پیوندهای مفید
آمار
| تعداد نشریات | 20 |
| تعداد شماره‌ها | 1,113 |
| تعداد مقالات | 10,208 |
| تعداد مشاهده مقاله | 40,779,934 |
| تعداد دریافت فایل اصل مقاله | 8,803,872 |
Effectiveness of Nanoparticle-Based Acidulated Phosphate Fluoride (APF) Gel on Surface Enamel Fluoride Uptake: an Interventional Study | ||
| Journal of Dentistry | ||
| مقاله 7، دوره 23، شماره 1 - شماره پیاپی 74، خرداد 2022، صفحه 40-50 اصل مقاله (931.25 K) | ||
| نوع مقاله: Original Article | ||
| شناسه دیجیتال (DOI): 10.30476/dentjods.2021.87895.1295 | ||
| نویسندگان | ||
| Anusha Raghavan* 1؛ Aparna Sukumaran1؛ Madan Kumar Parangimalai Diwakar2 | ||
| 1Dept. of Public Health Dentistry, 2/102,East coast road, Uthandi, Chennai-600119, Tamil Nadu, India. | ||
| 2Dept. of Public Health Dentistry, Ragas Dental College and Hospital, Tamil Nadu, India. | ||
| چکیده | ||
| Statement of the Problem:Despite topical fluoride being used for over 50 years in caries prevention, its complete potential in terms of formation of fluorapatite enamel and prolonged surface retention has not been harnessed. Purpose: This study aimed to assess the effectiveness of nanoparticle based acidulated phosphate fluoride (APF) gel on surface enamel fluoride uptake through split mouth design over a period of six months, on patients undergoing orthodontic treatment and indicated for bilateral extraction of premolars on at least one of the arch. Materials and Method: A split mouth non randomized clinical trial was performed.Each of the 30 participants received one application of 4 minutes duration of both the intervention: Right half of the mouth received nanoparticle based APF gel, and left half of the mouth received conventional APF gel (16 Oz Pascal Corp.; strawberry flavor). Bilateral acid etch biopsy of enamel surface was take at 3 intervals- baseline,24 hours and 30 days. Using 1ml of 0.5M perchloric acid, acid etch enamel biopsy was taken for all the study subjects at 3 intervals of time (baseline, 24 hours and 30 days), bilaterally on the buccal and palatal/lingual surface of maxillary or mandibular premolars indicated for extraction, using 1 (l of 0.5M perchloric acid. After the premolars were extracted, scanning electron microscope (SEM) analysis was done to determine the surface characteristics of enamel in both groups. Results:Overall, both fluoride uptake and depth of biopsy remained significant even after controlling for the covariates (time, group) individually and simultaneously (p < 0.05). Further analysis showed that fluoride uptake was significantly increased and biopsy depth significantly decreased in the nanoparticle based APF gel group at 24 hour and 30 day evaluation respectively. Conclusion: By reducing the size of sodium fluoride to increase the surface enamel uptake, our results support the use of this top down approach as a promising strategy for effective delivery of topical fluorides.This highlights that the top down approach of nanoscience to reduce the size active compound sodium fluoride has increased the uptake and retention of surface enamel fluoride. | ||
| کلیدواژه‌ها | ||
| APF gel؛ Biopsy؛ Enamel fluoride؛ Nanoparticles | ||
|
سایر فایل های مرتبط با مقاله
|
||
| مراجع | ||
|
[1] Fejerskov O. Fluorides in dentistry. 2nd ed. Denmark: Munksgaard Textbooks; 1996. p. 99-100.
[2] Murray JJ. Fluorides in caries prevention. 3rd ed. London: Wright PSG; 1991. p. 99-113.
[3] American Dental Association Council on Scientific Affairs. Professionally applied topical fluoride: Evidence-based clinical recommendations. J Am Dent Assoc. 2006; 137: 1151-1159.
[4] Wei SH, Chik FF. Fluoride retention following topical fluoride foam and gel application. Pediatr Dent. 1990; 12: 368-374.
[5] Drexler KE. Engines of Creation: The Coming Era of Nanotechnology. 1th ed. New York: Anchor Press; 1986. p. 99-129.
[6] Abou Neel EA, Bozec L, Perez RA, Kim HW, Knowles JC. Nanotechnology in dentistry: prevention, diagnosis and therapy. Int J Nanomedicine. 2015; 10: 6371-6394.
[7] Weatherell, JA, Robinson C, Hallsworth AS. Changes in the fluoride concentration of the labial surface with age. Caries Res. 1972; 6: 312.
[8] Hellstrom I, Ericsson Y. Fluoride reactions with dental enamel following different forms of fluoride supply.Scand J Dent Res. 1976: 84: 255-267.
[9] Delbem AC, Cury JA. Effect of application time of APF and NaF gels on microhardness and fluoride uptake of in vitro enamel caries. Am J Dent. 2002; 15: 169-172.
[10] Jabbarifar SE, Salavati S, Akhavan A, Khosravi K, Tavakoli N, Nilchian F. Effect of fluoridated dentifrices on surface microhardness of the enamel of deciduous teeth. Dent Res J (Isfahan) 2011; 9: 113–117.
