Effect of High-Intensity Interval Resistance Training on Appendicular Skeletal Muscle Mass Index Measured by Bioelectric Impedance Analysis in Sarcopenic Elderly Women

Hooshmandi, Zeinab; Daryanoosh, Farhad; Nemati, Javad; Jalli, Reza

doi:10.30476/whb.2021.90850.1120

تعداد نشریات	20
تعداد شماره‌ها	1,149
تعداد مقالات	10,518
تعداد مشاهده مقاله	45,415,564
تعداد دریافت فایل اصل مقاله	11,291,386

	Effect of High-Intensity Interval Resistance Training on Appendicular Skeletal Muscle Mass Index Measured by Bioelectric Impedance Analysis in Sarcopenic Elderly Women
Women’s Health Bulletin
مقاله 3، دوره 8، شماره 4 - شماره پیاپی 31، دی 2021، صفحه 211-219 اصل مقاله (365.31 K)
نوع مقاله: Research Article
شناسه دیجیتال (DOI): 10.30476/whb.2021.90850.1120
نویسندگان
Zeinab Hooshmandi¹^{، 2}؛ Farhad Daryanoosh¹؛ Javad Nemati¹؛ Reza Jalli^* ³
¹Department of Sport Sciences, Shiraz University, Shiraz, Iran
²Department of Exercise Physiology, Payam Noor University, Shiraz, Iran
³Medical Imaging Research Center; Shiraz University of Medical Sciences, Shiraz, Iran
چکیده
Background: Aging is an inevitable physiological process leading to a progressive decrease in muscle mass and function, which is called sarcopenia. Correspondingly, this study aimed to investigate the effect of High-Intensity Interval Resistance Training (HIIRT) on certain sarcopenia-related factors in elderly women. Methods: This was a quasi-experimental study in which thirty elderly women aged 60 to 70 years, from April to September 2020, volunteered to participate and were randomly assigned to the experimental (n=15) and control (n=15) groups. Body Mass Index (BMI), Appendicular Skeletal Muscle Mass (ASM), Appendicular Skeletal Muscle Mass Index (ASMI), and body fat percentage were measured using bioelectric impedance analysis; handgrip strength was measured via Jamar dynamometer; walking speed was measured employing six-meter walking test (6MWT); IGF-1 level (μg/L) was measured with Mediagnost kit (Germany) and serum myostatin level (ng/L) was measured using ELISA kit from R&D Company (USA) via Enzyme-Linked Immuno Sorbent Assay )ELISA( method in two stages: pre-test (week 0) and post-test (end of week 8). Independent t-test was subsequently utilized to assess the research variables through SPSS software version 23 at 0.05 level of significance. Results: The results indicated a significant decrease in body fat percentage (1.05±0.79, p <0.001) and Myostatin (MSTN) (87.25±82.38, p <0.01) and a significant increase in handgrip strength (-08.58±4.50, p <0.001), ASM (-4.91±0.28, p <0.001), ASMI (-0.19±0.11, p <0.001), and 6MWT (-0.42±0.26, p <0.001) in the experimental group compared to the control. There was also an increase in IGF-1 (-0.83±2.90, P=0.88), yet it was not significant. Conclusion: The major components indicative of sarcopenia were improved through High-Intensity Interval Resistance Training. Therefore, HIIRT appeared to be one of the most important coping strategies for reduction of muscle mass and strength in older women. We could thus conclude that it is necessary for the elderly to do this type of training.
کلیدواژه‌ها
Resistance training؛ Aging؛ strength؛ Sarcopenia؛ Insulin-like growth factor-1؛ Myostatin

