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Aghajani, Saeedeh, Jafari, Sanaz, Zarshenas, Mohammad M., Abolhassanzadeh, Zohreh. (1400). Volatile composition analysis and quantitative determination of specific markers in a traditional preparation, Jawārish-e-Komooni. سامانه مدیریت نشریات علمی, 7(4), 259-268. doi: 10.30476/tips.2021.91274.1098
Saeedeh Aghajani; Sanaz Jafari; Mohammad M. Zarshenas; Zohreh Abolhassanzadeh. "Volatile composition analysis and quantitative determination of specific markers in a traditional preparation, Jawārish-e-Komooni". سامانه مدیریت نشریات علمی, 7, 4, 1400, 259-268. doi: 10.30476/tips.2021.91274.1098
Aghajani, Saeedeh, Jafari, Sanaz, Zarshenas, Mohammad M., Abolhassanzadeh, Zohreh. (1400). 'Volatile composition analysis and quantitative determination of specific markers in a traditional preparation, Jawārish-e-Komooni', سامانه مدیریت نشریات علمی, 7(4), pp. 259-268. doi: 10.30476/tips.2021.91274.1098
Aghajani, Saeedeh, Jafari, Sanaz, Zarshenas, Mohammad M., Abolhassanzadeh, Zohreh. Volatile composition analysis and quantitative determination of specific markers in a traditional preparation, Jawārish-e-Komooni. سامانه مدیریت نشریات علمی, 1400; 7(4): 259-268. doi: 10.30476/tips.2021.91274.1098

Volatile composition analysis and quantitative determination of specific markers in a traditional preparation, Jawārish-e-Komooni