[11] Anusha R, Arthi B, Iyer K, Balashanmugam. P, Madan kumar PD. Effectiveness of nanoparticle based acidulated phosphate fluoride (APF) gel and conventional APF gel on surface microhardness characteristic of human enamel: an in vitro study. Fluoride 2018; 52 (3 Pt 1): 221-230.
[12] Brudevold F, Savoury A, Gardner DEl. A study of acidulated fluoride solutions I- in vitro effects on enamel. Arch
Oral Biol. 1963; 8: 167.
[13] Bruun C, Stoltze K. In vivo uptake of fluoride by surface enamel of cleaned and plaque-covered teeth. Scand J Dent Res. 1976; 84: 268-275.
[14] Lenzi TL, Montagner AF, Soares FZ, de*Oliveira*Rocha R. Are topical fluorides effective for treating incipient carious lesions? A systematic review and metaanalysis. The J Am Dent Assoc. 2016; 147: 84-91.
[15] Weyant RJ, Tracy SL, Anselmo T. Topical fluoride for caries prevention: Executive summary of the updated clinical recommendations and supporting systematic review. J Am Dent Assoc. 2013; 144: 1279–1291.
[16] Whitford GM, Adair SM, Hanes CM, Perdue EC, Russell CM. Enamel uptake and patient exposure to fluoride: comparison of APF gel and foam. Pediatr Dent. 1995; 17: 199-203.
[17] Nishioka Y, Nakagaki H, Kato S, Morita I, Kurosu K. Fluoride profiles in different sites of approximal surfaces of second primary molars after topical application of acidulated phosphate fluoride gel in vivo. Archs Oral Biol. 1995; 40: 1157-1161.
[18] Calvo AFB, Tabchoury CPM, Del*Bel*Cury AA, Tenuta LMA, da*Silva WJ, Cury JA. Effect of acidulated phosphate fluoride gel application time on enamel demineralization of deciduous and permanent teeth. Caries Res. 2012; 46: 31–37.
[19] Houpt M, Koenigsberg S, Shey Z. The effect of prior tooth cleaning on the efficacy of topical fluoride treatment: two-year results. Clin Prev Dent. 1983; 5: 8-10.
[20] Katz RV, Meskin LH, Jensen ME, Keller D. Topical fluoride and prophylaxis: a 30-month clinical trial [Abstract]. J Dent Res. 1984; (Spec Iss) 63: 256.
[21] Ripa LW, Leske GS, Sposato A, Varma A. Effect of prior tooth cleaning on biannual professional APF topical fluoride gel-tray treatments: results after three years. Caries Res. 1984; 18: 457-464.
[22] Chand BR, Kulkarni S, Mishra P. Inhibition of enamel demineralisation using "Nd-YAG and diode laser assisted fluoride therapy". Eur Arch Paediatr Dent. 2016; 17: 59-64.
[23] Zancopé BR, Rodrigues LP, Parisotto TM, Steiner-Oliveira C, Rodrigues LK, Nobredos Santos M. laser irradiation enhances CaF2 formation and inhibits lesion progression on demineralized dental enamel- in vitro study. Lasers Med Sci. 2016; 31: 539-547.
[24] Kim YM, Lee HY, Lee HJ, Kim JB, Kim S, Joo JY, et al. Retention improvement in fluoride application with cold Atmospheric Plasma. J Dent Res. 2018; 97: 179-183.
[25] Souza BM, Comar LP, Constantino MV, Neto F, Buzalaf MAR, Magalhaes AC. Effect of an experimental paste with hydroxyapatite nanoparticles and fluoride on dental demineralisation and remineralisation in situ. Caries Res. 2015; 49: 499–507.
[26] Dijkman AG, de*Boer P, Arends J. In vivo investigation on the fluoride content in and on Human enamel after topical application. Caries Res. 1983; 17: 392-402.
[27] Wei SHY, Connor Jr CW. Fluoride Uptake and Retention in vitro Following Topical Fluoride Applications. J Dent Res. 1983; 62: 830-832.
[28] Pai N, McIntyre J, Tadic N, Laparidis C. Comparative uptake of fluoride ion into enamel from various topical fluorides in vitro. Aus Dent J. 2007; 52: 41-46.
[29] Nelson DG, Jongebloed WL, Arends J. Morphology of enamel surfaces treated with topical fluoride agents: SEM considerations. J Dent Res. 1983; 62: 1201-128.
[30] Nelson DG, Jongebloed WL, Arends J. Crystallographic structure of enamel surfaces treated with topical fluoride agents: TEM and XRD considerations. J Dent Res. 1984; 63: 6-12.
[31] Oliveira M, Mansur HS. Synthetic Tooth Enamel: SEM characterization of a fluoride hydroxyapatite coating for dentistry applications. Materials Research. 2007; 10: 115-118.
[32] Brudevold F, McCann HG, Gron P. An enamel biopsy method for determination of fluoride in human teeth. Archs Oral Biol. 1968; 13: 877-885. | ||
|
آمار تعداد مشاهده مقاله: 1,775 تعداد دریافت فایل اصل مقاله: 1,543 |
||