مراجع
1. Bowen TS, Schuler G, Adams V. Skeletal muscle wasting in cachexia and sarcopenia: molecular pathophysiology and impact of exercise training. J Cachexia Sarcopenia Muscle. 2015;6(3):197-207. doi: 10.1002/jcsm.12043. PubMed PMID: 26401465; PubMed Central PMCID: PMC4575550. ## 2. Abbasi-Shavazi M, Anbari-Nogyni Z. A need to address different dimensions of aging challenges of Iranian elderly for publishing in elderly health journal. Elderly Health Journal. 2019;5(1):1-2. doi: 10.18502/ehj.v5i1.1184. ## 3. Yu J. The etiology and exercise implications of sarcopenia in the elderly. International Journal of Nursing Sciences. 2015;2(2):199-203. doi: 10.1016/j.ijnss.2015.04.010. ## 4. Bao W, Sun Y, Zhang T, Zou L, Wu X, Wang D, Chen Z. Exercise Programs for Muscle Mass, Muscle Strength and Physical Performance in Older Adults with Sarcopenia: A Systematic Review and Meta-Analysis. Aging Dis. 2020;11(4):863-873. doi: 10.14336/AD.2019.1012. PubMed PMID: 32765951; PubMed Central PMCID: PMC7390512. ## 5. Brown DM, Goljanek-Whysall K. microRNAs: Modulators of the underlying pathophysiology of sarcopenia? Ageing Res Rev. 2015;24(Pt B):263–73. doi: 10.1016/j.arr.2015.08.007. PubMed PMID: 26342566. ## 6. Galancho-Reina I, Sanchez-Oliver AJ, González Matarín PJ, Butragueno J, Bandera-Merchan B, Carmona WS, et al. The Role of Muscle Tissue and Resistance Training in Cardiometabolic Health. Int J Sports Sci Med. 2019;3(1):1-12. ## 7. Dimmeler S, Nicotera, P. MicroRNAs in age-related diseases. EMBO Mol Med. 2013;5(2):180–90. doi: 10.1002/emmm.201201986. PubMed PMID: 23339066; PubMed Central PMCID: PMC3569636. ## 8. McGregora RA, Poppitta SD, Cameron-Smith D. Role of microRNAs in the age-related changes in skeletal muscle and diet or exercise interventions to promote healthy aging in humans. Ageing Res Rev. 2014;17:25–33. doi: 10.1016/j.arr.2014.05.001. PubMed PMID: 24833328. ## 9. Bowen TS, Schuler G, Adams V. Skeletal muscle wasting in cachexia and sarcopenia: molecular pathophysiology and impact of exercise training. J Cachexia Sarcopenia Muscle. 2015;6(3):197–207. doi: 10.1002/jcsm.12043. PubMed PMID: 26401465; PubMed Central PMCID: PMC4575550. ## 10. Negaresh R, Ranjbar R, Baker JS, Habibi A, Mokhtarzade M, Momen Gharibvand M, Fokin A. Skeletal Muscle hypertrophy, IGF-1, Myostatin and Follistatin in Healthy and Sarcopenic Elderly Men: The Effect of whole-body Resistance Training. Int J Prev Med. 2019;10:29. doi: 10.4103/ijpvm.IJPVM_310_17. PubMed PMID: 30967915; PubMed Central PMCID: PMC6425763. ## 11. Schoenfeld B. Science and Development of Muscle Hypertrophy. New York: Lehman College, Bronx; 2015. ## 12. Forbes SC, Little JP, Candow DG. Exercise and nutritional interventions for improving aging muscle health. Endocrine. 2012;42(1):29–38. doi: 10.1007/s12020-012-9676-1. PubMed PMID: 22527891. ## 13. Shanazari Z, Faramarzi M, Banitalebi E, Hemmati R. Effect of moderate and high-intensity endurance and resistance training on serum concentrations of MSTN and IGF-1 in old male Wistar rats. Horm Mol Biol Clin Investig. 