Trends in Pharmaceutical Sciences
مقاله 5، دوره 7، شماره 4، اسفند 2021، صفحه 259-268    اصل مقاله (1.4 M)
نوع مقاله: Original Article
شناسه دیجیتال (DOI): 10.30476/tips.2021.91274.1098
نویسندگان
Saeedeh Aghajani1؛ Sanaz Jafari2؛ Mohammad M. Zarshenas* 1، 2، 3؛ Zohreh Abolhassanzadeh4
1Medicinal Plants Processing Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
2Departmentvof Phytopharmaceuticals (Traditional Pharmacy), School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran
3Epilepsy Research Center, Shiraz University of Medical Sciences, Shiraz, IranEssence of Parsiyan Wisdom Institute, Traditional Medicine and Medicinal Plant Incubator, Shiraz University of Medica
4Medical Plants Research Center, Basic Health Sciences Institute,Shahrekord University of Medical Sciences, Shahrekord, Iran
چکیده
The control and standardization process of herbal products is a critical point in traditional medicine. Many drugs that are being used today are not standardized and also there is no noticeable control over them. Out of all the different pharmaceutical dosage forms mentioned in Traditional Persian Medicine literature, Jawarish-e-Komooni is an effective formulation due to its positive effect on Gastrointestinal disorders. This formulation includes Zingiber officinale, Bunium persicum, Piper nigrum, and also honey. At this time there have been no noticeable and proven control and standardization or any pharmacognosy studies on this formulation.
In this study, Jawarish-e-Komooni was prepared from Qarābadin-e-Salehi, one of the Traditional Persian Medicine literature. Then, by using gas chromatography/mass spectroscopy (GC/MS) and HPTLC, the containing of the formulation were assessed. Also for content determination, using Gas chromatography/ flame ionization detector (GC/FID), two of the main ingredients were determined. The HPTLC results showed piperine and gamma-terpinene as the main components of the formulation. In the standardizing process, piperine and gamma-terpinene were respectively proved to be 0.22% and 0.97% of the whole preparation. Also by calculating the standard deviation of the content determination process, we could reach the point where RSD was less than 10%, which is proof of the validity of our method. As mentioned before, standardization is a critical process for all the traditional preparations and it could help us gain repetitive drug responses elsewhere.
کلیدواژه‌ها
Jawarish-e-Komooni؛ standardization؛ HPTLC؛ GC/MS؛ GC/FID
مراجع
1. Kunle OF, Egharevba HO, Ahmadu PO. Standardization of herbal medicines-A review. Int J Biodiver. Conserv. 2012 Mar 20;4(3):101-12.
2. Hamedi A, Zarshenas MM, Sohrabpour M, Zargaran A. Herbal medicinal oils in traditional Persian medicine. Pharm Biol. 2013 Sep;51(9):1208-18. doi: 10.3109/13880209.2013.777462. Epub 2013 Jun 7. PMID: 23746335.
3. Mahmoudpour Z, Shirafkan H, Mojahedi M, Gorji N, Mozaffarpur SA. Digesters in traditional Persian medicine. Caspian J Intern Med. 2018 Winter;9(1):1-6. doi: 10.22088/cjim.9.1.1. PMID: 29387312; PMCID: PMC5771353.
4. Heravi MG. (1765). Qarabadin-e-Salehi. Tehran, Iran: Dar-ol-khalafeh(Litograph in Persian).
5. Iranian Herbal Pharmacopoeia Commission. Iranian Herbal Pharmacopoeia. Ministry of Health, Treatment and Medical Education, Tehran, 2003.
6. Chrubasik S, Pittler MH, Roufogalis BD. Zingiberis rhizoma: a comprehensive review on the ginger effect and efficacy profiles. Phytomedicine. 2005 Sep;12(9):684-701. doi: 10.1016/j.phymed.2004.07.009. PMID: 16194058.
7. Mao QQ, Xu XY, Cao SY, Gan RY, Corke H, Beta T, Li HB. Bioactive Compounds and Bioactivities of Ginger (Zingiber officinale Roscoe). Foods. 2019 May 30;8(6):185. doi: 10.3390/foods8060185. PMID: 31151279; PMCID: PMC6616534.
8. Sharififar F, Yassa N, Mozaffarian V. Bioactivity of major components from the seeds of Bunium persicum (Boiss.) Fedtch. Pak J Pharm Sci. 2010 Jul;23(3):300-4. PMID: 20566444.
9. Samani SM, Moein M, Petramfar P, Zarshenas MM. Development and Assessment of a Gas Chromatographic Based Method for the Quantification of Thymol from Cream Based Formulation. Curr Drug Discov Technol. 2016;13(2):77-83. doi: 10.2174/1570163813666160519111145. PMID: 27193568.
10. Ryding O. Pericarp structure and phylogeny of theLamiaceae-Verbenaceae-complex. Plant Syst Evol. 1995 Mar 1;198(1-2):101-41.
11. Högnadóttir A, Rouseff RL. Identification of aroma active compounds in orange essence oil using gas chromatography-olfactometry and gas chromatography-mass spectrometry. J Chromatogr A. 2003 May 23;998(1-2):201-11. doi: 10.1016/s0021-9673(03)00524-7. PMID: 12862384.
12. Adams RP. Identification of essential oil components by gas chromatography/mass spectrometry. Carol Stream. 1995;16:65-120..
13. Creed MC, Milgram NW. Amyloid-modifying therapies for Alzheimer's disease: therapeutic progress and its implications. Age (Dordr). 2010 Sep;32(3):365-84. doi: 10.1007/s11357-010-9142-z. Epub 2010 Apr 20. PMID: 20640545; PMCID: PMC2926857.
14. Binder RG, Flath RA, MonTR. Volatile components of bittermelon. J Agric Food Chem. 1989;37(2):418-20.
15. Tongnuanchan P, Benjakul S. Essential oils: extraction, bioactivities, and their uses for food preservation. J Food Sci. 2014 Jul;79(7):R1231-49. doi: 10.1111/1750-3841.12492. Epub 2014 Jun 2. PMID: 24888440.
16. Danin A, Ravid U, Umano K, Shibamoto T. Essential oil composition of Origanum ramonense Danin leaves from Israel. J Essent Oil Res. 1997;9(4):411-17.
17. Chen J, Ho CT. Volatile compounds generated in serine-monosaccharide model systems. J Agric Food Chem. 1998;46(4):1518-1522.
18. Mondello L, ZappiaG, Cotroneo A, Bonaccorsi I, Chowdhury JU, Yusuf M, et al. Studies on the essential oil-bearing plants of Bangladesh. Part VIII. Composition of some Ocimum oils O. basilicum L. var. purpurascens; O. sanctum L. green; O. sanctum L. purple; O. americanum L., citral type; O. americanum L., Camphor Type. Flavour Fragr J. 2002;17(5):335-340.
19. Flamini G, Luigi Cioni P, Morelli I, Celik S, Suleyman Gokturk R, Unal O. Essential oil of Stachys aleurites from Turkey. Biochem Syst Ecol. 2005;33(1):61-6.
20. Lee N-H, Lee S-M, Lee T-M, Chung N, Lee H-S. GC-MS Analyses of the Essential Oils Obtained from Pinaceae Leaves in Korea. J Essent Oil Bear Plant. 2015;18(3):538-42.
21. Abdullahi AA. Trends and challenges of traditional medicine in Africa. Afr J Tradit Complement Altern Med. 2011;8(5 Suppl):115-23. doi: 10.4314/ajtcam.v8i5S.5. Epub 2011 Jul 3. PMID: 22754064; PMCID: PMC3252714.
22. World Health Organisation. General Guidelines for Methodologies of Research and Evaluation of Traditional Medicine; World Health Organisation: Geneva, Switzerland, 2000.
23. Mikaili P, Shayegh J, Asghari MH, Sarahroodi S, Sharifi M. Currently used traditional phytomedicines with hot nature in Iran. Ann Biol Res. 2011;2(5):56-68.
24. Choudhary N, Sekhon BS. An overview of advances in the standardization of herbal drugs. J Pharm Educ Res. 2011 Dec 1;2(2):55.
25. Jafari S, Jalali A, Abolhassanzadeh Z,Farboodniay Jahromi MA, Zarshenas MM. Gas and high performance thin layer chromatographic based-determinationmethod forquantification of thymol in semisolidtraditional dosage forms. Biointerface Res Appl Chem. 2020;10 (2):4982-4987.

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