaei, Ahmad, Mohammadianpanah, Mohammad. The Investigation of Prophylactic Effect of StrataXRT Gel on Radiation-Induced Dermatitis in Breast Cancer Patients: A Randomized Clinical Trial. سامانه مدیریت نشریات علمی, 1401; 13(2): 293-298. doi: 10.30476/mejc.2021.86775.1372

The Investigation of Prophylactic Effect of StrataXRT Gel on Radiation-Induced Dermatitis in Breast Cancer Patients: A Randomized Clinical Trial

Middle East Journal of Cancer
مقاله 10، دوره 13، شماره 2 - شماره پیاپی 50، تیر 2022، صفحه 293-298    اصل مقاله (109.55 K)
نوع مقاله: Original Article(s)
شناسه دیجیتال (DOI): 10.30476/mejc.2021.86775.1372
نویسندگان
Shapour Omidvari1؛ Zahra Eskandari2؛ Hamid Nasrollahi* 2؛ Niloofar Ahmadloo1؛ Mansour Ansari1؛ Seyed Hassan Hamedi2؛ Nezhat Khanjani2؛ Behnam Kadkhodaei2؛ Ahmad Mosalaei2؛ Mohammad Mohammadianpanah3
1Breast Diseases Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
2Radiation Oncology Department, Shiraz University of Medical Sciences, Shiraz, Iran
3Colorectal Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
چکیده
Background: Breast cancer is among the most prevalent cancers in women. Radiotherapy is an important part in treatment of breast cancer, associated with some side-effects, including skin dermatitis. Dermatitis may be severe and impair quality of life. Multiple agents have been studied, but no standard treatment is yet available. Silicone based gel (StrataXRT) was promising in some studies in reducing skin inflammation and also radiotherapy-induced dermatitis.
Method: This was a randomized trial on 100 women with breast cancer who had undergone quadrantectomy for breast cancer. They received StrataXRT gel or best supportive care during radiotherapy. Dermatitis area and grade of dermatitis were measured.
Results: Regarding the mean size of radiation-induced dermatitis area, there was a significant difference between the intervention (36.88 cm2 ± 69.93) and control (83.83 cm2 ± 79.34) groups (P = 0.002). During radiotherapy, except in the fourth week, dermatitis was significantly more severe in the control group.
Conclusion: It seems that StrataXRT is helpful in decreasing radiotherapy-induced dermatitis.
کلیدواژه‌ها
Breast neoplasms؛ Radiotherapy؛ Dermatitis
اصل مقاله

How to cite this article:

Omidvari S, Eskandari Z, Nasrollahi H, Ahmadloo N, Ansari M, Hamedi SH, et al. The investigation of prophylactic effect of StrataXRT gel on radiation-induced dermatitis in breast cancer patients: a randomized clinical trial. Middle East J Cancer. 2022;13(2):293-8. doi: 10.30 476/mejc.2021.86775.1372.

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