2019;38(2). doi: 10.1515/hmbci-2018-0066. PubMed PMID: 31063458. ## 14. Cunha PM, Nunes JP, Tomeleri CM, Nascimento MA, Schoenfeld BJ, Antunes M, et al. Resistance Training performed with single and multiple sets induces similar improvement in muscular strength, muscle mass, muscle quality, and IGF-1 in older women: a randomised controlled trail. J Strength Cond Res. 2020;34(4):1008-1016. doi: 10.1519/JSC.0000000000002847. PubMed PMID: 30272625. ## 15. Willoughby DS. Effects of heavy resistance training on myostatin mRNA and protein expression. Med Sci Sports Exerc. 2004;36(4):574‑82. doi: 10.1249/01.mss.0000121952.71533.ea. PubMed PMID: 15064583. ## 16. Viana JU, Dias JMD, Batista PP, Silva SLA, Dias RC, Lustosa LP. Effect of a resistance exercise program for sarcopenic elderly women: quasi-experimental study. Fisioter Mov. 2018. doi: 10.1590/1980-5918.031.AO11. ## 17. Tsekoura M, Billis E, Tsepis E, Dimitriadis Z, Matzaroglou C, Tyllianakis M, et al. The Effects of Group and Home-Based Exercise Programs in Elderly with Sarcopenia: A Randomized Controlled Trial. J Clin Med. 2018;7(12):480. doi: 10.3390/jcm7120480. PubMed PMID: 30486262; PubMed Central PMCID: PMC6306785. ## 18. Lee DC, Shook RP, Drenowatz C, Blair SN. Physical activity and sarcopenic obesity: definition, assessment, prevalence and mechanism. Future Sci OA. 2016;2(3):FSO127. doi: 10.4155/fsoa-2016-0028. PubMed PMID: 28031974; PubMed Central PMCID: PMC5137918. ## 19. Steele J, Raubold K, Kemmler W, Fisher J, Gentil P, Giessing J. The Effects of 6 Months of Progressive High Effort Resistance Training Methods upon Strength, Body Composition, Function, and Wellbeing of Elderly Adults. Biomed Res Int. 2017;2017:2541090. doi: 10.1155/2017/2541090. PubMed PMID: 28676855; PubMed Central PMCID: PMC5476889. ## 20. Shehata A, Mahmoud I. Effect of High Intensity Interval Training (HIIT) on weight, body mass index and body fat oercentage for adults. Science, Movement and Health. 2018;18(2):125-130. ## 21. Moro T, Tinsley G, Bianco A, Gottardi A, Gottardi GB, Faggian D, et al. High intensity interval resistance training (HIIRT) in older adults: Effects on body composition, strength, anabolic hormones and blood lipids. Exp Gerontol. 2017;98:91-98. doi: 10.1016/j.exger.2017.08.015. PubMed PMID: 28821429. ## 22. Makizako H, Nakai Y, Tomioka K, Taniguchi Y, Sato N, Wada A, et al. Effects of a Multicomponent Exercise Program in Physical Function and Muscle Mass in Sarcopenic/Pre-Sarcopenic Adults. J Clin Med. 2020;9(5):1386. doi: 10.3390/jcm9051386. PubMed PMID: 32397192; PubMed Central PMCID: PMC7291119. ## 23. Park SS, Kwon ES, Kwon KS. Molecular mechanisms and therapeutic interventions in sarcopenia. Osteoporos Sarcopenia. 2017;3(3):117-122. doi: 10.1016/j.afos.2017.08.098. PubMed PMID: 30775515; PubMed Central PMCID: PMC6372765. ## 24. Villanueva MG, Lane CJ, Schroeder ET. Short rest interval lengths between sets optimally enhance body composition and performance with 8 weeks of strength resistance training in older men. Eur J Appl Physiol. 2015;115(2):295-308. doi: 10.1007/s00421-014-3014-7. PubMed PMID: 25294666. ## 25. Paoli A, Pacelli QF, Moro T, Marcolin G, Neri M, Battaglia G, et al. Effects of high-intensity circuit training, low-intensity circuit training and endurance training on blood pressure and lipoproteins in middle-aged overweight men. Lipids Health Dis. 2013;12:131. doi: 10.1186/1476-511X-12-131. PubMed PMID: 24004639; PubMed Central PMCID: PMC3846819. ## 26. Marcos-Pardo PJ, Martínez-Rodríguez A, Gil-Arias A. Impact of a motivational resistance training programme on adherence and body composition in the elderly. Sci Rep. 2018;8(1):1370. doi: 10.1038/s41598-018-19764-6. PubMed PMID: 29358716; PubMed Central PMCID: PMC5778069. ## 27. Kanegusuku H, Queiroz AC, Silva VJ, Mello MTD, Ugrinowitsch C, Forjaz CL. High-intensity progressive resistance training increases strength with no change in cardiovascular function and autonomic neural regulation in older adults. J Aging Phys Act. 2015;23(3):339-45. doi: 10.1123/japa.2012-0324. PubMed PMID: 25007720. ## 28. Maillard F, Pereira B, Boiseaue N. Effect of high intensity interval training on total, abdominal and visceral fat: A Meta Analysis. Sports Med. 2018;48(2):269-288. doi: 10.1007/s40279-017-0807-y. PubMed PMID: 29127602. ## 29. Miller MB, Pearcey GEP, Cahill F, McCarthy H, Stratton SBD, Noftall JC, et All. The effect of a short-term high-intensity circuit training program on work capacity, body composition, and blood profiles in sedentary obese men: a pilot study. Biomed Res Int. 2014;2014:191797. doi: 10.1155/2014/191797. PubMed PMID: 24707476; PubMed Central PMCID: PMC3953517. ## 30. Kemmler W, Kohl M, Fröhlich M, Engelke K, von Stengel S, Schoene D. Effects of High-Intensity Resistance Training on Fitness and Fatness in Older Men With Osteosarcopenia. Front Physiol. 2020;11:1014. doi: 10.3389/fphys.2020.01014. PubMed PMID: 32973550; PubMed Central PMCID: PMC7481458. ## 31. de Souza Vale RG, Ferrão MLD, Nunes RAM, Silva JB, Júnior RJN, Dantas EHM. Muscle Strength, GH and IGF-1 in older women submitted to land and aquatic resistance training. Rev Bras Med Esporte.2017;23(4). doi: 10.1590/1517-869220172304163788. ## 32. Hofmann M, Schober-Halper B, Oesen S, Franzke B, Tschan H, Bachl N, et al. Effects of elastic band resistance training and nutri-tional supplementation on muscle quality and circulating muscle growth and degradation factors of institutionalized elderly women: The Vienna Active Ageing Study (VAAS). Eur J Appl Physiol. 2016;116(5):885-97. doi: 10.1007/s00421-016-3344-8. PubMed PMID: 26931422; PubMed Central PMCID: PMC4834098. ## 33. Negaresh R, Ranjbar R, Gharibvand MM, Habibi A, Moktarzade M. Effect of 8-Week Resistance Training on Hypertrophy, Strength, and Myostatin Concentration in Old and Young Men. Salmand: Iranian Journal of Ageing. 2017;12(1):56-67. doi: 10.21859/sija-120154. Persian. ## 34. Kim JS, Petrella JK, Cross JM, Bamman MM. Load-mediated downregulation of myostatin mRNA is not sufficient to promote myofiber hypertrophy in humans: a cluster analysis. J Appl Physiol. 2007;103(5):1488-95. doi: 10.1152/japplphysiol.01194.2006. PubMed PMID: 17673556. ## 35. Kalinkovich A, Livshits G. Sarcopenia –The search for emerging biomarkers. Ageing Res Rev. 2015;22:58–71. doi: 10.1016/j.arr.2015.05.001. PubMed PMID: 25962896. ##
آمار تعداد مشاهده مقاله: 555 تعداد دریافت فایل اصل مقاله: 513

سامانه مدیریت نشریات علمی. قدرت گرفته از سیناوب

پیوندهای مفید

پیوندهای مفید

آمار

Effect of High-Intensity Interval Resistance Training on Appendicular Skeletal Muscle Mass Index Measured by Bioelectric Impedance Analysis in Sarcopenic Elderly Women